| Full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | Alias Symbol: SNF2LB|NURF140|ISWI|SWI|hSNF2L | ||
| Type: protein-coding gene | Cytoband: Xq25-q26.1 | ||
| Entrez ID: 6594 | HGNC ID: HGNC:11097 | Ensembl Gene: ENSG00000102038 | OMIM ID: 300012 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SMARCA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMARCA1 | 6594 | 203875_at | -0.4028 | 0.6639 | |
| GSE20347 | SMARCA1 | 6594 | 203875_at | 0.1655 | 0.5921 | |
| GSE23400 | SMARCA1 | 6594 | 203875_at | 0.0687 | 0.4422 | |
| GSE26886 | SMARCA1 | 6594 | 203875_at | 0.9643 | 0.0245 | |
| GSE29001 | SMARCA1 | 6594 | 203875_at | 0.1500 | 0.7301 | |
| GSE38129 | SMARCA1 | 6594 | 203875_at | -0.0208 | 0.9516 | |
| GSE45670 | SMARCA1 | 6594 | 203875_at | -0.4629 | 0.1998 | |
| GSE53622 | SMARCA1 | 6594 | 111500 | -0.1423 | 0.2647 | |
| GSE53624 | SMARCA1 | 6594 | 111500 | 0.0077 | 0.9481 | |
| GSE63941 | SMARCA1 | 6594 | 203875_at | -2.4480 | 0.0130 | |
| GSE77861 | SMARCA1 | 6594 | 203875_at | 0.1775 | 0.4567 | |
| GSE97050 | SMARCA1 | 6594 | A_23_P44244 | -0.5318 | 0.2526 | |
| SRP007169 | SMARCA1 | 6594 | RNAseq | 1.1804 | 0.0307 | |
| SRP008496 | SMARCA1 | 6594 | RNAseq | 1.4271 | 0.0000 | |
| SRP064894 | SMARCA1 | 6594 | RNAseq | 0.4557 | 0.0348 | |
| SRP133303 | SMARCA1 | 6594 | RNAseq | 0.5357 | 0.0464 | |
| SRP159526 | SMARCA1 | 6594 | RNAseq | 0.3909 | 0.3900 | |
| SRP193095 | SMARCA1 | 6594 | RNAseq | 0.5016 | 0.0052 | |
| SRP219564 | SMARCA1 | 6594 | RNAseq | -0.0978 | 0.8851 | |
| TCGA | SMARCA1 | 6594 | RNAseq | -0.2689 | 0.0226 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by SMARCA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMARCA1:
No record found for this gene.
Somatic mutations of SMARCA1:
Generating mutation plots.
Highly correlated genes for SMARCA1:
Showing top 20/421 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMARCA1 | GABRA5 | 0.678596 | 4 | 0 | 4 |
| SMARCA1 | APBB1 | 0.648846 | 6 | 0 | 6 |
| SMARCA1 | CDC42EP3 | 0.64599 | 6 | 0 | 5 |
| SMARCA1 | FOXL2 | 0.644011 | 3 | 0 | 3 |
| SMARCA1 | VIP | 0.642187 | 5 | 0 | 5 |
| SMARCA1 | UBE2Q2 | 0.641104 | 3 | 0 | 3 |
| SMARCA1 | ARHGEF17 | 0.638228 | 5 | 0 | 5 |
| SMARCA1 | SMAD9 | 0.63729 | 7 | 0 | 5 |
| SMARCA1 | SLC4A3 | 0.633599 | 4 | 0 | 3 |
| SMARCA1 | ITGB1BP2 | 0.633145 | 4 | 0 | 4 |
| SMARCA1 | GSTM1 | 0.630707 | 3 | 0 | 3 |
| SMARCA1 | CCDC136 | 0.629419 | 5 | 0 | 4 |
| SMARCA1 | COL21A1 | 0.62686 | 8 | 0 | 8 |
| SMARCA1 | RNF150 | 0.625293 | 5 | 0 | 5 |
| SMARCA1 | MYOM1 | 0.624383 | 5 | 0 | 4 |
| SMARCA1 | SAMD4A | 0.62382 | 4 | 0 | 3 |
| SMARCA1 | NUDT11 | 0.622891 | 3 | 0 | 3 |
| SMARCA1 | MPDZ | 0.622216 | 12 | 0 | 9 |
| SMARCA1 | TMEM106B | 0.621167 | 3 | 0 | 3 |
| SMARCA1 | PRKG2 | 0.618113 | 3 | 0 | 3 |
For details and further investigation, click here
