| Full name: snail family transcriptional repressor 1 | Alias Symbol: SNA|SLUGH2|SNAH|SNAIL1|SNAIL | ||
| Type: protein-coding gene | Cytoband: 20q13.13 | ||
| Entrez ID: 6615 | HGNC ID: HGNC:11128 | Ensembl Gene: ENSG00000124216 | OMIM ID: 604238 |
| Drug and gene relationship at DGIdb | |||
SNAI1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04520 | Adherens junction |
Expression of SNAI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNAI1 | 6615 | 219480_at | -0.0150 | 0.9826 | |
| GSE20347 | SNAI1 | 6615 | 219480_at | -0.0263 | 0.6968 | |
| GSE23400 | SNAI1 | 6615 | 219480_at | -0.1221 | 0.0008 | |
| GSE26886 | SNAI1 | 6615 | 219480_at | 0.1020 | 0.5204 | |
| GSE29001 | SNAI1 | 6615 | 219480_at | 0.0330 | 0.8658 | |
| GSE38129 | SNAI1 | 6615 | 219480_at | -0.1763 | 0.0498 | |
| GSE45670 | SNAI1 | 6615 | 219480_at | -0.0770 | 0.5479 | |
| GSE53622 | SNAI1 | 6615 | 46536 | 0.8263 | 0.0000 | |
| GSE53624 | SNAI1 | 6615 | 46536 | 1.1845 | 0.0000 | |
| GSE63941 | SNAI1 | 6615 | 219480_at | -0.3801 | 0.2578 | |
| GSE77861 | SNAI1 | 6615 | 219480_at | -0.1833 | 0.1571 | |
| GSE97050 | SNAI1 | 6615 | A_23_P131846 | 0.3907 | 0.2580 | |
| SRP007169 | SNAI1 | 6615 | RNAseq | 1.9189 | 0.0395 | |
| SRP064894 | SNAI1 | 6615 | RNAseq | 1.0545 | 0.0094 | |
| SRP133303 | SNAI1 | 6615 | RNAseq | 1.1914 | 0.0025 | |
| SRP159526 | SNAI1 | 6615 | RNAseq | 1.0155 | 0.0279 | |
| SRP219564 | SNAI1 | 6615 | RNAseq | 0.2871 | 0.7359 | |
| TCGA | SNAI1 | 6615 | RNAseq | 0.3222 | 0.0504 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by SNAI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNAI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNAI1 | 6615 | 17 | 2 | 11 | |
| GSE20123 | SNAI1 | 6615 | 17 | 2 | 11 | |
| GSE43470 | SNAI1 | 6615 | 13 | 0 | 30 | |
| GSE46452 | SNAI1 | 6615 | 29 | 0 | 30 | |
| GSE47630 | SNAI1 | 6615 | 24 | 1 | 15 | |
| GSE54993 | SNAI1 | 6615 | 0 | 17 | 53 | |
| GSE54994 | SNAI1 | 6615 | 27 | 0 | 26 | |
| GSE60625 | SNAI1 | 6615 | 0 | 0 | 11 | |
| GSE74703 | SNAI1 | 6615 | 11 | 0 | 25 | |
| GSE74704 | SNAI1 | 6615 | 13 | 0 | 7 | |
| TCGA | SNAI1 | 6615 | 47 | 3 | 46 |
Total number of gains: 198; Total number of losses: 25; Total Number of normals: 265.
Somatic mutations of SNAI1:
Generating mutation plots.
Highly correlated genes for SNAI1:
Showing top 20/486 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNAI1 | SHISA7 | 0.803194 | 3 | 0 | 3 |
| SNAI1 | SMOC1 | 0.741436 | 3 | 0 | 3 |
| SNAI1 | OR1J4 | 0.737527 | 3 | 0 | 3 |
| SNAI1 | MRAP | 0.72895 | 3 | 0 | 3 |
| SNAI1 | C16orf82 | 0.724709 | 3 | 0 | 3 |
| SNAI1 | BHLHE23 | 0.714833 | 3 | 0 | 3 |
| SNAI1 | TNFRSF14 | 0.711611 | 3 | 0 | 3 |
| SNAI1 | CLEC4G | 0.707101 | 3 | 0 | 3 |
| SNAI1 | TRIM10 | 0.7042 | 5 | 0 | 4 |
| SNAI1 | OR10H1 | 0.697656 | 4 | 0 | 4 |
| SNAI1 | GPBAR1 | 0.697417 | 3 | 0 | 3 |
| SNAI1 | LACRT | 0.697331 | 4 | 0 | 4 |
| SNAI1 | TMEM190 | 0.696008 | 3 | 0 | 3 |
| SNAI1 | PMEPA1 | 0.694042 | 4 | 0 | 4 |
| SNAI1 | C20orf85 | 0.691645 | 3 | 0 | 3 |
| SNAI1 | FERD3L | 0.689545 | 4 | 0 | 3 |
| SNAI1 | KCNT1 | 0.686519 | 3 | 0 | 3 |
| SNAI1 | NKD1 | 0.685894 | 3 | 0 | 3 |
| SNAI1 | ATCAY | 0.684385 | 4 | 0 | 3 |
| SNAI1 | DNMT3B | 0.684104 | 3 | 0 | 3 |
For details and further investigation, click here
