| Full name: TATA-box binding protein associated factor 6 | Alias Symbol: TAFII70|TAFII80|MGC:8964|TAFII85 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 6878 | HGNC ID: HGNC:11540 | Ensembl Gene: ENSG00000106290 | OMIM ID: 602955 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF6 | 6878 | 203572_s_at | 0.4527 | 0.2543 | |
| GSE20347 | TAF6 | 6878 | 203572_s_at | 0.8217 | 0.0001 | |
| GSE23400 | TAF6 | 6878 | 203572_s_at | 0.2983 | 0.0000 | |
| GSE26886 | TAF6 | 6878 | 203572_s_at | 0.5506 | 0.0007 | |
| GSE29001 | TAF6 | 6878 | 203572_s_at | 0.4244 | 0.1516 | |
| GSE38129 | TAF6 | 6878 | 203572_s_at | 0.6069 | 0.0000 | |
| GSE45670 | TAF6 | 6878 | 203572_s_at | 0.3494 | 0.0061 | |
| GSE53622 | TAF6 | 6878 | 101548 | 0.6175 | 0.0000 | |
| GSE53624 | TAF6 | 6878 | 101548 | 0.9429 | 0.0000 | |
| GSE63941 | TAF6 | 6878 | 203572_s_at | 0.6736 | 0.0697 | |
| GSE77861 | TAF6 | 6878 | 203572_s_at | 0.5888 | 0.0057 | |
| GSE97050 | TAF6 | 6878 | A_23_P122876 | -0.0792 | 0.8657 | |
| SRP007169 | TAF6 | 6878 | RNAseq | 0.7790 | 0.1426 | |
| SRP008496 | TAF6 | 6878 | RNAseq | 0.5521 | 0.1442 | |
| SRP064894 | TAF6 | 6878 | RNAseq | 0.7978 | 0.0000 | |
| SRP133303 | TAF6 | 6878 | RNAseq | 0.7862 | 0.0000 | |
| SRP159526 | TAF6 | 6878 | RNAseq | 0.5147 | 0.0407 | |
| SRP193095 | TAF6 | 6878 | RNAseq | 0.9802 | 0.0000 | |
| SRP219564 | TAF6 | 6878 | RNAseq | 0.4739 | 0.1930 | |
| TCGA | TAF6 | 6878 | RNAseq | 0.2061 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF6 | 6878 | 13 | 0 | 17 | |
| GSE20123 | TAF6 | 6878 | 13 | 0 | 17 | |
| GSE43470 | TAF6 | 6878 | 6 | 2 | 35 | |
| GSE46452 | TAF6 | 6878 | 11 | 1 | 47 | |
| GSE47630 | TAF6 | 6878 | 7 | 3 | 30 | |
| GSE54993 | TAF6 | 6878 | 1 | 9 | 60 | |
| GSE54994 | TAF6 | 6878 | 15 | 3 | 35 | |
| GSE60625 | TAF6 | 6878 | 0 | 0 | 11 | |
| GSE74703 | TAF6 | 6878 | 6 | 1 | 29 | |
| GSE74704 | TAF6 | 6878 | 9 | 0 | 11 | |
| TCGA | TAF6 | 6878 | 52 | 6 | 38 |
Total number of gains: 133; Total number of losses: 25; Total Number of normals: 330.
Somatic mutations of TAF6:
Generating mutation plots.
Highly correlated genes for TAF6:
Showing top 20/1751 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF6 | IRF2BP2 | 0.810912 | 3 | 0 | 3 |
| TAF6 | RPS19BP1 | 0.808653 | 3 | 0 | 3 |
| TAF6 | PTCD1 | 0.80767 | 3 | 0 | 3 |
| TAF6 | SWT1 | 0.784869 | 3 | 0 | 3 |
| TAF6 | IDS | 0.776783 | 3 | 0 | 3 |
| TAF6 | ARMC10 | 0.776508 | 6 | 0 | 6 |
| TAF6 | CENPBD1 | 0.759851 | 3 | 0 | 3 |
| TAF6 | SYTL2 | 0.757787 | 3 | 0 | 3 |
| TAF6 | MEPCE | 0.751319 | 11 | 0 | 11 |
| TAF6 | PPP1R35 | 0.738241 | 8 | 0 | 8 |
| TAF6 | MAST1 | 0.736005 | 3 | 0 | 3 |
| TAF6 | RILPL1 | 0.732432 | 3 | 0 | 3 |
| TAF6 | SCNM1 | 0.73084 | 3 | 0 | 3 |
| TAF6 | WIZ | 0.724325 | 8 | 0 | 8 |
| TAF6 | PACS1 | 0.718108 | 5 | 0 | 4 |
| TAF6 | FADS1 | 0.71695 | 3 | 0 | 3 |
| TAF6 | FAM200A | 0.716907 | 4 | 0 | 4 |
| TAF6 | BRI3 | 0.716239 | 6 | 0 | 6 |
| TAF6 | NF1 | 0.716158 | 3 | 0 | 3 |
| TAF6 | FAM53B | 0.716083 | 3 | 0 | 3 |
For details and further investigation, click here
