| Full name: TATA-box binding protein associated factor 15 | Alias Symbol: hTAFII68|RBP56|Npl3 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 8148 | HGNC ID: HGNC:11547 | Ensembl Gene: ENSG00000270647 | OMIM ID: 601574 |
| Drug and gene relationship at DGIdb | |||
Expression of TAF15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF15 | 8148 | 202840_at | 0.0331 | 0.9304 | |
| GSE20347 | TAF15 | 8148 | 202840_at | -0.0914 | 0.5734 | |
| GSE23400 | TAF15 | 8148 | 202840_at | -0.0063 | 0.9249 | |
| GSE26886 | TAF15 | 8148 | 202840_at | -0.6093 | 0.0137 | |
| GSE29001 | TAF15 | 8148 | 202840_at | -0.1701 | 0.7024 | |
| GSE38129 | TAF15 | 8148 | 202840_at | 0.0923 | 0.7351 | |
| GSE45670 | TAF15 | 8148 | 227891_s_at | 0.0169 | 0.9388 | |
| GSE53622 | TAF15 | 8148 | 11614 | -0.3176 | 0.0000 | |
| GSE53624 | TAF15 | 8148 | 11614 | -0.4847 | 0.0000 | |
| GSE63941 | TAF15 | 8148 | 202840_at | 0.6048 | 0.0559 | |
| GSE77861 | TAF15 | 8148 | 202840_at | 0.0414 | 0.8699 | |
| GSE97050 | TAF15 | 8148 | A_23_P159305 | -0.1437 | 0.4740 | |
| SRP007169 | TAF15 | 8148 | RNAseq | 1.2021 | 0.0238 | |
| SRP008496 | TAF15 | 8148 | RNAseq | 0.7608 | 0.0541 | |
| SRP064894 | TAF15 | 8148 | RNAseq | 0.1040 | 0.5460 | |
| SRP133303 | TAF15 | 8148 | RNAseq | -0.0845 | 0.5178 | |
| SRP159526 | TAF15 | 8148 | RNAseq | -0.1751 | 0.2632 | |
| SRP193095 | TAF15 | 8148 | RNAseq | -0.0870 | 0.5167 | |
| SRP219564 | TAF15 | 8148 | RNAseq | -0.3817 | 0.2246 | |
| TCGA | TAF15 | 8148 | RNAseq | 0.0558 | 0.2039 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TAF15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF15 | 8148 | 5 | 1 | 24 | |
| GSE20123 | TAF15 | 8148 | 5 | 1 | 24 | |
| GSE43470 | TAF15 | 8148 | 1 | 2 | 40 | |
| GSE46452 | TAF15 | 8148 | 34 | 0 | 25 | |
| GSE47630 | TAF15 | 8148 | 7 | 1 | 32 | |
| GSE54993 | TAF15 | 8148 | 3 | 3 | 64 | |
| GSE54994 | TAF15 | 8148 | 8 | 6 | 39 | |
| GSE60625 | TAF15 | 8148 | 4 | 0 | 7 | |
| GSE74703 | TAF15 | 8148 | 1 | 1 | 34 | |
| GSE74704 | TAF15 | 8148 | 3 | 1 | 16 | |
| TCGA | TAF15 | 8148 | 20 | 9 | 67 |
Total number of gains: 91; Total number of losses: 25; Total Number of normals: 372.
Somatic mutations of TAF15:
Generating mutation plots.
Highly correlated genes for TAF15:
Showing top 20/130 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF15 | ANKRD27 | 0.768132 | 3 | 0 | 3 |
| TAF15 | RSF1 | 0.752806 | 3 | 0 | 3 |
| TAF15 | DCAF16 | 0.749948 | 3 | 0 | 3 |
| TAF15 | MCOLN1 | 0.745714 | 3 | 0 | 3 |
| TAF15 | DNAJC7 | 0.743492 | 3 | 0 | 3 |
| TAF15 | ZNF513 | 0.733307 | 3 | 0 | 3 |
| TAF15 | DDX59 | 0.732989 | 3 | 0 | 3 |
| TAF15 | GNAI2 | 0.723896 | 3 | 0 | 3 |
| TAF15 | NOMO3 | 0.721064 | 3 | 0 | 3 |
| TAF15 | SUGP2 | 0.71849 | 4 | 0 | 3 |
| TAF15 | SF3A2 | 0.715723 | 4 | 0 | 4 |
| TAF15 | ZNF502 | 0.71229 | 3 | 0 | 3 |
| TAF15 | ZNF787 | 0.709831 | 4 | 0 | 4 |
| TAF15 | ZNF577 | 0.705924 | 3 | 0 | 3 |
| TAF15 | C5orf51 | 0.70443 | 3 | 0 | 3 |
| TAF15 | PHF2 | 0.700485 | 4 | 0 | 3 |
| TAF15 | NEK9 | 0.693532 | 3 | 0 | 3 |
| TAF15 | FIP1L1 | 0.690285 | 4 | 0 | 3 |
| TAF15 | ZSCAN29 | 0.690279 | 3 | 0 | 3 |
| TAF15 | PPP3R1 | 0.681745 | 3 | 0 | 3 |
For details and further investigation, click here
