PIGM

 

Full name: phosphatidylinositol glycan anchor biosynthesis class M Alias Symbol: GPI-MT-I
Type: protein-coding gene Cytoband: 1q23.2
Entrez ID: 93183 HGNC ID: HGNC:18858 Ensembl Gene: ENSG00000143315 OMIM ID: 610273
Drug and gene relationship at DGIdb

 

Expression of PIGM:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PIGM 93183 223470_at 0.0836 0.8103
GSE26886 PIGM 93183 223470_at -0.2269 0.3154
GSE45670 PIGM 93183 223470_at 0.1319 0.3262
GSE53622 PIGM 93183 36674 0.0313 0.7529
GSE53624 PIGM 93183 36674 0.2424 0.0201
GSE63941 PIGM 93183 223470_at -0.1175 0.7984
GSE77861 PIGM 93183 223470_at 0.0325 0.8975
GSE97050 PIGM 93183 A_33_P3386965 0.1320 0.4907
SRP007169 PIGM 93183 RNAseq -0.0062 0.9880
SRP008496 PIGM 93183 RNAseq 0.3711 0.2464
SRP064894 PIGM 93183 RNAseq -0.0367 0.7609
SRP133303 PIGM 93183 RNAseq 0.0671 0.6717
SRP159526 PIGM 93183 RNAseq 0.5643 0.0054
SRP193095 PIGM 93183 RNAseq 0.0822 0.4142
SRP219564 PIGM 93183 RNAseq 0.2676 0.3961
TCGA PIGM 93183 RNAseq -0.0739 0.2178

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by PIGM expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PIGM:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PIGM 93183 10 0 20
GSE20123 PIGM 93183 10 0 20
GSE43470 PIGM 93183 7 2 34
GSE46452 PIGM 93183 2 1 56
GSE47630 PIGM 93183 15 0 25
GSE54993 PIGM 93183 0 5 65
GSE54994 PIGM 93183 16 0 37
GSE60625 PIGM 93183 0 0 11
GSE74703 PIGM 93183 7 2 27
GSE74704 PIGM 93183 4 0 16
TCGA PIGM 93183 44 3 49

Total number of gains: 115; Total number of losses: 13; Total Number of normals: 360.  


 

Somatic mutations of PIGM:

 

Generating mutation plots.

 

Highly correlated genes for PIGM:

 

Showing top 20/215 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PIGMCOG30.805237303
PIGMRRP1B0.783712303
PIGMLRP110.77453303
PIGMLATS10.762171303
PIGMLRRC470.74484303
PIGMDDX230.740965303
PIGMTADA2A0.739283303
PIGMRNF80.738082303
PIGMALG100.735797303
PIGMANKRD280.735463303
PIGMJKAMP0.732481303
PIGMTYW10.729637303
PIGMGDE10.728346303
PIGMUTP200.72529303
PIGMLUC7L20.725172303
PIGMIFT200.717381303
PIGMSTAG10.715787403
PIGMINTS60.714961303
PIGMCOMMD20.712762303
PIGMTOMM220.710057303

For details and further investigation, click here