| Full name: ankyrin repeat domain 27 | Alias Symbol: FLJ00040|DKFZp434L0718|VARP | ||
| Type: protein-coding gene | Cytoband: 19q13.11 | ||
| Entrez ID: 84079 | HGNC ID: HGNC:25310 | Ensembl Gene: ENSG00000105186 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD27 | 84079 | 221522_at | 0.3399 | 0.4057 | |
| GSE20347 | ANKRD27 | 84079 | 221522_at | 0.3440 | 0.1363 | |
| GSE23400 | ANKRD27 | 84079 | 221522_at | 0.2951 | 0.0005 | |
| GSE26886 | ANKRD27 | 84079 | 221522_at | -0.2465 | 0.1195 | |
| GSE29001 | ANKRD27 | 84079 | 221522_at | 0.4533 | 0.0510 | |
| GSE38129 | ANKRD27 | 84079 | 221522_at | 0.2421 | 0.1514 | |
| GSE45670 | ANKRD27 | 84079 | 221522_at | -0.0216 | 0.9273 | |
| GSE53622 | ANKRD27 | 84079 | 66958 | -0.1537 | 0.0387 | |
| GSE53624 | ANKRD27 | 84079 | 22558 | 0.0460 | 0.4606 | |
| GSE63941 | ANKRD27 | 84079 | 221522_at | 0.7055 | 0.0809 | |
| GSE77861 | ANKRD27 | 84079 | 221522_at | 0.3071 | 0.3058 | |
| GSE97050 | ANKRD27 | 84079 | A_33_P3280192 | -0.1787 | 0.7707 | |
| SRP007169 | ANKRD27 | 84079 | RNAseq | -0.1630 | 0.6440 | |
| SRP008496 | ANKRD27 | 84079 | RNAseq | -0.2113 | 0.3524 | |
| SRP064894 | ANKRD27 | 84079 | RNAseq | 0.0377 | 0.8720 | |
| SRP133303 | ANKRD27 | 84079 | RNAseq | 0.0631 | 0.8337 | |
| SRP159526 | ANKRD27 | 84079 | RNAseq | -0.1062 | 0.7158 | |
| SRP193095 | ANKRD27 | 84079 | RNAseq | -0.0093 | 0.9186 | |
| SRP219564 | ANKRD27 | 84079 | RNAseq | -0.3630 | 0.0423 | |
| TCGA | ANKRD27 | 84079 | RNAseq | 0.0119 | 0.8097 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKRD27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD27 | 84079 | 7 | 6 | 17 | |
| GSE20123 | ANKRD27 | 84079 | 7 | 5 | 18 | |
| GSE43470 | ANKRD27 | 84079 | 5 | 6 | 32 | |
| GSE46452 | ANKRD27 | 84079 | 47 | 1 | 11 | |
| GSE47630 | ANKRD27 | 84079 | 8 | 6 | 26 | |
| GSE54993 | ANKRD27 | 84079 | 17 | 3 | 50 | |
| GSE54994 | ANKRD27 | 84079 | 7 | 9 | 37 | |
| GSE60625 | ANKRD27 | 84079 | 9 | 0 | 2 | |
| GSE74703 | ANKRD27 | 84079 | 5 | 4 | 27 | |
| GSE74704 | ANKRD27 | 84079 | 6 | 3 | 11 | |
| TCGA | ANKRD27 | 84079 | 19 | 11 | 66 |
Total number of gains: 137; Total number of losses: 54; Total Number of normals: 297.
Somatic mutations of ANKRD27:
Generating mutation plots.
Highly correlated genes for ANKRD27:
Showing top 20/315 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD27 | SPATA2 | 0.798144 | 3 | 0 | 3 |
| ANKRD27 | NVL | 0.789721 | 3 | 0 | 3 |
| ANKRD27 | SSBP4 | 0.788182 | 3 | 0 | 3 |
| ANKRD27 | TAF15 | 0.768132 | 3 | 0 | 3 |
| ANKRD27 | DFFA | 0.74191 | 3 | 0 | 3 |
| ANKRD27 | DNAJC19 | 0.733194 | 3 | 0 | 3 |
| ANKRD27 | MRPS6 | 0.732854 | 3 | 0 | 3 |
| ANKRD27 | SPSB1 | 0.727887 | 3 | 0 | 3 |
| ANKRD27 | FOXK2 | 0.72677 | 3 | 0 | 3 |
| ANKRD27 | PRDM15 | 0.726518 | 3 | 0 | 3 |
| ANKRD27 | ARHGAP39 | 0.726339 | 3 | 0 | 3 |
| ANKRD27 | KRTCAP2 | 0.725629 | 3 | 0 | 3 |
| ANKRD27 | TMTC4 | 0.713759 | 3 | 0 | 3 |
| ANKRD27 | GPATCH1 | 0.713291 | 10 | 0 | 10 |
| ANKRD27 | BCL9L | 0.712522 | 3 | 0 | 3 |
| ANKRD27 | ZNF496 | 0.71237 | 3 | 0 | 3 |
| ANKRD27 | TRIM47 | 0.70996 | 3 | 0 | 3 |
| ANKRD27 | SLC45A4 | 0.707303 | 3 | 0 | 3 |
| ANKRD27 | DIDO1 | 0.706632 | 3 | 0 | 3 |
| ANKRD27 | KLHDC3 | 0.706252 | 3 | 0 | 3 |
For details and further investigation, click here
