| Full name: RNA binding motif protein 8A | Alias Symbol: ZNRP|BOV-1A|BOV-1B|BOV-1C|RBM8B|Y14 | ||
| Type: protein-coding gene | Cytoband: 1q21.1 | ||
| Entrez ID: 9939 | HGNC ID: HGNC:9905 | Ensembl Gene: ENSG00000265241 | OMIM ID: 605313 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RBM8A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM8A | 9939 | 222443_s_at | 0.1292 | 0.6519 | |
| GSE20347 | RBM8A | 9939 | 214113_s_at | -0.5426 | 0.0004 | |
| GSE23400 | RBM8A | 9939 | 214113_s_at | -0.3022 | 0.0018 | |
| GSE26886 | RBM8A | 9939 | 214113_s_at | -0.6977 | 0.0006 | |
| GSE29001 | RBM8A | 9939 | 214113_s_at | -0.4559 | 0.1761 | |
| GSE38129 | RBM8A | 9939 | 214113_s_at | -0.0862 | 0.6562 | |
| GSE45670 | RBM8A | 9939 | 222443_s_at | -0.0923 | 0.4907 | |
| GSE53622 | RBM8A | 9939 | 949 | -0.1730 | 0.0162 | |
| GSE53624 | RBM8A | 9939 | 949 | -0.1248 | 0.0302 | |
| GSE63941 | RBM8A | 9939 | 214113_s_at | 1.3424 | 0.0067 | |
| GSE77861 | RBM8A | 9939 | 222443_s_at | -0.2556 | 0.4287 | |
| GSE97050 | RBM8A | 9939 | A_23_P104116 | -0.2532 | 0.4918 | |
| SRP007169 | RBM8A | 9939 | RNAseq | -0.8711 | 0.0061 | |
| SRP008496 | RBM8A | 9939 | RNAseq | -0.5269 | 0.0094 | |
| SRP064894 | RBM8A | 9939 | RNAseq | -0.5477 | 0.0055 | |
| SRP133303 | RBM8A | 9939 | RNAseq | -0.1693 | 0.1751 | |
| SRP159526 | RBM8A | 9939 | RNAseq | -0.0331 | 0.7968 | |
| SRP193095 | RBM8A | 9939 | RNAseq | -0.3693 | 0.0028 | |
| SRP219564 | RBM8A | 9939 | RNAseq | -0.2604 | 0.5629 | |
| TCGA | RBM8A | 9939 | RNAseq | 0.0829 | 0.0743 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RBM8A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM8A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM8A | 9939 | 13 | 0 | 17 | |
| GSE20123 | RBM8A | 9939 | 13 | 0 | 17 | |
| GSE43470 | RBM8A | 9939 | 5 | 2 | 36 | |
| GSE46452 | RBM8A | 9939 | 2 | 1 | 56 | |
| GSE47630 | RBM8A | 9939 | 12 | 2 | 26 | |
| GSE54993 | RBM8A | 9939 | 0 | 2 | 68 | |
| GSE54994 | RBM8A | 9939 | 15 | 0 | 38 | |
| GSE60625 | RBM8A | 9939 | 0 | 0 | 11 | |
| GSE74703 | RBM8A | 9939 | 5 | 2 | 29 | |
| GSE74704 | RBM8A | 9939 | 6 | 0 | 14 | |
| TCGA | RBM8A | 9939 | 33 | 15 | 48 |
Total number of gains: 104; Total number of losses: 24; Total Number of normals: 360.
Somatic mutations of RBM8A:
Generating mutation plots.
Highly correlated genes for RBM8A:
Showing top 20/735 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM8A | ZNF564 | 0.803844 | 3 | 0 | 3 |
| RBM8A | KLHDC2 | 0.788834 | 3 | 0 | 3 |
| RBM8A | METTL14 | 0.786351 | 3 | 0 | 3 |
| RBM8A | NAA30 | 0.772079 | 3 | 0 | 3 |
| RBM8A | DUSP16 | 0.771766 | 3 | 0 | 3 |
| RBM8A | ZNF740 | 0.769206 | 3 | 0 | 3 |
| RBM8A | PEX2 | 0.764274 | 3 | 0 | 3 |
| RBM8A | ZNF227 | 0.763201 | 3 | 0 | 3 |
| RBM8A | COMMD5 | 0.761889 | 3 | 0 | 3 |
| RBM8A | NAA15 | 0.758159 | 3 | 0 | 3 |
| RBM8A | TAF7 | 0.754506 | 3 | 0 | 3 |
| RBM8A | ZFAND1 | 0.754164 | 3 | 0 | 3 |
| RBM8A | TYW5 | 0.754047 | 3 | 0 | 3 |
| RBM8A | RLIM | 0.749262 | 3 | 0 | 3 |
| RBM8A | AARS2 | 0.735965 | 3 | 0 | 3 |
| RBM8A | MRPL30 | 0.735178 | 3 | 0 | 3 |
| RBM8A | ZNF654 | 0.733357 | 5 | 0 | 5 |
| RBM8A | MRFAP1 | 0.732052 | 3 | 0 | 3 |
| RBM8A | BLOC1S2 | 0.726889 | 4 | 0 | 4 |
| RBM8A | SNRNP200 | 0.718907 | 3 | 0 | 3 |
For details and further investigation, click here
