| Full name: synaptic vesicle glycoprotein 2C | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q13.3 | ||
| Entrez ID: 22987 | HGNC ID: HGNC:30670 | Ensembl Gene: ENSG00000122012 | OMIM ID: 610291 |
| Drug and gene relationship at DGIdb | |||
Expression of SV2C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SV2C | 22987 | 216086_at | -0.1107 | 0.6244 | |
| GSE20347 | SV2C | 22987 | 216086_at | -0.0391 | 0.5368 | |
| GSE23400 | SV2C | 22987 | 216086_at | -0.0578 | 0.0244 | |
| GSE26886 | SV2C | 22987 | 1562372_at | -0.1898 | 0.0672 | |
| GSE29001 | SV2C | 22987 | 216086_at | 0.0051 | 0.9785 | |
| GSE38129 | SV2C | 22987 | 216086_at | -0.1292 | 0.0347 | |
| GSE45670 | SV2C | 22987 | 1562372_at | 0.0374 | 0.6574 | |
| GSE53622 | SV2C | 22987 | 113942 | -0.2248 | 0.0009 | |
| GSE53624 | SV2C | 22987 | 113942 | -0.4341 | 0.0000 | |
| GSE63941 | SV2C | 22987 | 1562372_at | 0.1686 | 0.1632 | |
| GSE77861 | SV2C | 22987 | 1562372_at | -0.0312 | 0.7894 | |
| GSE97050 | SV2C | 22987 | A_33_P3314301 | -0.0657 | 0.7423 | |
| SRP133303 | SV2C | 22987 | RNAseq | -0.4046 | 0.1085 | |
| SRP159526 | SV2C | 22987 | RNAseq | 1.0507 | 0.1878 | |
| SRP193095 | SV2C | 22987 | RNAseq | -0.3484 | 0.1601 | |
| TCGA | SV2C | 22987 | RNAseq | -2.9259 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SV2C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SV2C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SV2C | 22987 | 1 | 13 | 16 | |
| GSE20123 | SV2C | 22987 | 1 | 13 | 16 | |
| GSE43470 | SV2C | 22987 | 1 | 13 | 29 | |
| GSE46452 | SV2C | 22987 | 0 | 28 | 31 | |
| GSE47630 | SV2C | 22987 | 1 | 19 | 20 | |
| GSE54993 | SV2C | 22987 | 8 | 1 | 61 | |
| GSE54994 | SV2C | 22987 | 1 | 19 | 33 | |
| GSE60625 | SV2C | 22987 | 0 | 0 | 11 | |
| GSE74703 | SV2C | 22987 | 1 | 9 | 26 | |
| GSE74704 | SV2C | 22987 | 1 | 6 | 13 | |
| TCGA | SV2C | 22987 | 5 | 49 | 42 |
Total number of gains: 20; Total number of losses: 170; Total Number of normals: 298.
Somatic mutations of SV2C:
Generating mutation plots.
Highly correlated genes for SV2C:
Showing top 20/614 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SV2C | RNF157 | 0.77063 | 3 | 0 | 3 |
| SV2C | CIB3 | 0.75806 | 3 | 0 | 3 |
| SV2C | MEPE | 0.751979 | 3 | 0 | 3 |
| SV2C | GABRD | 0.751332 | 3 | 0 | 3 |
| SV2C | LINC00302 | 0.750106 | 3 | 0 | 3 |
| SV2C | STXBP6 | 0.738677 | 3 | 0 | 3 |
| SV2C | KCNJ13 | 0.728314 | 4 | 0 | 4 |
| SV2C | WNT9A | 0.727282 | 3 | 0 | 3 |
| SV2C | AICDA | 0.726569 | 3 | 0 | 3 |
| SV2C | RNF186 | 0.726396 | 3 | 0 | 3 |
| SV2C | C16orf82 | 0.723659 | 3 | 0 | 3 |
| SV2C | ROS1 | 0.721053 | 4 | 0 | 4 |
| SV2C | HTR1A | 0.719419 | 4 | 0 | 4 |
| SV2C | OR2J2 | 0.718718 | 3 | 0 | 3 |
| SV2C | ALDH1L1 | 0.716136 | 3 | 0 | 3 |
| SV2C | EDDM3A | 0.715573 | 4 | 0 | 4 |
| SV2C | TMEM108 | 0.713922 | 3 | 0 | 3 |
| SV2C | KIF17 | 0.713807 | 3 | 0 | 3 |
| SV2C | LYPD4 | 0.709833 | 3 | 0 | 3 |
| SV2C | GRIPAP1 | 0.705636 | 3 | 0 | 3 |
For details and further investigation, click here
