| Full name: solute carrier family 4 member 7 | Alias Symbol: NBC3|SBC2 | ||
| Type: protein-coding gene | Cytoband: 3p24.1 | ||
| Entrez ID: 9497 | HGNC ID: HGNC:11033 | Ensembl Gene: ENSG00000033867 | OMIM ID: 603353 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC4A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC4A7 | 9497 | 209884_s_at | -0.1917 | 0.5948 | |
| GSE20347 | SLC4A7 | 9497 | 207604_s_at | 0.3053 | 0.0116 | |
| GSE23400 | SLC4A7 | 9497 | 207604_s_at | 0.0272 | 0.7192 | |
| GSE26886 | SLC4A7 | 9497 | 207604_s_at | -0.5938 | 0.0297 | |
| GSE29001 | SLC4A7 | 9497 | 209884_s_at | -0.0948 | 0.5718 | |
| GSE38129 | SLC4A7 | 9497 | 207604_s_at | 0.1063 | 0.5562 | |
| GSE45670 | SLC4A7 | 9497 | 209884_s_at | -0.5830 | 0.0016 | |
| GSE53622 | SLC4A7 | 9497 | 41470 | 0.0706 | 0.5180 | |
| GSE53624 | SLC4A7 | 9497 | 41470 | -0.0966 | 0.2570 | |
| GSE63941 | SLC4A7 | 9497 | 209884_s_at | -2.5418 | 0.0015 | |
| GSE77861 | SLC4A7 | 9497 | 209884_s_at | 0.0085 | 0.9601 | |
| GSE97050 | SLC4A7 | 9497 | A_24_P368575 | -0.1404 | 0.4497 | |
| SRP007169 | SLC4A7 | 9497 | RNAseq | 0.5051 | 0.3244 | |
| SRP008496 | SLC4A7 | 9497 | RNAseq | 0.7748 | 0.0054 | |
| SRP064894 | SLC4A7 | 9497 | RNAseq | -0.2778 | 0.4571 | |
| SRP133303 | SLC4A7 | 9497 | RNAseq | 0.1687 | 0.5225 | |
| SRP159526 | SLC4A7 | 9497 | RNAseq | -0.3610 | 0.3639 | |
| SRP193095 | SLC4A7 | 9497 | RNAseq | -0.2814 | 0.2340 | |
| SRP219564 | SLC4A7 | 9497 | RNAseq | -0.6805 | 0.1877 | |
| TCGA | SLC4A7 | 9497 | RNAseq | -0.0348 | 0.6651 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC4A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC4A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC4A7 | 9497 | 0 | 18 | 12 | |
| GSE20123 | SLC4A7 | 9497 | 0 | 18 | 12 | |
| GSE43470 | SLC4A7 | 9497 | 0 | 20 | 23 | |
| GSE46452 | SLC4A7 | 9497 | 2 | 17 | 40 | |
| GSE47630 | SLC4A7 | 9497 | 1 | 24 | 15 | |
| GSE54993 | SLC4A7 | 9497 | 6 | 2 | 62 | |
| GSE54994 | SLC4A7 | 9497 | 1 | 32 | 20 | |
| GSE60625 | SLC4A7 | 9497 | 5 | 0 | 6 | |
| GSE74703 | SLC4A7 | 9497 | 0 | 17 | 19 | |
| GSE74704 | SLC4A7 | 9497 | 0 | 12 | 8 | |
| TCGA | SLC4A7 | 9497 | 2 | 68 | 26 |
Total number of gains: 17; Total number of losses: 228; Total Number of normals: 243.
Somatic mutations of SLC4A7:
Generating mutation plots.
Highly correlated genes for SLC4A7:
Showing top 20/49 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC4A7 | WNT2B | 0.715943 | 3 | 0 | 3 |
| SLC4A7 | CEP85L | 0.67392 | 3 | 0 | 3 |
| SLC4A7 | GSTM5 | 0.666032 | 4 | 0 | 4 |
| SLC4A7 | RBM24 | 0.659636 | 3 | 0 | 3 |
| SLC4A7 | MOB1B | 0.65863 | 3 | 0 | 3 |
| SLC4A7 | FBXL7 | 0.653387 | 3 | 0 | 3 |
| SLC4A7 | TCEAL7 | 0.652714 | 5 | 0 | 5 |
| SLC4A7 | ZNF781 | 0.647802 | 3 | 0 | 3 |
| SLC4A7 | RASGRF2 | 0.629344 | 4 | 0 | 4 |
| SLC4A7 | NDNF | 0.627748 | 4 | 0 | 3 |
| SLC4A7 | DNM3OS | 0.622498 | 3 | 0 | 3 |
| SLC4A7 | GALNT15 | 0.618668 | 3 | 0 | 3 |
| SLC4A7 | PTGDS | 0.613999 | 4 | 0 | 4 |
| SLC4A7 | DENND6A | 0.612966 | 4 | 0 | 3 |
| SLC4A7 | RNF150 | 0.612144 | 3 | 0 | 3 |
| SLC4A7 | IL17D | 0.610579 | 3 | 0 | 3 |
| SLC4A7 | SMARCA1 | 0.603081 | 4 | 0 | 3 |
| SLC4A7 | SMIM10 | 0.601544 | 3 | 0 | 3 |
| SLC4A7 | ECM2 | 0.600022 | 5 | 0 | 3 |
| SLC4A7 | LINC01082 | 0.599866 | 3 | 0 | 3 |
For details and further investigation, click here
