| Full name: ring finger protein 186 | Alias Symbol: FLJ20225 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 54546 | HGNC ID: HGNC:25978 | Ensembl Gene: ENSG00000178828 | OMIM ID: 617163 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF186:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF186 | 54546 | 219739_at | -0.1751 | 0.4014 | |
| GSE20347 | RNF186 | 54546 | 219739_at | -0.0479 | 0.5990 | |
| GSE23400 | RNF186 | 54546 | 219739_at | -0.1024 | 0.0008 | |
| GSE26886 | RNF186 | 54546 | 219739_at | -0.0733 | 0.5277 | |
| GSE29001 | RNF186 | 54546 | 219739_at | -0.1616 | 0.2895 | |
| GSE38129 | RNF186 | 54546 | 219739_at | -0.1409 | 0.1478 | |
| GSE45670 | RNF186 | 54546 | 219739_at | -0.0262 | 0.8310 | |
| GSE53622 | RNF186 | 54546 | 75457 | 0.4438 | 0.0000 | |
| GSE53624 | RNF186 | 54546 | 75457 | 0.4624 | 0.0000 | |
| GSE63941 | RNF186 | 54546 | 219739_at | 0.1052 | 0.4422 | |
| GSE77861 | RNF186 | 54546 | 219739_at | -0.2608 | 0.0991 | |
| GSE97050 | RNF186 | 54546 | A_23_P126248 | -0.1765 | 0.5580 | |
| TCGA | RNF186 | 54546 | RNAseq | -2.3480 | 0.0732 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF186 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF186:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF186 | 54546 | 0 | 5 | 25 | |
| GSE20123 | RNF186 | 54546 | 0 | 4 | 26 | |
| GSE43470 | RNF186 | 54546 | 0 | 8 | 35 | |
| GSE46452 | RNF186 | 54546 | 5 | 1 | 53 | |
| GSE47630 | RNF186 | 54546 | 8 | 3 | 29 | |
| GSE54993 | RNF186 | 54546 | 3 | 1 | 66 | |
| GSE54994 | RNF186 | 54546 | 11 | 4 | 38 | |
| GSE60625 | RNF186 | 54546 | 0 | 0 | 11 | |
| GSE74703 | RNF186 | 54546 | 0 | 5 | 31 | |
| GSE74704 | RNF186 | 54546 | 0 | 0 | 20 | |
| TCGA | RNF186 | 54546 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of RNF186:
Generating mutation plots.
Highly correlated genes for RNF186:
Showing top 20/681 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF186 | HRC | 0.763768 | 4 | 0 | 4 |
| RNF186 | NPM2 | 0.743341 | 3 | 0 | 3 |
| RNF186 | FHIT | 0.729226 | 3 | 0 | 3 |
| RNF186 | SV2C | 0.726396 | 3 | 0 | 3 |
| RNF186 | PTPRN2 | 0.725653 | 5 | 0 | 5 |
| RNF186 | ABCC6 | 0.714358 | 3 | 0 | 3 |
| RNF186 | TMEM125 | 0.713495 | 3 | 0 | 3 |
| RNF186 | ANKRD33B | 0.712221 | 3 | 0 | 3 |
| RNF186 | PSMB11 | 0.70385 | 3 | 0 | 3 |
| RNF186 | CPA2 | 0.70154 | 3 | 0 | 3 |
| RNF186 | PGC | 0.700562 | 4 | 0 | 3 |
| RNF186 | NKX6-3 | 0.698444 | 4 | 0 | 3 |
| RNF186 | C3orf36 | 0.695339 | 5 | 0 | 5 |
| RNF186 | CGA | 0.694701 | 4 | 0 | 4 |
| RNF186 | ART1 | 0.69056 | 4 | 0 | 4 |
| RNF186 | NHLRC4 | 0.686619 | 3 | 0 | 3 |
| RNF186 | OR2C3 | 0.685637 | 3 | 0 | 3 |
| RNF186 | GJD4 | 0.683127 | 4 | 0 | 4 |
| RNF186 | BPIFA1 | 0.683073 | 4 | 0 | 3 |
| RNF186 | IGSF21 | 0.682849 | 3 | 0 | 3 |
For details and further investigation, click here
