| Full name: NADH:ubiquinone oxidoreductase subunit A3 | Alias Symbol: B9 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 4696 | HGNC ID: HGNC:7686 | Ensembl Gene: ENSG00000170906 | OMIM ID: 603832 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NDUFA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFA3 | 4696 | 218563_at | 0.1172 | 0.8553 | |
| GSE20347 | NDUFA3 | 4696 | 218563_at | -0.5933 | 0.0000 | |
| GSE23400 | NDUFA3 | 4696 | 218563_at | -0.3126 | 0.0048 | |
| GSE26886 | NDUFA3 | 4696 | 218563_at | 0.1841 | 0.3258 | |
| GSE29001 | NDUFA3 | 4696 | 218563_at | -0.6530 | 0.0062 | |
| GSE38129 | NDUFA3 | 4696 | 218563_at | -0.4467 | 0.0000 | |
| GSE45670 | NDUFA3 | 4696 | 218563_at | -0.2204 | 0.0996 | |
| GSE53622 | NDUFA3 | 4696 | 61610 | -0.1915 | 0.0012 | |
| GSE53624 | NDUFA3 | 4696 | 61610 | -0.1221 | 0.0077 | |
| GSE63941 | NDUFA3 | 4696 | 218563_at | 0.1994 | 0.6039 | |
| GSE77861 | NDUFA3 | 4696 | 218563_at | -0.5965 | 0.0120 | |
| GSE97050 | NDUFA3 | 4696 | A_23_P208540 | -0.0485 | 0.8328 | |
| SRP007169 | NDUFA3 | 4696 | RNAseq | -0.5977 | 0.3602 | |
| SRP064894 | NDUFA3 | 4696 | RNAseq | 0.4766 | 0.3317 | |
| SRP133303 | NDUFA3 | 4696 | RNAseq | -0.0751 | 0.5292 | |
| SRP159526 | NDUFA3 | 4696 | RNAseq | 0.0739 | 0.7863 | |
| SRP193095 | NDUFA3 | 4696 | RNAseq | -0.4148 | 0.0004 | |
| SRP219564 | NDUFA3 | 4696 | RNAseq | -0.1830 | 0.5964 | |
| TCGA | NDUFA3 | 4696 | RNAseq | -0.1713 | 0.0254 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFA3 | 4696 | 3 | 4 | 23 | |
| GSE20123 | NDUFA3 | 4696 | 3 | 3 | 24 | |
| GSE43470 | NDUFA3 | 4696 | 2 | 11 | 30 | |
| GSE46452 | NDUFA3 | 4696 | 45 | 1 | 13 | |
| GSE47630 | NDUFA3 | 4696 | 8 | 6 | 26 | |
| GSE54993 | NDUFA3 | 4696 | 17 | 4 | 49 | |
| GSE54994 | NDUFA3 | 4696 | 4 | 14 | 35 | |
| GSE60625 | NDUFA3 | 4696 | 9 | 0 | 2 | |
| GSE74703 | NDUFA3 | 4696 | 2 | 7 | 27 | |
| GSE74704 | NDUFA3 | 4696 | 3 | 1 | 16 | |
| TCGA | NDUFA3 | 4696 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 66; Total Number of normals: 307.
Somatic mutations of NDUFA3:
Generating mutation plots.
Highly correlated genes for NDUFA3:
Showing top 20/555 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFA3 | SUGP2 | 0.775462 | 3 | 0 | 3 |
| NDUFA3 | SLC46A2 | 0.762728 | 3 | 0 | 3 |
| NDUFA3 | SCAF1 | 0.758595 | 3 | 0 | 3 |
| NDUFA3 | GBA2 | 0.750622 | 3 | 0 | 3 |
| NDUFA3 | YPEL3 | 0.739966 | 3 | 0 | 3 |
| NDUFA3 | PRRC2A | 0.736657 | 3 | 0 | 3 |
| NDUFA3 | ULK3 | 0.73079 | 3 | 0 | 3 |
| NDUFA3 | GLB1L2 | 0.729931 | 4 | 0 | 4 |
| NDUFA3 | ZNF223 | 0.72785 | 3 | 0 | 3 |
| NDUFA3 | TMEM129 | 0.726832 | 3 | 0 | 3 |
| NDUFA3 | COMTD1 | 0.714193 | 3 | 0 | 3 |
| NDUFA3 | GSK3A | 0.712918 | 5 | 0 | 5 |
| NDUFA3 | CHD3 | 0.712408 | 3 | 0 | 3 |
| NDUFA3 | RALGPS2 | 0.712292 | 3 | 0 | 3 |
| NDUFA3 | BBIP1 | 0.712218 | 4 | 0 | 4 |
| NDUFA3 | SUFU | 0.703324 | 3 | 0 | 3 |
| NDUFA3 | INTS6 | 0.702724 | 3 | 0 | 3 |
| NDUFA3 | SLC25A29 | 0.70214 | 3 | 0 | 3 |
| NDUFA3 | SGSH | 0.695375 | 3 | 0 | 3 |
| NDUFA3 | MBNL3 | 0.694448 | 4 | 0 | 4 |
For details and further investigation, click here
