| Full name: TATA-box binding protein associated factor 7 | Alias Symbol: TAFII55 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 6879 | HGNC ID: HGNC:11541 | Ensembl Gene: ENSG00000178913 | OMIM ID: 600573 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF7 | 6879 | 201023_at | -0.4408 | 0.3471 | |
| GSE20347 | TAF7 | 6879 | 201023_at | 0.2749 | 0.1254 | |
| GSE23400 | TAF7 | 6879 | 201023_at | 0.0498 | 0.4574 | |
| GSE26886 | TAF7 | 6879 | 201023_at | 0.1607 | 0.3599 | |
| GSE29001 | TAF7 | 6879 | 201023_at | -0.0902 | 0.8276 | |
| GSE38129 | TAF7 | 6879 | 201023_at | 0.1913 | 0.1680 | |
| GSE45670 | TAF7 | 6879 | 201023_at | -0.1265 | 0.3930 | |
| GSE63941 | TAF7 | 6879 | 201023_at | -0.0700 | 0.8959 | |
| GSE77861 | TAF7 | 6879 | 201023_at | -0.0608 | 0.8232 | |
| GSE97050 | TAF7 | 6879 | A_23_P81248 | -0.3936 | 0.1726 | |
| SRP007169 | TAF7 | 6879 | RNAseq | -0.9570 | 0.0017 | |
| SRP008496 | TAF7 | 6879 | RNAseq | -0.8373 | 0.0001 | |
| SRP064894 | TAF7 | 6879 | RNAseq | -0.2177 | 0.0865 | |
| SRP133303 | TAF7 | 6879 | RNAseq | 0.0855 | 0.7221 | |
| SRP159526 | TAF7 | 6879 | RNAseq | -0.0691 | 0.8462 | |
| SRP193095 | TAF7 | 6879 | RNAseq | -0.2008 | 0.0588 | |
| SRP219564 | TAF7 | 6879 | RNAseq | -0.1549 | 0.4531 | |
| TCGA | TAF7 | 6879 | RNAseq | 0.0189 | 0.6714 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAF7 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TAF7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF7 | 6879 | 2 | 11 | 17 | |
| GSE20123 | TAF7 | 6879 | 3 | 11 | 16 | |
| GSE43470 | TAF7 | 6879 | 2 | 10 | 31 | |
| GSE46452 | TAF7 | 6879 | 0 | 27 | 32 | |
| GSE47630 | TAF7 | 6879 | 1 | 19 | 20 | |
| GSE54993 | TAF7 | 6879 | 9 | 1 | 60 | |
| GSE54994 | TAF7 | 6879 | 2 | 14 | 37 | |
| GSE60625 | TAF7 | 6879 | 0 | 0 | 11 | |
| GSE74703 | TAF7 | 6879 | 2 | 7 | 27 | |
| GSE74704 | TAF7 | 6879 | 2 | 5 | 13 | |
| TCGA | TAF7 | 6879 | 3 | 38 | 55 |
Total number of gains: 26; Total number of losses: 143; Total Number of normals: 319.
Somatic mutations of TAF7:
Generating mutation plots.
Highly correlated genes for TAF7:
Showing top 20/299 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF7 | BTBD7 | 0.830488 | 3 | 0 | 3 |
| TAF7 | SCAMP1 | 0.774639 | 4 | 0 | 4 |
| TAF7 | NDUFS1 | 0.773737 | 3 | 0 | 3 |
| TAF7 | ING2 | 0.773157 | 4 | 0 | 4 |
| TAF7 | GIN1 | 0.770241 | 4 | 0 | 4 |
| TAF7 | MCCC1 | 0.762888 | 3 | 0 | 3 |
| TAF7 | RAB11FIP2 | 0.757798 | 3 | 0 | 3 |
| TAF7 | RBM8A | 0.754506 | 3 | 0 | 3 |
| TAF7 | ZNF627 | 0.74088 | 3 | 0 | 3 |
| TAF7 | COX7B | 0.739098 | 4 | 0 | 4 |
| TAF7 | SETMAR | 0.735935 | 3 | 0 | 3 |
| TAF7 | PRKAR1A | 0.723904 | 3 | 0 | 3 |
| TAF7 | RCOR3 | 0.71977 | 3 | 0 | 3 |
| TAF7 | DNAAF2 | 0.718082 | 3 | 0 | 3 |
| TAF7 | SETD3 | 0.717711 | 3 | 0 | 3 |
| TAF7 | MED4 | 0.716145 | 4 | 0 | 4 |
| TAF7 | ANG | 0.715069 | 4 | 0 | 3 |
| TAF7 | CLDND1 | 0.710806 | 4 | 0 | 4 |
| TAF7 | LARP7 | 0.710711 | 4 | 0 | 3 |
| TAF7 | PPM1A | 0.709479 | 4 | 0 | 3 |
For details and further investigation, click here
