STAG1

 

Full name: stromal antigen 1 Alias Symbol: SA-1|SCC3A|SA1
Type: protein-coding gene Cytoband: 3q22.3
Entrez ID: 10274 HGNC ID: HGNC:11354 Ensembl Gene: ENSG00000118007 OMIM ID: 604358
Drug and gene relationship at DGIdb
Screen Evidence:

 

STAG1 involved pathways:

KEGG pathway Description View
hsa04110Cell cycle

 

Expression of STAG1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STAG1 10274 202293_at 0.2986 0.3055
GSE20347 STAG1 10274 202294_at 0.1701 0.2861
GSE23400 STAG1 10274 202294_at 0.2315 0.0035
GSE26886 STAG1 10274 202294_at 0.5050 0.0273
GSE29001 STAG1 10274 202294_at 0.3543 0.2440
GSE38129 STAG1 10274 202294_at 0.0446 0.7724
GSE45670 STAG1 10274 202294_at -0.1998 0.2496
GSE53622 STAG1 10274 114115 0.3188 0.0000
GSE53624 STAG1 10274 114115 0.4540 0.0015
GSE63941 STAG1 10274 202293_at -0.4815 0.3731
GSE77861 STAG1 10274 202294_at 0.0541 0.8769
GSE97050 STAG1 10274 A_23_P357365 0.2469 0.3948
SRP007169 STAG1 10274 RNAseq 0.2186 0.5821
SRP008496 STAG1 10274 RNAseq 0.5793 0.0233
SRP064894 STAG1 10274 RNAseq 0.2936 0.1180
SRP133303 STAG1 10274 RNAseq 0.3872 0.0052
SRP159526 STAG1 10274 RNAseq 0.2519 0.4852
SRP193095 STAG1 10274 RNAseq 0.3461 0.0007
SRP219564 STAG1 10274 RNAseq 0.1665 0.3047
TCGA STAG1 10274 RNAseq 0.0768 0.1901

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by STAG1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of STAG1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STAG1 10274 16 0 14
GSE20123 STAG1 10274 16 0 14
GSE43470 STAG1 10274 22 0 21
GSE46452 STAG1 10274 15 4 40
GSE47630 STAG1 10274 18 3 19
GSE54993 STAG1 10274 2 8 60
GSE54994 STAG1 10274 32 1 20
GSE60625 STAG1 10274 0 6 5
GSE74703 STAG1 10274 19 0 17
GSE74704 STAG1 10274 11 0 9
TCGA STAG1 10274 59 5 32

Total number of gains: 210; Total number of losses: 27; Total Number of normals: 251.  


 

Somatic mutations of STAG1:

 

Generating mutation plots.

 

Highly correlated genes for STAG1:

 

Showing top 20/717 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STAG1RRP1B0.815626303
STAG1CENPBD10.804069303
STAG1ZDHHC60.780984303
STAG1PTBP10.776813303
STAG1AP1AR0.767503404
STAG1C12orf730.759431303
STAG1ELF40.750505303
STAG1PSMD30.749122303
STAG1ZSCAN290.746679303
STAG1CCNJ0.735957403
STAG1SPATA20.732092403
STAG1UHRF1BP10.730929404
STAG1SNW10.729868303
STAG1ZBTB390.725629303
STAG1GLIS30.724151303
STAG1TEX100.721553303
STAG1TDRD50.719821303
STAG1JKAMP0.719729404
STAG1ZCCHC30.717463303
STAG1PIGM0.715787403

For details and further investigation, click here