| Full name: MIER family member 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 54531 | HGNC ID: HGNC:29210 | Ensembl Gene: ENSG00000105556 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MIER2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIER2 | 54531 | 44822_s_at | 0.5189 | 0.1310 | |
| GSE20347 | MIER2 | 54531 | 44822_s_at | 0.1549 | 0.1428 | |
| GSE23400 | MIER2 | 54531 | 221863_at | -0.0171 | 0.7195 | |
| GSE26886 | MIER2 | 54531 | 44822_s_at | 0.4816 | 0.0018 | |
| GSE29001 | MIER2 | 54531 | 44822_s_at | -0.0393 | 0.9329 | |
| GSE38129 | MIER2 | 54531 | 44822_s_at | 0.1078 | 0.2529 | |
| GSE45670 | MIER2 | 54531 | 44822_s_at | 0.2350 | 0.0623 | |
| GSE63941 | MIER2 | 54531 | 44822_s_at | 0.3159 | 0.2810 | |
| GSE77861 | MIER2 | 54531 | 221863_at | 0.0282 | 0.8338 | |
| GSE97050 | MIER2 | 54531 | A_33_P3227324 | 0.1881 | 0.5328 | |
| SRP007169 | MIER2 | 54531 | RNAseq | -0.5700 | 0.1546 | |
| SRP008496 | MIER2 | 54531 | RNAseq | -0.7449 | 0.0019 | |
| SRP064894 | MIER2 | 54531 | RNAseq | 0.4355 | 0.0302 | |
| SRP133303 | MIER2 | 54531 | RNAseq | 0.1602 | 0.3889 | |
| SRP159526 | MIER2 | 54531 | RNAseq | -0.1079 | 0.6193 | |
| SRP193095 | MIER2 | 54531 | RNAseq | 0.3237 | 0.0017 | |
| SRP219564 | MIER2 | 54531 | RNAseq | 0.4016 | 0.1931 | |
| TCGA | MIER2 | 54531 | RNAseq | 0.1411 | 0.0083 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MIER2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MIER2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIER2 | 54531 | 8 | 6 | 16 | |
| GSE20123 | MIER2 | 54531 | 8 | 5 | 17 | |
| GSE43470 | MIER2 | 54531 | 1 | 10 | 32 | |
| GSE46452 | MIER2 | 54531 | 47 | 1 | 11 | |
| GSE47630 | MIER2 | 54531 | 5 | 7 | 28 | |
| GSE54993 | MIER2 | 54531 | 13 | 4 | 53 | |
| GSE54994 | MIER2 | 54531 | 8 | 15 | 30 | |
| GSE60625 | MIER2 | 54531 | 9 | 0 | 2 | |
| GSE74703 | MIER2 | 54531 | 1 | 7 | 28 | |
| GSE74704 | MIER2 | 54531 | 7 | 3 | 10 | |
| TCGA | MIER2 | 54531 | 8 | 26 | 62 |
Total number of gains: 115; Total number of losses: 84; Total Number of normals: 289.
Somatic mutations of MIER2:
Generating mutation plots.
Highly correlated genes for MIER2:
Showing top 20/892 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIER2 | CYHR1 | 0.824552 | 3 | 0 | 3 |
| MIER2 | PTPN23 | 0.815577 | 3 | 0 | 3 |
| MIER2 | EPN1 | 0.802485 | 5 | 0 | 5 |
| MIER2 | GOSR1 | 0.785059 | 3 | 0 | 3 |
| MIER2 | ADAM22 | 0.7796 | 3 | 0 | 3 |
| MIER2 | CLEC11A | 0.77887 | 3 | 0 | 3 |
| MIER2 | NUP43 | 0.768645 | 3 | 0 | 3 |
| MIER2 | TP53I11 | 0.76313 | 5 | 0 | 5 |
| MIER2 | PPP1R37 | 0.760807 | 4 | 0 | 4 |
| MIER2 | OAF | 0.760442 | 3 | 0 | 3 |
| MIER2 | TMEM97 | 0.755048 | 3 | 0 | 3 |
| MIER2 | ISM2 | 0.748444 | 3 | 0 | 3 |
| MIER2 | SUGP2 | 0.747324 | 3 | 0 | 3 |
| MIER2 | ARHGEF11 | 0.746423 | 4 | 0 | 4 |
| MIER2 | ANP32B | 0.745459 | 3 | 0 | 3 |
| MIER2 | PSMB1 | 0.743944 | 3 | 0 | 3 |
| MIER2 | KCNC4 | 0.743528 | 4 | 0 | 4 |
| MIER2 | B3GALT6 | 0.743523 | 3 | 0 | 3 |
| MIER2 | ARF1 | 0.73915 | 3 | 0 | 3 |
| MIER2 | NAGLU | 0.737138 | 3 | 0 | 3 |
For details and further investigation, click here
