| Full name: extracellular matrix protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q22.31 | ||
| Entrez ID: 1842 | HGNC ID: HGNC:3154 | Ensembl Gene: ENSG00000106823 | OMIM ID: 603479 |
| Drug and gene relationship at DGIdb | |||
Expression of ECM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECM2 | 1842 | 206101_at | -0.5387 | 0.5849 | |
| GSE20347 | ECM2 | 1842 | 206101_at | 0.2868 | 0.3750 | |
| GSE23400 | ECM2 | 1842 | 206101_at | -0.0261 | 0.8468 | |
| GSE26886 | ECM2 | 1842 | 206101_at | 0.3236 | 0.4276 | |
| GSE29001 | ECM2 | 1842 | 206101_at | 0.3618 | 0.4152 | |
| GSE38129 | ECM2 | 1842 | 206101_at | -0.2245 | 0.6497 | |
| GSE45670 | ECM2 | 1842 | 206101_at | -1.7724 | 0.0002 | |
| GSE53622 | ECM2 | 1842 | 52009 | 0.1046 | 0.5282 | |
| GSE53624 | ECM2 | 1842 | 52009 | 0.3792 | 0.0219 | |
| GSE63941 | ECM2 | 1842 | 206101_at | -2.1380 | 0.0736 | |
| GSE77861 | ECM2 | 1842 | 1568779_a_at | -0.1644 | 0.1567 | |
| GSE97050 | ECM2 | 1842 | A_23_P216434 | -0.0476 | 0.8414 | |
| SRP007169 | ECM2 | 1842 | RNAseq | 2.3889 | 0.0000 | |
| SRP008496 | ECM2 | 1842 | RNAseq | 2.9767 | 0.0000 | |
| SRP064894 | ECM2 | 1842 | RNAseq | 0.5540 | 0.1724 | |
| SRP133303 | ECM2 | 1842 | RNAseq | 0.4980 | 0.0145 | |
| SRP159526 | ECM2 | 1842 | RNAseq | -0.2743 | 0.5934 | |
| SRP193095 | ECM2 | 1842 | RNAseq | 1.0000 | 0.0000 | |
| SRP219564 | ECM2 | 1842 | RNAseq | 0.3480 | 0.5943 | |
| TCGA | ECM2 | 1842 | RNAseq | -0.1231 | 0.3862 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by ECM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ECM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECM2 | 1842 | 6 | 9 | 15 | |
| GSE20123 | ECM2 | 1842 | 6 | 9 | 15 | |
| GSE43470 | ECM2 | 1842 | 6 | 3 | 34 | |
| GSE46452 | ECM2 | 1842 | 6 | 14 | 39 | |
| GSE47630 | ECM2 | 1842 | 1 | 17 | 22 | |
| GSE54993 | ECM2 | 1842 | 4 | 2 | 64 | |
| GSE54994 | ECM2 | 1842 | 8 | 11 | 34 | |
| GSE60625 | ECM2 | 1842 | 0 | 0 | 11 | |
| GSE74703 | ECM2 | 1842 | 5 | 3 | 28 | |
| GSE74704 | ECM2 | 1842 | 3 | 7 | 10 | |
| TCGA | ECM2 | 1842 | 24 | 24 | 48 |
Total number of gains: 69; Total number of losses: 99; Total Number of normals: 320.
Somatic mutations of ECM2:
Generating mutation plots.
Highly correlated genes for ECM2:
Showing top 20/238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECM2 | NAP1L3 | 0.756337 | 8 | 0 | 7 |
| ECM2 | MFAP5 | 0.733206 | 9 | 0 | 9 |
| ECM2 | ZFPM2 | 0.723109 | 8 | 0 | 7 |
| ECM2 | CDC42EP2 | 0.71838 | 3 | 0 | 3 |
| ECM2 | TIMP3 | 0.718248 | 7 | 0 | 7 |
| ECM2 | RASGRF2 | 0.718119 | 3 | 0 | 3 |
| ECM2 | ABCA9 | 0.710208 | 3 | 0 | 3 |
| ECM2 | MMP23B | 0.708282 | 3 | 0 | 3 |
| ECM2 | OMD | 0.69744 | 10 | 0 | 8 |
| ECM2 | LINC01279 | 0.688131 | 3 | 0 | 3 |
| ECM2 | HEPH | 0.685306 | 10 | 0 | 9 |
| ECM2 | TRIM52 | 0.681686 | 3 | 0 | 3 |
| ECM2 | MPZ | 0.679139 | 3 | 0 | 3 |
| ECM2 | NDNF | 0.6781 | 6 | 0 | 5 |
| ECM2 | GNAZ | 0.677565 | 4 | 0 | 3 |
| ECM2 | TCEAL7 | 0.672385 | 7 | 0 | 5 |
| ECM2 | MPDZ | 0.66861 | 7 | 0 | 6 |
| ECM2 | CPQ | 0.666135 | 8 | 0 | 6 |
| ECM2 | LAMB2 | 0.665451 | 6 | 0 | 5 |
| ECM2 | FAT4 | 0.660436 | 8 | 0 | 6 |
For details and further investigation, click here
