| Full name: SPARC related modular calcium binding 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q24.1 | ||
| Entrez ID: 64093 | HGNC ID: HGNC:20318 | Ensembl Gene: ENSG00000198732 | OMIM ID: 608488 |
| Drug and gene relationship at DGIdb | |||
Expression of SMOC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMOC1 | 64093 | 222784_at | 0.0058 | 0.9885 | |
| GSE26886 | SMOC1 | 64093 | 222784_at | -0.1191 | 0.5377 | |
| GSE45670 | SMOC1 | 64093 | 222784_at | 0.0672 | 0.6433 | |
| GSE53622 | SMOC1 | 64093 | 47796 | 0.1404 | 0.0708 | |
| GSE53624 | SMOC1 | 64093 | 47796 | 0.1855 | 0.0459 | |
| GSE63941 | SMOC1 | 64093 | 222784_at | -0.1384 | 0.8322 | |
| GSE77861 | SMOC1 | 64093 | 222784_at | -0.0104 | 0.9230 | |
| GSE97050 | SMOC1 | 64093 | A_33_P3333603 | -0.1443 | 0.4700 | |
| SRP133303 | SMOC1 | 64093 | RNAseq | -0.3012 | 0.6077 | |
| SRP159526 | SMOC1 | 64093 | RNAseq | 3.5051 | 0.0001 | |
| SRP219564 | SMOC1 | 64093 | RNAseq | 4.0496 | 0.0003 | |
| TCGA | SMOC1 | 64093 | RNAseq | -0.4131 | 0.4272 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SMOC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMOC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMOC1 | 64093 | 8 | 3 | 19 | |
| GSE20123 | SMOC1 | 64093 | 8 | 3 | 19 | |
| GSE43470 | SMOC1 | 64093 | 8 | 3 | 32 | |
| GSE46452 | SMOC1 | 64093 | 16 | 3 | 40 | |
| GSE47630 | SMOC1 | 64093 | 11 | 9 | 20 | |
| GSE54993 | SMOC1 | 64093 | 3 | 9 | 58 | |
| GSE54994 | SMOC1 | 64093 | 18 | 5 | 30 | |
| GSE60625 | SMOC1 | 64093 | 0 | 2 | 9 | |
| GSE74703 | SMOC1 | 64093 | 7 | 3 | 26 | |
| GSE74704 | SMOC1 | 64093 | 3 | 3 | 14 | |
| TCGA | SMOC1 | 64093 | 32 | 16 | 48 |
Total number of gains: 114; Total number of losses: 59; Total Number of normals: 315.
Somatic mutations of SMOC1:
Generating mutation plots.
Highly correlated genes for SMOC1:
Showing top 20/233 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMOC1 | AMHR2 | 0.779177 | 3 | 0 | 3 |
| SMOC1 | TESC | 0.759545 | 3 | 0 | 3 |
| SMOC1 | KAZALD1 | 0.759082 | 3 | 0 | 3 |
| SMOC1 | ZKSCAN2 | 0.752762 | 3 | 0 | 3 |
| SMOC1 | SPEF1 | 0.752266 | 3 | 0 | 3 |
| SMOC1 | NXNL1 | 0.747449 | 3 | 0 | 3 |
| SMOC1 | SNAI1 | 0.741436 | 3 | 0 | 3 |
| SMOC1 | ALKBH5 | 0.734857 | 3 | 0 | 3 |
| SMOC1 | C10orf91 | 0.734548 | 4 | 0 | 4 |
| SMOC1 | OR4D2 | 0.728507 | 3 | 0 | 3 |
| SMOC1 | CALCA | 0.726485 | 3 | 0 | 3 |
| SMOC1 | CCL26 | 0.722814 | 3 | 0 | 3 |
| SMOC1 | CES3 | 0.718674 | 3 | 0 | 3 |
| SMOC1 | ASRGL1 | 0.708229 | 3 | 0 | 3 |
| SMOC1 | GUCY2C | 0.702656 | 3 | 0 | 3 |
| SMOC1 | MAPK8IP2 | 0.699588 | 3 | 0 | 3 |
| SMOC1 | PRAMEF12 | 0.698907 | 3 | 0 | 3 |
| SMOC1 | PPEF1 | 0.697943 | 3 | 0 | 3 |
| SMOC1 | AQP6 | 0.695473 | 3 | 0 | 3 |
| SMOC1 | TMEM229A | 0.693411 | 3 | 0 | 3 |
For details and further investigation, click here
