| Full name: spermatogenesis associated 2 | Alias Symbol: KIAA0757|PD1|tamo|PPP1R145 | ||
| Type: protein-coding gene | Cytoband: 20q13.13 | ||
| Entrez ID: 9825 | HGNC ID: HGNC:14681 | Ensembl Gene: ENSG00000158480 | OMIM ID: 607662 |
| Drug and gene relationship at DGIdb | |||
Expression of SPATA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATA2 | 9825 | 204433_s_at | 0.9893 | 0.0399 | |
| GSE20347 | SPATA2 | 9825 | 204434_at | 0.0938 | 0.4866 | |
| GSE23400 | SPATA2 | 9825 | 204434_at | -0.0081 | 0.8940 | |
| GSE26886 | SPATA2 | 9825 | 204434_at | -0.1039 | 0.7527 | |
| GSE29001 | SPATA2 | 9825 | 204434_at | 0.3188 | 0.1493 | |
| GSE38129 | SPATA2 | 9825 | 204433_s_at | 0.3658 | 0.0063 | |
| GSE45670 | SPATA2 | 9825 | 204434_at | 0.0959 | 0.6793 | |
| GSE53622 | SPATA2 | 9825 | 42589 | 0.1633 | 0.2571 | |
| GSE53624 | SPATA2 | 9825 | 42589 | 0.2173 | 0.1088 | |
| GSE63941 | SPATA2 | 9825 | 204433_s_at | 0.7442 | 0.0709 | |
| GSE77861 | SPATA2 | 9825 | 204434_at | 0.1837 | 0.3406 | |
| GSE97050 | SPATA2 | 9825 | A_23_P210554 | 0.0745 | 0.7684 | |
| SRP007169 | SPATA2 | 9825 | RNAseq | -0.0588 | 0.8916 | |
| SRP008496 | SPATA2 | 9825 | RNAseq | -0.3764 | 0.2557 | |
| SRP064894 | SPATA2 | 9825 | RNAseq | 0.1410 | 0.3609 | |
| SRP133303 | SPATA2 | 9825 | RNAseq | 0.3198 | 0.0360 | |
| SRP159526 | SPATA2 | 9825 | RNAseq | 0.4985 | 0.2090 | |
| SRP193095 | SPATA2 | 9825 | RNAseq | 0.0637 | 0.6829 | |
| SRP219564 | SPATA2 | 9825 | RNAseq | 0.2710 | 0.3149 | |
| TCGA | SPATA2 | 9825 | RNAseq | 0.0013 | 0.9800 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPATA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPATA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATA2 | 9825 | 17 | 2 | 11 | |
| GSE20123 | SPATA2 | 9825 | 17 | 2 | 11 | |
| GSE43470 | SPATA2 | 9825 | 13 | 0 | 30 | |
| GSE46452 | SPATA2 | 9825 | 29 | 0 | 30 | |
| GSE47630 | SPATA2 | 9825 | 24 | 1 | 15 | |
| GSE54993 | SPATA2 | 9825 | 0 | 17 | 53 | |
| GSE54994 | SPATA2 | 9825 | 27 | 0 | 26 | |
| GSE60625 | SPATA2 | 9825 | 0 | 0 | 11 | |
| GSE74703 | SPATA2 | 9825 | 11 | 0 | 25 | |
| GSE74704 | SPATA2 | 9825 | 13 | 0 | 7 | |
| TCGA | SPATA2 | 9825 | 46 | 3 | 47 |
Total number of gains: 197; Total number of losses: 25; Total Number of normals: 266.
Somatic mutations of SPATA2:
Generating mutation plots.
Highly correlated genes for SPATA2:
Showing top 20/877 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATA2 | KLHL8 | 0.846078 | 3 | 0 | 3 |
| SPATA2 | DYRK2 | 0.821076 | 3 | 0 | 3 |
| SPATA2 | ANKRD27 | 0.798144 | 3 | 0 | 3 |
| SPATA2 | KCTD15 | 0.786417 | 3 | 0 | 3 |
| SPATA2 | LIN9 | 0.784332 | 3 | 0 | 3 |
| SPATA2 | NAA25 | 0.783498 | 3 | 0 | 3 |
| SPATA2 | ZNF644 | 0.783429 | 3 | 0 | 3 |
| SPATA2 | PPAT | 0.769451 | 3 | 0 | 3 |
| SPATA2 | SWT1 | 0.763788 | 3 | 0 | 3 |
| SPATA2 | ZNF418 | 0.757259 | 3 | 0 | 3 |
| SPATA2 | MPHOSPH9 | 0.755327 | 3 | 0 | 3 |
| SPATA2 | ITGB4 | 0.755298 | 3 | 0 | 3 |
| SPATA2 | ZNF668 | 0.753652 | 3 | 0 | 3 |
| SPATA2 | BANF1 | 0.752712 | 3 | 0 | 3 |
| SPATA2 | DDHD1 | 0.751421 | 3 | 0 | 3 |
| SPATA2 | COMMD7 | 0.748459 | 4 | 0 | 4 |
| SPATA2 | GEN1 | 0.744736 | 3 | 0 | 3 |
| SPATA2 | ZNF124 | 0.739191 | 3 | 0 | 3 |
| SPATA2 | RAD1 | 0.738725 | 5 | 0 | 5 |
| SPATA2 | SNX5 | 0.738633 | 4 | 0 | 4 |
For details and further investigation, click here
