| Full name: Wnt family member 2B | Alias Symbol: XWNT2 | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 7482 | HGNC ID: HGNC:12781 | Ensembl Gene: ENSG00000134245 | OMIM ID: 601968 |
| Drug and gene relationship at DGIdb | |||
WNT2B involved pathways:
Expression of WNT2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WNT2B | 7482 | 238512_at | -0.7065 | 0.6375 | |
| GSE20347 | WNT2B | 7482 | 206459_s_at | 0.0291 | 0.7628 | |
| GSE23400 | WNT2B | 7482 | 206459_s_at | 0.0119 | 0.8039 | |
| GSE26886 | WNT2B | 7482 | 238512_at | -0.5709 | 0.4030 | |
| GSE29001 | WNT2B | 7482 | 206458_s_at | 0.2972 | 0.3472 | |
| GSE38129 | WNT2B | 7482 | 206458_s_at | 0.0653 | 0.8123 | |
| GSE45670 | WNT2B | 7482 | 238512_at | -0.9534 | 0.0756 | |
| GSE53622 | WNT2B | 7482 | 28078 | -0.6953 | 0.0002 | |
| GSE53624 | WNT2B | 7482 | 28078 | -0.2298 | 0.0392 | |
| GSE63941 | WNT2B | 7482 | 238512_at | -3.4712 | 0.0008 | |
| GSE77861 | WNT2B | 7482 | 238512_at | 0.1806 | 0.6837 | |
| GSE97050 | WNT2B | 7482 | A_23_P138352 | -0.4287 | 0.3462 | |
| SRP007169 | WNT2B | 7482 | RNAseq | 0.7188 | 0.1446 | |
| SRP008496 | WNT2B | 7482 | RNAseq | 0.7684 | 0.1198 | |
| SRP064894 | WNT2B | 7482 | RNAseq | -0.4099 | 0.1455 | |
| SRP133303 | WNT2B | 7482 | RNAseq | -0.2562 | 0.2547 | |
| SRP159526 | WNT2B | 7482 | RNAseq | 0.2153 | 0.7047 | |
| SRP193095 | WNT2B | 7482 | RNAseq | -0.2232 | 0.3044 | |
| SRP219564 | WNT2B | 7482 | RNAseq | -0.8975 | 0.0171 | |
| TCGA | WNT2B | 7482 | RNAseq | 0.0787 | 0.7015 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by WNT2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WNT2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WNT2B | 7482 | 0 | 10 | 20 | |
| GSE20123 | WNT2B | 7482 | 0 | 10 | 20 | |
| GSE43470 | WNT2B | 7482 | 0 | 8 | 35 | |
| GSE46452 | WNT2B | 7482 | 2 | 1 | 56 | |
| GSE47630 | WNT2B | 7482 | 9 | 5 | 26 | |
| GSE54993 | WNT2B | 7482 | 0 | 1 | 69 | |
| GSE54994 | WNT2B | 7482 | 7 | 4 | 42 | |
| GSE60625 | WNT2B | 7482 | 0 | 0 | 11 | |
| GSE74703 | WNT2B | 7482 | 0 | 7 | 29 | |
| GSE74704 | WNT2B | 7482 | 0 | 6 | 14 | |
| TCGA | WNT2B | 7482 | 7 | 28 | 61 |
Total number of gains: 25; Total number of losses: 80; Total Number of normals: 383.
Somatic mutations of WNT2B:
Generating mutation plots.
Highly correlated genes for WNT2B:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WNT2B | SLC4A7 | 0.715943 | 3 | 0 | 3 |
| WNT2B | MID1 | 0.704495 | 3 | 0 | 3 |
| WNT2B | ZC3H6 | 0.689721 | 3 | 0 | 3 |
| WNT2B | BRAF | 0.679244 | 4 | 0 | 3 |
| WNT2B | ZNF630 | 0.668637 | 3 | 0 | 3 |
| WNT2B | FASTK | 0.665515 | 3 | 0 | 3 |
| WNT2B | TNNI3K | 0.647987 | 3 | 0 | 3 |
| WNT2B | SMR3A | 0.637038 | 3 | 0 | 3 |
| WNT2B | CUTC | 0.619105 | 3 | 0 | 3 |
| WNT2B | HEBP1 | 0.612256 | 5 | 0 | 3 |
| WNT2B | ZNF763 | 0.609196 | 4 | 0 | 4 |
| WNT2B | CYB561D1 | 0.605773 | 4 | 0 | 3 |
| WNT2B | ZNF682 | 0.599916 | 4 | 0 | 3 |
| WNT2B | CD9 | 0.597048 | 5 | 0 | 3 |
| WNT2B | TRAPPC6A | 0.586028 | 4 | 0 | 4 |
| WNT2B | CACNB3 | 0.579833 | 3 | 0 | 3 |
| WNT2B | KDM7A | 0.567256 | 3 | 0 | 3 |
| WNT2B | CLDN23 | 0.562718 | 3 | 0 | 3 |
| WNT2B | PTCH1 | 0.545534 | 6 | 0 | 3 |
| WNT2B | VAMP4 | 0.528878 | 6 | 0 | 3 |
For details and further investigation, click here
