PMEPA1

 

Full name: prostate transmembrane protein, androgen induced 1 Alias Symbol: STAG1
Type: protein-coding gene Cytoband: 20q13.31
Entrez ID: 56937 HGNC ID: HGNC:14107 Ensembl Gene: ENSG00000124225 OMIM ID: 606564
Drug and gene relationship at DGIdb

 

Expression of PMEPA1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PMEPA1 56937 222450_at 1.1304 0.2327
GSE20347 PMEPA1 56937 217875_s_at 1.4958 0.0000
GSE23400 PMEPA1 56937 217875_s_at 1.2123 0.0000
GSE26886 PMEPA1 56937 222450_at 3.4737 0.0000
GSE29001 PMEPA1 56937 217875_s_at 1.5164 0.0032
GSE38129 PMEPA1 56937 217875_s_at 1.5828 0.0001
GSE45670 PMEPA1 56937 222449_at 1.3639 0.0143
GSE53622 PMEPA1 56937 33598 1.7485 0.0000
GSE53624 PMEPA1 56937 33598 1.9483 0.0000
GSE63941 PMEPA1 56937 222450_at -0.2379 0.9036
GSE77861 PMEPA1 56937 217875_s_at 0.7922 0.1447
GSE97050 PMEPA1 56937 A_33_P3403867 0.9493 0.1998
SRP007169 PMEPA1 56937 RNAseq 3.3355 0.0000
SRP008496 PMEPA1 56937 RNAseq 3.6396 0.0000
SRP064894 PMEPA1 56937 RNAseq 2.2624 0.0000
SRP133303 PMEPA1 56937 RNAseq 2.5141 0.0000
SRP159526 PMEPA1 56937 RNAseq 2.5720 0.0002
SRP193095 PMEPA1 56937 RNAseq 3.3646 0.0000
SRP219564 PMEPA1 56937 RNAseq 1.6009 0.0251
TCGA PMEPA1 56937 RNAseq 0.4062 0.0002

Upregulated datasets: 15; Downregulated datasets: 0.  


 

Survival by PMEPA1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PMEPA1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PMEPA1 56937 14 2 14
GSE20123 PMEPA1 56937 14 2 14
GSE43470 PMEPA1 56937 13 0 30
GSE46452 PMEPA1 56937 29 0 30
GSE47630 PMEPA1 56937 24 1 15
GSE54993 PMEPA1 56937 0 17 53
GSE54994 PMEPA1 56937 29 0 24
GSE60625 PMEPA1 56937 0 0 11
GSE74703 PMEPA1 56937 11 0 25
GSE74704 PMEPA1 56937 11 0 9
TCGA PMEPA1 56937 43 4 49

Total number of gains: 188; Total number of losses: 26; Total Number of normals: 274.  


 

Somatic mutations of PMEPA1:

 

Generating mutation plots.

 

Highly correlated genes for PMEPA1:

 

Showing top 20/746 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PMEPA1INHBA0.85890810010
PMEPA1LOXL20.79927211010
PMEPA1COL5A20.77712511011
PMEPA1COL5A10.77227212011
PMEPA1COL27A10.770881707
PMEPA1TGFBI0.7583112010
PMEPA1BGN0.75542611011
PMEPA1HOMER30.7492611011
PMEPA1CTHRC10.74607707
PMEPA1MFAP20.74519512011
PMEPA1CD2760.739437505
PMEPA1SERPINH10.73652212010
PMEPA1FAP0.735126909
PMEPA1ANXA100.729762303
PMEPA1HTRA10.72974711011
PMEPA1SNAI20.7297361009
PMEPA1PDGFA0.72873511010
PMEPA1ACVR2B0.726907303
PMEPA1LAMB30.723813909
PMEPA1ABCC20.722741303

For details and further investigation, click here