| Full name: glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 | Alias Symbol: LOC338328|GPI-HBP1 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 338328 | HGNC ID: HGNC:24945 | Ensembl Gene: ENSG00000277494 | OMIM ID: 612757 |
| Drug and gene relationship at DGIdb | |||
Expression of GPIHBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPIHBP1 | 338328 | 238062_at | -0.4090 | 0.1694 | |
| GSE26886 | GPIHBP1 | 338328 | 238062_at | -0.0767 | 0.4309 | |
| GSE45670 | GPIHBP1 | 338328 | 238062_at | -0.4812 | 0.0000 | |
| GSE53622 | GPIHBP1 | 338328 | 40728 | 0.1450 | 0.1547 | |
| GSE53624 | GPIHBP1 | 338328 | 40728 | -0.0464 | 0.5937 | |
| GSE63941 | GPIHBP1 | 338328 | 238062_at | 0.1211 | 0.5042 | |
| GSE77861 | GPIHBP1 | 338328 | 238062_at | -0.1047 | 0.3330 | |
| GSE97050 | GPIHBP1 | 338328 | A_23_P72697 | 0.2684 | 0.2385 | |
| SRP064894 | GPIHBP1 | 338328 | RNAseq | -1.6911 | 0.0000 | |
| SRP133303 | GPIHBP1 | 338328 | RNAseq | -1.9408 | 0.0000 | |
| SRP159526 | GPIHBP1 | 338328 | RNAseq | -1.7187 | 0.0103 | |
| SRP219564 | GPIHBP1 | 338328 | RNAseq | -0.7138 | 0.3999 | |
| TCGA | GPIHBP1 | 338328 | RNAseq | -1.8922 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by GPIHBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPIHBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPIHBP1 | 338328 | 17 | 1 | 12 | |
| GSE20123 | GPIHBP1 | 338328 | 17 | 1 | 12 | |
| GSE43470 | GPIHBP1 | 338328 | 17 | 2 | 24 | |
| GSE46452 | GPIHBP1 | 338328 | 27 | 0 | 32 | |
| GSE47630 | GPIHBP1 | 338328 | 23 | 1 | 16 | |
| GSE54993 | GPIHBP1 | 338328 | 0 | 25 | 45 | |
| GSE54994 | GPIHBP1 | 338328 | 39 | 1 | 13 | |
| GSE60625 | GPIHBP1 | 338328 | 3 | 4 | 4 | |
| GSE74703 | GPIHBP1 | 338328 | 15 | 1 | 20 | |
| GSE74704 | GPIHBP1 | 338328 | 10 | 0 | 10 | |
| TCGA | GPIHBP1 | 338328 | 64 | 2 | 30 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of GPIHBP1:
Generating mutation plots.
Highly correlated genes for GPIHBP1:
Showing top 20/412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPIHBP1 | SLC16A4 | 0.8557 | 3 | 0 | 3 |
| GPIHBP1 | SPRY1 | 0.839028 | 3 | 0 | 3 |
| GPIHBP1 | IGF1 | 0.806057 | 4 | 0 | 4 |
| GPIHBP1 | PEG3 | 0.802481 | 3 | 0 | 3 |
| GPIHBP1 | ZBTB16 | 0.786922 | 3 | 0 | 3 |
| GPIHBP1 | EFEMP1 | 0.785834 | 3 | 0 | 3 |
| GPIHBP1 | EZH1 | 0.777389 | 3 | 0 | 3 |
| GPIHBP1 | KCNAB1 | 0.775452 | 3 | 0 | 3 |
| GPIHBP1 | CD63 | 0.774698 | 3 | 0 | 3 |
| GPIHBP1 | AOX1 | 0.771362 | 3 | 0 | 3 |
| GPIHBP1 | FCGRT | 0.768889 | 3 | 0 | 3 |
| GPIHBP1 | ASPA | 0.768141 | 3 | 0 | 3 |
| GPIHBP1 | SYNE1 | 0.767721 | 3 | 0 | 3 |
| GPIHBP1 | KCNT2 | 0.767508 | 3 | 0 | 3 |
| GPIHBP1 | FAM8A1 | 0.766263 | 3 | 0 | 3 |
| GPIHBP1 | KLF2 | 0.765897 | 3 | 0 | 3 |
| GPIHBP1 | TGFBR3 | 0.761385 | 3 | 0 | 3 |
| GPIHBP1 | CLU | 0.757236 | 3 | 0 | 3 |
| GPIHBP1 | FGF7 | 0.757075 | 4 | 0 | 3 |
| GPIHBP1 | SYTL4 | 0.753983 | 3 | 0 | 3 |
For details and further investigation, click here
