| Full name: tudor and KH domain containing | Alias Symbol: TDRD2 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 11022 | HGNC ID: HGNC:11713 | Ensembl Gene: ENSG00000182134 | OMIM ID: 609501 |
| Drug and gene relationship at DGIdb | |||
Expression of TDRKH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TDRKH | 11022 | 223530_at | 0.9100 | 0.0793 | |
| GSE20347 | TDRKH | 11022 | 221053_s_at | -0.0109 | 0.9075 | |
| GSE23400 | TDRKH | 11022 | 221053_s_at | -0.2629 | 0.0000 | |
| GSE26886 | TDRKH | 11022 | 223530_at | 1.1245 | 0.0003 | |
| GSE29001 | TDRKH | 11022 | 221052_at | 0.0652 | 0.8440 | |
| GSE38129 | TDRKH | 11022 | 221053_s_at | -0.0388 | 0.6608 | |
| GSE45670 | TDRKH | 11022 | 223530_at | 0.7012 | 0.0395 | |
| GSE53622 | TDRKH | 11022 | 117221 | 0.5957 | 0.0004 | |
| GSE53624 | TDRKH | 11022 | 117221 | 0.8186 | 0.0000 | |
| GSE63941 | TDRKH | 11022 | 223530_at | 2.8851 | 0.0025 | |
| GSE77861 | TDRKH | 11022 | 223530_at | 0.1072 | 0.5539 | |
| GSE97050 | TDRKH | 11022 | A_23_P46351 | 0.0337 | 0.9409 | |
| SRP064894 | TDRKH | 11022 | RNAseq | 0.7126 | 0.0019 | |
| SRP133303 | TDRKH | 11022 | RNAseq | 0.4753 | 0.1113 | |
| SRP159526 | TDRKH | 11022 | RNAseq | 1.2731 | 0.0011 | |
| SRP193095 | TDRKH | 11022 | RNAseq | 0.5227 | 0.0081 | |
| SRP219564 | TDRKH | 11022 | RNAseq | 0.8624 | 0.1497 | |
| TCGA | TDRKH | 11022 | RNAseq | 0.0643 | 0.6699 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by TDRKH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TDRKH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TDRKH | 11022 | 15 | 0 | 15 | |
| GSE20123 | TDRKH | 11022 | 15 | 0 | 15 | |
| GSE43470 | TDRKH | 11022 | 8 | 2 | 33 | |
| GSE46452 | TDRKH | 11022 | 2 | 1 | 56 | |
| GSE47630 | TDRKH | 11022 | 15 | 0 | 25 | |
| GSE54993 | TDRKH | 11022 | 0 | 4 | 66 | |
| GSE54994 | TDRKH | 11022 | 15 | 0 | 38 | |
| GSE60625 | TDRKH | 11022 | 0 | 0 | 11 | |
| GSE74703 | TDRKH | 11022 | 7 | 1 | 28 | |
| GSE74704 | TDRKH | 11022 | 7 | 0 | 13 | |
| TCGA | TDRKH | 11022 | 38 | 2 | 56 |
Total number of gains: 122; Total number of losses: 10; Total Number of normals: 356.
Somatic mutations of TDRKH:
Generating mutation plots.
Highly correlated genes for TDRKH:
Showing top 20/520 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TDRKH | PITX2 | 0.781786 | 3 | 0 | 3 |
| TDRKH | NPHP4 | 0.763518 | 3 | 0 | 3 |
| TDRKH | COMMD7 | 0.718178 | 4 | 0 | 3 |
| TDRKH | DNAJC11 | 0.710778 | 3 | 0 | 3 |
| TDRKH | SFMBT1 | 0.694799 | 3 | 0 | 3 |
| TDRKH | MMP15 | 0.690457 | 3 | 0 | 3 |
| TDRKH | ZFP1 | 0.687062 | 3 | 0 | 3 |
| TDRKH | EVI5L | 0.686613 | 3 | 0 | 3 |
| TDRKH | ZNF8 | 0.685874 | 3 | 0 | 3 |
| TDRKH | FOXO6 | 0.685503 | 3 | 0 | 3 |
| TDRKH | ACACA | 0.681731 | 4 | 0 | 3 |
| TDRKH | ZSWIM5 | 0.680919 | 3 | 0 | 3 |
| TDRKH | C12orf65 | 0.67782 | 6 | 0 | 5 |
| TDRKH | SOGA1 | 0.673912 | 4 | 0 | 3 |
| TDRKH | C15orf61 | 0.673808 | 3 | 0 | 3 |
| TDRKH | LRRC14 | 0.670331 | 3 | 0 | 3 |
| TDRKH | PET117 | 0.668046 | 3 | 0 | 3 |
| TDRKH | USP28 | 0.667299 | 5 | 0 | 4 |
| TDRKH | CDH18 | 0.664138 | 3 | 0 | 3 |
| TDRKH | ATAD3A | 0.662331 | 3 | 0 | 3 |
For details and further investigation, click here
