| Full name: spermatogenesis associated 6 | Alias Symbol: SRF1|FLJ10007|SRF-1 | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 54558 | HGNC ID: HGNC:18309 | Ensembl Gene: ENSG00000132122 | OMIM ID: 613947 |
| Drug and gene relationship at DGIdb | |||
Expression of SPATA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATA6 | 54558 | 242086_at | -0.8996 | 0.3854 | |
| GSE20347 | SPATA6 | 54558 | 220299_at | -0.0168 | 0.8725 | |
| GSE23400 | SPATA6 | 54558 | 220299_at | -0.1291 | 0.0035 | |
| GSE26886 | SPATA6 | 54558 | 242086_at | -0.7722 | 0.0014 | |
| GSE29001 | SPATA6 | 54558 | 220299_at | -0.2487 | 0.4301 | |
| GSE38129 | SPATA6 | 54558 | 220299_at | -0.1663 | 0.1643 | |
| GSE45670 | SPATA6 | 54558 | 242086_at | -1.4303 | 0.0000 | |
| GSE53622 | SPATA6 | 54558 | 100396 | -1.0486 | 0.0000 | |
| GSE53624 | SPATA6 | 54558 | 100396 | -0.9560 | 0.0000 | |
| GSE63941 | SPATA6 | 54558 | 220299_at | -0.0195 | 0.9842 | |
| GSE77861 | SPATA6 | 54558 | 220299_at | -0.0002 | 0.9984 | |
| GSE97050 | SPATA6 | 54558 | A_23_P327483 | -0.0962 | 0.8217 | |
| SRP007169 | SPATA6 | 54558 | RNAseq | -1.5370 | 0.0247 | |
| SRP064894 | SPATA6 | 54558 | RNAseq | -0.6799 | 0.0098 | |
| SRP133303 | SPATA6 | 54558 | RNAseq | -0.8628 | 0.0001 | |
| SRP159526 | SPATA6 | 54558 | RNAseq | -0.3544 | 0.4733 | |
| SRP193095 | SPATA6 | 54558 | RNAseq | -1.0207 | 0.0001 | |
| SRP219564 | SPATA6 | 54558 | RNAseq | -0.6821 | 0.2670 | |
| TCGA | SPATA6 | 54558 | RNAseq | -0.8867 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SPATA6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPATA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATA6 | 54558 | 3 | 3 | 24 | |
| GSE20123 | SPATA6 | 54558 | 3 | 2 | 25 | |
| GSE43470 | SPATA6 | 54558 | 5 | 3 | 35 | |
| GSE46452 | SPATA6 | 54558 | 2 | 1 | 56 | |
| GSE47630 | SPATA6 | 54558 | 8 | 4 | 28 | |
| GSE54993 | SPATA6 | 54558 | 0 | 1 | 69 | |
| GSE54994 | SPATA6 | 54558 | 11 | 2 | 40 | |
| GSE60625 | SPATA6 | 54558 | 0 | 0 | 11 | |
| GSE74703 | SPATA6 | 54558 | 4 | 2 | 30 | |
| GSE74704 | SPATA6 | 54558 | 2 | 0 | 18 | |
| TCGA | SPATA6 | 54558 | 11 | 17 | 68 |
Total number of gains: 49; Total number of losses: 35; Total Number of normals: 404.
Somatic mutations of SPATA6:
Generating mutation plots.
Highly correlated genes for SPATA6:
Showing top 20/1175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATA6 | PARD3B | 0.793478 | 4 | 0 | 4 |
| SPATA6 | DLD | 0.781983 | 3 | 0 | 3 |
| SPATA6 | DISP1 | 0.777801 | 4 | 0 | 4 |
| SPATA6 | CDC26 | 0.767164 | 3 | 0 | 3 |
| SPATA6 | FIBIN | 0.754176 | 3 | 0 | 3 |
| SPATA6 | C1QTNF7 | 0.752866 | 5 | 0 | 5 |
| SPATA6 | LINC01279 | 0.747641 | 3 | 0 | 3 |
| SPATA6 | GALNT11 | 0.743573 | 3 | 0 | 3 |
| SPATA6 | ANO5 | 0.742897 | 5 | 0 | 5 |
| SPATA6 | GPIHBP1 | 0.740599 | 3 | 0 | 3 |
| SPATA6 | ZBTB26 | 0.735195 | 3 | 0 | 3 |
| SPATA6 | ILDR2 | 0.732521 | 3 | 0 | 3 |
| SPATA6 | MAATS1 | 0.727787 | 4 | 0 | 4 |
| SPATA6 | NEGR1 | 0.727605 | 5 | 0 | 5 |
| SPATA6 | FBXL3 | 0.726805 | 4 | 0 | 4 |
| SPATA6 | ANGPTL1 | 0.726225 | 5 | 0 | 5 |
| SPATA6 | NUB1 | 0.725295 | 3 | 0 | 3 |
| SPATA6 | CRNKL1 | 0.720567 | 3 | 0 | 3 |
| SPATA6 | OGN | 0.717057 | 6 | 0 | 6 |
| SPATA6 | SLTM | 0.716568 | 5 | 0 | 5 |
For details and further investigation, click here
