| Full name: melanocortin 2 receptor accessory protein | Alias Symbol: B27|FALP | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 56246 | HGNC ID: HGNC:1304 | Ensembl Gene: ENSG00000170262 | OMIM ID: 609196 |
| Drug and gene relationship at DGIdb | |||
Expression of MRAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRAP | 56246 | 1554044_a_at | -0.1977 | 0.3968 | |
| GSE26886 | MRAP | 56246 | 1554044_a_at | 0.0765 | 0.4601 | |
| GSE45670 | MRAP | 56246 | 1554044_a_at | 0.1957 | 0.2360 | |
| GSE53622 | MRAP | 56246 | 23645 | 0.1581 | 0.2000 | |
| GSE53624 | MRAP | 56246 | 23645 | 0.5153 | 0.0000 | |
| GSE63941 | MRAP | 56246 | 1554044_a_at | -0.0624 | 0.7043 | |
| GSE77861 | MRAP | 56246 | 1555740_a_at | 0.0010 | 0.9932 | |
| GSE97050 | MRAP | 56246 | A_23_P381172 | 0.3008 | 0.1919 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRAP | 56246 | 2 | 10 | 18 | |
| GSE20123 | MRAP | 56246 | 2 | 10 | 18 | |
| GSE43470 | MRAP | 56246 | 3 | 7 | 33 | |
| GSE46452 | MRAP | 56246 | 1 | 21 | 37 | |
| GSE47630 | MRAP | 56246 | 6 | 17 | 17 | |
| GSE54993 | MRAP | 56246 | 9 | 1 | 60 | |
| GSE54994 | MRAP | 56246 | 1 | 8 | 44 | |
| GSE60625 | MRAP | 56246 | 0 | 0 | 11 | |
| GSE74703 | MRAP | 56246 | 3 | 5 | 28 | |
| GSE74704 | MRAP | 56246 | 1 | 6 | 13 | |
| TCGA | MRAP | 56246 | 9 | 36 | 51 |
Total number of gains: 37; Total number of losses: 121; Total Number of normals: 330.
Somatic mutations of MRAP:
Generating mutation plots.
Highly correlated genes for MRAP:
Showing top 20/95 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRAP | SNAI1 | 0.72895 | 3 | 0 | 3 |
| MRAP | CACNG4 | 0.719477 | 4 | 0 | 3 |
| MRAP | TMEM190 | 0.708343 | 3 | 0 | 3 |
| MRAP | ARHGDIG | 0.708326 | 4 | 0 | 3 |
| MRAP | C20orf173 | 0.706217 | 3 | 0 | 3 |
| MRAP | SLC6A13 | 0.697438 | 3 | 0 | 3 |
| MRAP | CD300LG | 0.695816 | 3 | 0 | 3 |
| MRAP | PIWIL2 | 0.680433 | 3 | 0 | 3 |
| MRAP | GP9 | 0.678129 | 4 | 0 | 3 |
| MRAP | SRPK3 | 0.676426 | 3 | 0 | 3 |
| MRAP | ACR | 0.670937 | 3 | 0 | 3 |
| MRAP | GRIK5 | 0.665286 | 3 | 0 | 3 |
| MRAP | MUC8 | 0.66355 | 4 | 0 | 3 |
| MRAP | SLC22A8 | 0.66094 | 4 | 0 | 3 |
| MRAP | PNPLA2 | 0.660892 | 3 | 0 | 3 |
| MRAP | OSM | 0.658109 | 4 | 0 | 3 |
| MRAP | THEG | 0.652349 | 3 | 0 | 3 |
| MRAP | SLC5A5 | 0.652019 | 4 | 0 | 3 |
| MRAP | C10orf90 | 0.651573 | 3 | 0 | 3 |
| MRAP | OR4D2 | 0.64359 | 4 | 0 | 3 |
For details and further investigation, click here
