| Full name: epididymal protein 3A | Alias Symbol: HE3-ALPHA | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 10876 | HGNC ID: HGNC:16978 | Ensembl Gene: ENSG00000181562 | OMIM ID: 611580 |
| Drug and gene relationship at DGIdb | |||
Expression of EDDM3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EDDM3A | 10876 | 217568_at | -0.1881 | 0.3047 | |
| GSE20347 | EDDM3A | 10876 | 217568_at | 0.0046 | 0.9507 | |
| GSE23400 | EDDM3A | 10876 | 217568_at | -0.0816 | 0.0652 | |
| GSE26886 | EDDM3A | 10876 | 208142_at | -0.0254 | 0.8068 | |
| GSE29001 | EDDM3A | 10876 | 217568_at | -0.1094 | 0.6579 | |
| GSE38129 | EDDM3A | 10876 | 217568_at | -0.0614 | 0.3340 | |
| GSE45670 | EDDM3A | 10876 | 217568_at | 0.1027 | 0.1641 | |
| GSE53622 | EDDM3A | 10876 | 32533 | 0.2489 | 0.1030 | |
| GSE53624 | EDDM3A | 10876 | 32533 | 0.0873 | 0.2744 | |
| GSE63941 | EDDM3A | 10876 | 217568_at | 0.1637 | 0.0522 | |
| GSE77861 | EDDM3A | 10876 | 217568_at | -0.0289 | 0.8159 | |
| TCGA | EDDM3A | 10876 | RNAseq | -1.2737 | 0.4223 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EDDM3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EDDM3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EDDM3A | 10876 | 9 | 3 | 18 | |
| GSE20123 | EDDM3A | 10876 | 8 | 3 | 19 | |
| GSE43470 | EDDM3A | 10876 | 7 | 1 | 35 | |
| GSE46452 | EDDM3A | 10876 | 19 | 2 | 38 | |
| GSE47630 | EDDM3A | 10876 | 10 | 10 | 20 | |
| GSE54993 | EDDM3A | 10876 | 3 | 11 | 56 | |
| GSE54994 | EDDM3A | 10876 | 18 | 5 | 30 | |
| GSE60625 | EDDM3A | 10876 | 0 | 2 | 9 | |
| GSE74703 | EDDM3A | 10876 | 6 | 1 | 29 | |
| GSE74704 | EDDM3A | 10876 | 4 | 2 | 14 | |
| TCGA | EDDM3A | 10876 | 27 | 16 | 53 |
Total number of gains: 111; Total number of losses: 56; Total Number of normals: 321.
Somatic mutations of EDDM3A:
Generating mutation plots.
Highly correlated genes for EDDM3A:
Showing top 20/484 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EDDM3A | CBLN1 | 0.809276 | 4 | 0 | 4 |
| EDDM3A | SYN1 | 0.750199 | 3 | 0 | 3 |
| EDDM3A | TRPV5 | 0.746585 | 3 | 0 | 3 |
| EDDM3A | RHAG | 0.731074 | 3 | 0 | 3 |
| EDDM3A | KRTAP4-7 | 0.722229 | 3 | 0 | 3 |
| EDDM3A | STXBP6 | 0.721695 | 3 | 0 | 3 |
| EDDM3A | PRPS1L1 | 0.721076 | 3 | 0 | 3 |
| EDDM3A | INSL5 | 0.719418 | 3 | 0 | 3 |
| EDDM3A | RNF5 | 0.719042 | 3 | 0 | 3 |
| EDDM3A | SV2C | 0.715573 | 4 | 0 | 4 |
| EDDM3A | BRS3 | 0.71548 | 3 | 0 | 3 |
| EDDM3A | CA5B | 0.709855 | 3 | 0 | 3 |
| EDDM3A | ASIC1 | 0.70584 | 4 | 0 | 4 |
| EDDM3A | PDE6H | 0.705703 | 3 | 0 | 3 |
| EDDM3A | DDX4 | 0.704955 | 3 | 0 | 3 |
| EDDM3A | PRSS58 | 0.704248 | 3 | 0 | 3 |
| EDDM3A | OCM2 | 0.701386 | 3 | 0 | 3 |
| EDDM3A | CDH17 | 0.700427 | 3 | 0 | 3 |
| EDDM3A | PLA2G5 | 0.699883 | 3 | 0 | 3 |
| EDDM3A | HYAL4 | 0.697437 | 4 | 0 | 4 |
For details and further investigation, click here
