| Full name: growth hormone releasing hormone receptor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p14.3 | ||
| Entrez ID: 2692 | HGNC ID: HGNC:4266 | Ensembl Gene: ENSG00000106128 | OMIM ID: 139191 |
| Drug and gene relationship at DGIdb | |||
Expression of GHRHR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GHRHR | 2692 | 207825_s_at | 0.0709 | 0.7041 | |
| GSE20347 | GHRHR | 2692 | 207825_s_at | -0.0168 | 0.8819 | |
| GSE23400 | GHRHR | 2692 | 207825_s_at | -0.1072 | 0.0018 | |
| GSE26886 | GHRHR | 2692 | 207825_s_at | -0.1329 | 0.3170 | |
| GSE29001 | GHRHR | 2692 | 211544_s_at | 0.0124 | 0.9207 | |
| GSE38129 | GHRHR | 2692 | 211544_s_at | 0.0106 | 0.9251 | |
| GSE45670 | GHRHR | 2692 | 211545_at | -0.0398 | 0.6859 | |
| GSE53622 | GHRHR | 2692 | 9926 | -1.0508 | 0.0000 | |
| GSE53624 | GHRHR | 2692 | 9926 | -1.2152 | 0.0000 | |
| GSE63941 | GHRHR | 2692 | 207825_s_at | 0.2092 | 0.2164 | |
| GSE77861 | GHRHR | 2692 | 211544_s_at | 0.0406 | 0.8304 | |
| GSE97050 | GHRHR | A_21_P0005370 | 0.0592 | 0.8414 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GHRHR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GHRHR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GHRHR | 2692 | 15 | 0 | 15 | |
| GSE20123 | GHRHR | 2692 | 15 | 0 | 15 | |
| GSE43470 | GHRHR | 2692 | 4 | 0 | 39 | |
| GSE46452 | GHRHR | 2692 | 11 | 1 | 47 | |
| GSE47630 | GHRHR | 2692 | 8 | 1 | 31 | |
| GSE54993 | GHRHR | 2692 | 0 | 6 | 64 | |
| GSE54994 | GHRHR | 2692 | 19 | 3 | 31 | |
| GSE60625 | GHRHR | 2692 | 0 | 0 | 11 | |
| GSE74703 | GHRHR | 2692 | 4 | 0 | 32 | |
| GSE74704 | GHRHR | 2692 | 9 | 0 | 11 | |
| TCGA | GHRHR | 2692 | 55 | 6 | 35 |
Total number of gains: 140; Total number of losses: 17; Total Number of normals: 331.
Somatic mutations of GHRHR:
Generating mutation plots.
Highly correlated genes for GHRHR:
Showing top 20/620 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GHRHR | HMGB4 | 0.81388 | 3 | 0 | 3 |
| GHRHR | BARHL2 | 0.786621 | 3 | 0 | 3 |
| GHRHR | FAM163B | 0.784036 | 3 | 0 | 3 |
| GHRHR | OR10G3 | 0.78403 | 3 | 0 | 3 |
| GHRHR | SNED1 | 0.779884 | 3 | 0 | 3 |
| GHRHR | NLRP5 | 0.761754 | 3 | 0 | 3 |
| GHRHR | SLC5A11 | 0.760481 | 3 | 0 | 3 |
| GHRHR | CLEC18C | 0.75989 | 3 | 0 | 3 |
| GHRHR | C14orf180 | 0.744272 | 4 | 0 | 4 |
| GHRHR | CD164L2 | 0.734437 | 3 | 0 | 3 |
| GHRHR | KBTBD13 | 0.730099 | 3 | 0 | 3 |
| GHRHR | CALML6 | 0.729688 | 5 | 0 | 5 |
| GHRHR | KRTAP20-1 | 0.727413 | 3 | 0 | 3 |
| GHRHR | KCNA7 | 0.722813 | 4 | 0 | 4 |
| GHRHR | OR2Z1 | 0.721222 | 3 | 0 | 3 |
| GHRHR | TRAPPC9 | 0.714077 | 3 | 0 | 3 |
| GHRHR | MFSD2B | 0.71344 | 4 | 0 | 4 |
| GHRHR | TEN1 | 0.713065 | 3 | 0 | 3 |
| GHRHR | VWA5B2 | 0.707949 | 4 | 0 | 3 |
| GHRHR | HMGCLL1 | 0.705465 | 3 | 0 | 3 |
For details and further investigation, click here
