| Full name: NIMA related kinase 9 | Alias Symbol: Nek8|NERCC|DKFZp434D0935|MGC16714 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 91754 | HGNC ID: HGNC:18591 | Ensembl Gene: ENSG00000119638 | OMIM ID: 609798 |
| Drug and gene relationship at DGIdb | |||
Expression of NEK9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEK9 | 91754 | 212299_at | -0.3201 | 0.6044 | |
| GSE20347 | NEK9 | 91754 | 212299_at | 0.4062 | 0.0012 | |
| GSE23400 | NEK9 | 91754 | 212299_at | 0.2564 | 0.0009 | |
| GSE26886 | NEK9 | 91754 | 212299_at | -0.3219 | 0.2497 | |
| GSE29001 | NEK9 | 91754 | 212299_at | 0.4721 | 0.1688 | |
| GSE38129 | NEK9 | 91754 | 212299_at | -0.0290 | 0.8534 | |
| GSE45670 | NEK9 | 91754 | 212299_at | -0.0061 | 0.9703 | |
| GSE53622 | NEK9 | 91754 | 9491 | 0.0109 | 0.9199 | |
| GSE53624 | NEK9 | 91754 | 9491 | 0.1212 | 0.1656 | |
| GSE63941 | NEK9 | 91754 | 212299_at | -0.1925 | 0.6526 | |
| GSE77861 | NEK9 | 91754 | 212299_at | 0.2903 | 0.2584 | |
| GSE97050 | NEK9 | 91754 | A_24_P347480 | -0.4168 | 0.2465 | |
| SRP007169 | NEK9 | 91754 | RNAseq | 0.6372 | 0.1009 | |
| SRP008496 | NEK9 | 91754 | RNAseq | 0.7748 | 0.0046 | |
| SRP064894 | NEK9 | 91754 | RNAseq | 0.1092 | 0.4461 | |
| SRP133303 | NEK9 | 91754 | RNAseq | 0.0285 | 0.8695 | |
| SRP159526 | NEK9 | 91754 | RNAseq | 0.1446 | 0.5342 | |
| SRP193095 | NEK9 | 91754 | RNAseq | 0.1186 | 0.1439 | |
| SRP219564 | NEK9 | 91754 | RNAseq | -0.1451 | 0.6799 | |
| TCGA | NEK9 | 91754 | RNAseq | -0.0820 | 0.0845 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NEK9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEK9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEK9 | 91754 | 8 | 3 | 19 | |
| GSE20123 | NEK9 | 91754 | 8 | 3 | 19 | |
| GSE43470 | NEK9 | 91754 | 8 | 3 | 32 | |
| GSE46452 | NEK9 | 91754 | 16 | 3 | 40 | |
| GSE47630 | NEK9 | 91754 | 11 | 8 | 21 | |
| GSE54993 | NEK9 | 91754 | 3 | 8 | 59 | |
| GSE54994 | NEK9 | 91754 | 19 | 4 | 30 | |
| GSE60625 | NEK9 | 91754 | 0 | 2 | 9 | |
| GSE74703 | NEK9 | 91754 | 7 | 3 | 26 | |
| GSE74704 | NEK9 | 91754 | 3 | 3 | 14 | |
| TCGA | NEK9 | 91754 | 33 | 16 | 47 |
Total number of gains: 116; Total number of losses: 56; Total Number of normals: 316.
Somatic mutations of NEK9:
Generating mutation plots.
Highly correlated genes for NEK9:
Showing top 20/377 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEK9 | ETS2 | 0.796683 | 3 | 0 | 3 |
| NEK9 | TCF7L1 | 0.775399 | 5 | 0 | 4 |
| NEK9 | COL28A1 | 0.759636 | 3 | 0 | 3 |
| NEK9 | HMCN1 | 0.753073 | 3 | 0 | 3 |
| NEK9 | SMS | 0.746345 | 3 | 0 | 3 |
| NEK9 | SLC39A1 | 0.7414 | 3 | 0 | 3 |
| NEK9 | LMNA | 0.74005 | 3 | 0 | 3 |
| NEK9 | EP400 | 0.736462 | 3 | 0 | 3 |
| NEK9 | ARRB1 | 0.730924 | 3 | 0 | 3 |
| NEK9 | MTMR9 | 0.729632 | 3 | 0 | 3 |
| NEK9 | ZSWIM5 | 0.722499 | 3 | 0 | 3 |
| NEK9 | PDK3 | 0.720175 | 3 | 0 | 3 |
| NEK9 | MRPL40 | 0.718686 | 3 | 0 | 3 |
| NEK9 | TMED8 | 0.711215 | 4 | 0 | 4 |
| NEK9 | NCL | 0.708768 | 3 | 0 | 3 |
| NEK9 | HSPA2 | 0.707069 | 4 | 0 | 3 |
| NEK9 | TSPAN2 | 0.703241 | 4 | 0 | 4 |
| NEK9 | PREX2 | 0.701969 | 3 | 0 | 3 |
| NEK9 | KCND3 | 0.701845 | 3 | 0 | 3 |
| NEK9 | MRPL10 | 0.70133 | 3 | 0 | 3 |
For details and further investigation, click here
