| Full name: DENN domain containing 6A | Alias Symbol: FLJ34969|AFI1A | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 201627 | HGNC ID: HGNC:26635 | Ensembl Gene: ENSG00000174839 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DENND6A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DENND6A | 201627 | 226965_at | -0.1772 | 0.5401 | |
| GSE26886 | DENND6A | 201627 | 226965_at | -0.6158 | 0.0001 | |
| GSE45670 | DENND6A | 201627 | 226965_at | -0.2058 | 0.0654 | |
| GSE53622 | DENND6A | 201627 | 67422 | -0.3827 | 0.0000 | |
| GSE53624 | DENND6A | 201627 | 67422 | -0.1723 | 0.0014 | |
| GSE63941 | DENND6A | 201627 | 226965_at | 0.2429 | 0.5057 | |
| GSE77861 | DENND6A | 201627 | 226965_at | 0.0145 | 0.9521 | |
| SRP007169 | DENND6A | 201627 | RNAseq | 0.2753 | 0.4406 | |
| SRP008496 | DENND6A | 201627 | RNAseq | 0.4412 | 0.0383 | |
| SRP064894 | DENND6A | 201627 | RNAseq | -0.1604 | 0.3568 | |
| SRP133303 | DENND6A | 201627 | RNAseq | -0.1428 | 0.3707 | |
| SRP159526 | DENND6A | 201627 | RNAseq | -0.2489 | 0.0962 | |
| SRP193095 | DENND6A | 201627 | RNAseq | -0.1658 | 0.0146 | |
| SRP219564 | DENND6A | 201627 | RNAseq | -0.4313 | 0.1434 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DENND6A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of DENND6A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DENND6A | 201627 | 0 | 17 | 13 | |
| GSE20123 | DENND6A | 201627 | 0 | 18 | 12 | |
| GSE43470 | DENND6A | 201627 | 0 | 17 | 26 | |
| GSE46452 | DENND6A | 201627 | 2 | 17 | 40 | |
| GSE47630 | DENND6A | 201627 | 1 | 24 | 15 | |
| GSE54993 | DENND6A | 201627 | 6 | 2 | 62 | |
| GSE54994 | DENND6A | 201627 | 0 | 32 | 21 | |
| GSE60625 | DENND6A | 201627 | 5 | 0 | 6 | |
| GSE74703 | DENND6A | 201627 | 0 | 14 | 22 | |
| GSE74704 | DENND6A | 201627 | 0 | 11 | 9 | |
| TCGA | DENND6A | 201627 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of DENND6A:
Generating mutation plots.
Highly correlated genes for DENND6A:
Showing top 20/41 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DENND6A | MBNL2 | 0.66651 | 3 | 0 | 3 |
| DENND6A | FGD5-AS1 | 0.647504 | 5 | 0 | 5 |
| DENND6A | ISOC1 | 0.635381 | 4 | 0 | 3 |
| DENND6A | CSDE1 | 0.619649 | 3 | 0 | 3 |
| DENND6A | SLC4A7 | 0.612966 | 4 | 0 | 3 |
| DENND6A | GID4 | 0.607804 | 3 | 0 | 3 |
| DENND6A | BDP1 | 0.60612 | 4 | 0 | 3 |
| DENND6A | PJA2 | 0.595635 | 5 | 0 | 3 |
| DENND6A | AKAP11 | 0.595252 | 3 | 0 | 3 |
| DENND6A | SLMAP | 0.590968 | 6 | 0 | 4 |
| DENND6A | EAF1 | 0.583006 | 3 | 0 | 3 |
| DENND6A | ANKRD28 | 0.576443 | 3 | 0 | 3 |
| DENND6A | MMP28 | 0.571097 | 3 | 0 | 3 |
| DENND6A | ROCK2 | 0.565067 | 4 | 0 | 3 |
| DENND6A | SP1 | 0.563523 | 3 | 0 | 3 |
| DENND6A | CTDSPL | 0.562413 | 4 | 0 | 3 |
| DENND6A | MLH1 | 0.559778 | 6 | 0 | 4 |
| DENND6A | PCGF5 | 0.557303 | 3 | 0 | 3 |
| DENND6A | IBTK | 0.552898 | 4 | 0 | 3 |
| DENND6A | PDE12 | 0.551459 | 3 | 0 | 3 |
For details and further investigation, click here
