| Full name: THAP domain containing 5 | Alias Symbol: DKFZp313O1132 | ||
| Type: protein-coding gene | Cytoband: 7q31.1 | ||
| Entrez ID: 168451 | HGNC ID: HGNC:23188 | Ensembl Gene: ENSG00000177683 | OMIM ID: 612534 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of THAP5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THAP5 | 168451 | 227636_at | 0.2478 | 0.5271 | |
| GSE26886 | THAP5 | 168451 | 227636_at | 0.7425 | 0.0123 | |
| GSE45670 | THAP5 | 168451 | 227636_at | 0.3057 | 0.1452 | |
| GSE53622 | THAP5 | 168451 | 126713 | 0.4179 | 0.0000 | |
| GSE53624 | THAP5 | 168451 | 43052 | 0.3128 | 0.0079 | |
| GSE63941 | THAP5 | 168451 | 227636_at | -0.4432 | 0.3250 | |
| GSE77861 | THAP5 | 168451 | 227636_at | 0.7477 | 0.0094 | |
| GSE97050 | THAP5 | 168451 | A_24_P23522 | 0.3549 | 0.2025 | |
| SRP007169 | THAP5 | 168451 | RNAseq | -0.0621 | 0.8697 | |
| SRP008496 | THAP5 | 168451 | RNAseq | 0.0623 | 0.7887 | |
| SRP064894 | THAP5 | 168451 | RNAseq | 0.3004 | 0.0153 | |
| SRP133303 | THAP5 | 168451 | RNAseq | 0.4966 | 0.0054 | |
| SRP159526 | THAP5 | 168451 | RNAseq | 0.3466 | 0.1038 | |
| SRP193095 | THAP5 | 168451 | RNAseq | 0.3178 | 0.0043 | |
| SRP219564 | THAP5 | 168451 | RNAseq | 0.2195 | 0.4592 | |
| TCGA | THAP5 | 168451 | RNAseq | -0.0419 | 0.4988 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THAP5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THAP5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THAP5 | 168451 | 11 | 0 | 19 | |
| GSE20123 | THAP5 | 168451 | 11 | 0 | 19 | |
| GSE43470 | THAP5 | 168451 | 7 | 1 | 35 | |
| GSE46452 | THAP5 | 168451 | 9 | 2 | 48 | |
| GSE47630 | THAP5 | 168451 | 7 | 4 | 29 | |
| GSE54993 | THAP5 | 168451 | 2 | 9 | 59 | |
| GSE54994 | THAP5 | 168451 | 16 | 3 | 34 | |
| GSE60625 | THAP5 | 168451 | 0 | 0 | 11 | |
| GSE74703 | THAP5 | 168451 | 7 | 1 | 28 | |
| GSE74704 | THAP5 | 168451 | 7 | 0 | 13 | |
| TCGA | THAP5 | 168451 | 48 | 10 | 38 |
Total number of gains: 125; Total number of losses: 30; Total Number of normals: 333.
Somatic mutations of THAP5:
Generating mutation plots.
Highly correlated genes for THAP5:
Showing top 20/775 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THAP5 | TAOK1 | 0.838881 | 3 | 0 | 3 |
| THAP5 | EZH2 | 0.822069 | 3 | 0 | 3 |
| THAP5 | GRB2 | 0.821751 | 3 | 0 | 3 |
| THAP5 | RFNG | 0.81879 | 3 | 0 | 3 |
| THAP5 | U2AF1 | 0.796634 | 3 | 0 | 3 |
| THAP5 | SESTD1 | 0.788424 | 3 | 0 | 3 |
| THAP5 | JMY | 0.785233 | 3 | 0 | 3 |
| THAP5 | UBE3C | 0.783577 | 3 | 0 | 3 |
| THAP5 | PTPN4 | 0.78221 | 3 | 0 | 3 |
| THAP5 | GNS | 0.779659 | 3 | 0 | 3 |
| THAP5 | INPP4A | 0.7794 | 3 | 0 | 3 |
| THAP5 | ECSIT | 0.776727 | 3 | 0 | 3 |
| THAP5 | LRRC34 | 0.773913 | 3 | 0 | 3 |
| THAP5 | STAT2 | 0.771869 | 3 | 0 | 3 |
| THAP5 | ZNF322 | 0.770611 | 4 | 0 | 4 |
| THAP5 | CRKL | 0.767802 | 3 | 0 | 3 |
| THAP5 | SLC44A1 | 0.762485 | 3 | 0 | 3 |
| THAP5 | DGKH | 0.761469 | 3 | 0 | 3 |
| THAP5 | ANKRD40 | 0.760859 | 3 | 0 | 3 |
| THAP5 | LARP4 | 0.756623 | 3 | 0 | 3 |
For details and further investigation, click here
