| Full name: crooked neck pre-mRNA splicing factor 1 | Alias Symbol: CRN|CLF|SYF3|Clf1 | ||
| Type: protein-coding gene | Cytoband: 20p11.23 | ||
| Entrez ID: 51340 | HGNC ID: HGNC:15762 | Ensembl Gene: ENSG00000101343 | OMIM ID: 610952 |
| Drug and gene relationship at DGIdb | |||
Expression of CRNKL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRNKL1 | 51340 | 219913_s_at | 0.4091 | 0.5948 | |
| GSE20347 | CRNKL1 | 51340 | 219913_s_at | -0.0492 | 0.8618 | |
| GSE23400 | CRNKL1 | 51340 | 219913_s_at | -0.0097 | 0.8917 | |
| GSE26886 | CRNKL1 | 51340 | 219913_s_at | -1.2651 | 0.0005 | |
| GSE29001 | CRNKL1 | 51340 | 219913_s_at | 0.1829 | 0.7037 | |
| GSE38129 | CRNKL1 | 51340 | 219913_s_at | 0.0341 | 0.8726 | |
| GSE45670 | CRNKL1 | 51340 | 219913_s_at | 0.2271 | 0.2216 | |
| GSE53622 | CRNKL1 | 51340 | 40972 | 0.0599 | 0.3188 | |
| GSE53624 | CRNKL1 | 51340 | 40972 | 0.0499 | 0.4357 | |
| GSE63941 | CRNKL1 | 51340 | 219913_s_at | -0.3475 | 0.5077 | |
| GSE77861 | CRNKL1 | 51340 | 219913_s_at | 0.0254 | 0.9314 | |
| GSE97050 | CRNKL1 | 51340 | A_24_P40229 | 0.1306 | 0.7134 | |
| SRP007169 | CRNKL1 | 51340 | RNAseq | 0.2275 | 0.5754 | |
| SRP008496 | CRNKL1 | 51340 | RNAseq | 0.4181 | 0.1452 | |
| SRP064894 | CRNKL1 | 51340 | RNAseq | -0.0081 | 0.9588 | |
| SRP133303 | CRNKL1 | 51340 | RNAseq | -0.0608 | 0.5636 | |
| SRP159526 | CRNKL1 | 51340 | RNAseq | 0.1193 | 0.5669 | |
| SRP193095 | CRNKL1 | 51340 | RNAseq | -0.2709 | 0.0258 | |
| SRP219564 | CRNKL1 | 51340 | RNAseq | -0.5510 | 0.0465 | |
| TCGA | CRNKL1 | 51340 | RNAseq | 0.0422 | 0.4112 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CRNKL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRNKL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRNKL1 | 51340 | 13 | 2 | 15 | |
| GSE20123 | CRNKL1 | 51340 | 13 | 2 | 15 | |
| GSE43470 | CRNKL1 | 51340 | 11 | 1 | 31 | |
| GSE46452 | CRNKL1 | 51340 | 27 | 1 | 31 | |
| GSE47630 | CRNKL1 | 51340 | 17 | 4 | 19 | |
| GSE54993 | CRNKL1 | 51340 | 0 | 15 | 55 | |
| GSE54994 | CRNKL1 | 51340 | 26 | 2 | 25 | |
| GSE60625 | CRNKL1 | 51340 | 0 | 0 | 11 | |
| GSE74703 | CRNKL1 | 51340 | 8 | 1 | 27 | |
| GSE74704 | CRNKL1 | 51340 | 7 | 2 | 11 | |
| TCGA | CRNKL1 | 51340 | 43 | 11 | 42 |
Total number of gains: 165; Total number of losses: 41; Total Number of normals: 282.
Somatic mutations of CRNKL1:
Generating mutation plots.
Highly correlated genes for CRNKL1:
Showing top 20/483 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRNKL1 | RNF34 | 0.81471 | 3 | 0 | 3 |
| CRNKL1 | ARFGAP2 | 0.780235 | 3 | 0 | 3 |
| CRNKL1 | USP24 | 0.776286 | 3 | 0 | 3 |
| CRNKL1 | SAE1 | 0.773734 | 3 | 0 | 3 |
| CRNKL1 | SGMS1 | 0.771542 | 3 | 0 | 3 |
| CRNKL1 | PIGA | 0.768176 | 3 | 0 | 3 |
| CRNKL1 | WWP1 | 0.763192 | 3 | 0 | 3 |
| CRNKL1 | GLYR1 | 0.757912 | 3 | 0 | 3 |
| CRNKL1 | ZFP3 | 0.749665 | 3 | 0 | 3 |
| CRNKL1 | ANKMY2 | 0.744149 | 3 | 0 | 3 |
| CRNKL1 | RBM18 | 0.742823 | 3 | 0 | 3 |
| CRNKL1 | ITPRIPL2 | 0.741329 | 4 | 0 | 4 |
| CRNKL1 | PRDM10 | 0.739176 | 3 | 0 | 3 |
| CRNKL1 | HDAC3 | 0.738857 | 3 | 0 | 3 |
| CRNKL1 | METTL14 | 0.73633 | 3 | 0 | 3 |
| CRNKL1 | TATDN2 | 0.730939 | 3 | 0 | 3 |
| CRNKL1 | TEX261 | 0.726909 | 3 | 0 | 3 |
| CRNKL1 | LRMP | 0.726647 | 3 | 0 | 3 |
| CRNKL1 | IREB2 | 0.726215 | 3 | 0 | 3 |
| CRNKL1 | IFIT5 | 0.722167 | 3 | 0 | 3 |
For details and further investigation, click here
