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Severity: Warning

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Line Number: 123

Backtrace:

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 123
Function: exec

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
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Function: drawSurvPlot

File: /data/webapp/var/www/html/ESCCdb/index.php
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Function: require_once

Multi-Omics Database of ESCC

 

CEP85L

 

Full name: centrosomal protein 85 like Alias Symbol: NY-BR-15|bA57K17.2
Type: protein-coding gene Cytoband: 6q22.31
Entrez ID: 387119 HGNC ID: HGNC:21638 Ensembl Gene: ENSG00000111860 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of CEP85L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CEP85L 387119 228007_at -0.2617 0.6175
GSE26886 CEP85L 387119 228007_at 0.8984 0.0376
GSE45670 CEP85L 387119 228007_at -0.9499 0.0003
GSE53622 CEP85L 387119 21059 -0.5509 0.0000
GSE53624 CEP85L 387119 21059 -0.4690 0.0000
GSE63941 CEP85L 387119 228007_at -2.5418 0.0004
GSE77861 CEP85L 387119 228007_at 0.2774 0.1956
SRP007169 CEP85L 387119 RNAseq 0.4138 0.4800
SRP008496 CEP85L 387119 RNAseq 1.1483 0.0058
SRP064894 CEP85L 387119 RNAseq -0.1726 0.6041
SRP133303 CEP85L 387119 RNAseq -0.6195 0.0008
SRP159526 CEP85L 387119 RNAseq -0.3789 0.3405
SRP193095 CEP85L 387119 RNAseq -0.1643 0.6248
SRP219564 CEP85L 387119 RNAseq -0.0201 0.9611

Upregulated datasets: 1; Downregulated datasets: 1.  

 

Survival by CEP85L expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of CEP85L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CEP85L 387119 1 4 25
GSE20123 CEP85L 387119 1 3 26
GSE43470 CEP85L 387119 4 1 38
GSE46452 CEP85L 387119 2 11 46
GSE47630 CEP85L 387119 9 4 27
GSE54993 CEP85L 387119 3 2 65
GSE54994 CEP85L 387119 8 8 37
GSE60625 CEP85L 387119 0 1 10
GSE74703 CEP85L 387119 3 1 32
GSE74704 CEP85L 387119 0 1 19
TCGA CEP85L 387119 10 20 66

Total number of gains: 41; Total number of losses: 56; Total Number of normals: 391.  

 

Somatic mutations of CEP85L:

 

Generating mutation plots.

 

Highly correlated genes for CEP85L:

 

Showing top 20/522 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CEP85LARHGAP60.745519404
CEP85LEDNRB0.73059404
CEP85LGNG20.711255404
CEP85LENTPD40.702745303
CEP85LCDH110.68726303
CEP85LFZD40.687021404
CEP85LTRPC60.68511303
CEP85LFBLN50.683282707
CEP85LSLC4A70.67392303
CEP85LSYNE10.672174605
CEP85LSMAD90.671141505
CEP85LCPED10.670368404
CEP85LNEGR10.670062404
CEP85LARNT20.669656303
CEP85LMCAM0.668785505
CEP85LSTARD130.667883605
CEP85LKCTD120.665785707
CEP85LDCHS10.663998404
CEP85LRAI140.663588303
CEP85LENPP40.661383303

For details and further investigation, click here