TDRD5

 

Full name: tudor domain containing 5 Alias Symbol: FLJ34823|TUDOR3
Type: protein-coding gene Cytoband: 1q25.2
Entrez ID: 163589 HGNC ID: HGNC:20614 Ensembl Gene: ENSG00000162782 OMIM ID: 617748
Drug and gene relationship at DGIdb

 

Expression of TDRD5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TDRD5 163589 231104_at 2.8005 0.0086
GSE26886 TDRD5 163589 231104_at 0.9373 0.0004
GSE45670 TDRD5 163589 231104_at 1.0393 0.0423
GSE53622 TDRD5 163589 74796 1.8175 0.0000
GSE53624 TDRD5 163589 74796 1.6584 0.0000
GSE63941 TDRD5 163589 231104_at 1.4477 0.1678
GSE77861 TDRD5 163589 231104_at -0.0366 0.8078
GSE97050 TDRD5 163589 A_32_P536872 1.2784 0.1678
SRP007169 TDRD5 163589 RNAseq 2.9591 0.0024
SRP133303 TDRD5 163589 RNAseq 2.9153 0.0001
SRP159526 TDRD5 163589 RNAseq 3.5280 0.0000
TCGA TDRD5 163589 RNAseq 2.2622 0.0000

Upregulated datasets: 8; Downregulated datasets: 0.  


 

Survival by TDRD5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TDRD5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TDRD5 163589 12 0 18
GSE20123 TDRD5 163589 12 0 18
GSE43470 TDRD5 163589 7 1 35
GSE46452 TDRD5 163589 3 1 55
GSE47630 TDRD5 163589 14 0 26
GSE54993 TDRD5 163589 0 6 64
GSE54994 TDRD5 163589 15 0 38
GSE60625 TDRD5 163589 0 0 11
GSE74703 TDRD5 163589 7 1 28
GSE74704 TDRD5 163589 5 0 15
TCGA TDRD5 163589 40 3 53

Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.  


 

Somatic mutations of TDRD5:

 

Generating mutation plots.

 

Highly correlated genes for TDRD5:

 

Showing top 20/541 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TDRD5PTGES0.771633303
TDRD5RGS190.745545303
TDRD5MTHFD10.731841303
TDRD5CFL10.728933303
TDRD5KPNA20.725051303
TDRD5MMACHC0.724394303
TDRD5HSPB110.721456303
TDRD5ELF40.720083303
TDRD5STAG10.719821303
TDRD5CDK5RAP10.714879403
TDRD5DDX210.713417303
TDRD5TIMM90.71339303
TDRD5COMMD70.706475303
TDRD5KIAA09300.706364404
TDRD5DBR10.696172303
TDRD5GPR1580.694979504
TDRD5BRMS10.691574403
TDRD5TMEM2230.688856303
TDRD5NTPCR0.68724303
TDRD5UTP150.684836303

For details and further investigation, click here