| Full name: Scm like with four mbt domains 1 | Alias Symbol: RU1|DKFZp434L243|SFMBT | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 51460 | HGNC ID: HGNC:20255 | Ensembl Gene: ENSG00000163935 | OMIM ID: 607319 |
| Drug and gene relationship at DGIdb | |||
Expression of SFMBT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFMBT1 | 51460 | 213370_s_at | 0.2826 | 0.3994 | |
| GSE20347 | SFMBT1 | 51460 | 213370_s_at | -0.0042 | 0.9742 | |
| GSE23400 | SFMBT1 | 51460 | 213370_s_at | -0.0170 | 0.7955 | |
| GSE26886 | SFMBT1 | 51460 | 213370_s_at | -0.2101 | 0.1656 | |
| GSE29001 | SFMBT1 | 51460 | 213370_s_at | 0.1636 | 0.5183 | |
| GSE38129 | SFMBT1 | 51460 | 213370_s_at | 0.1096 | 0.2608 | |
| GSE45670 | SFMBT1 | 51460 | 213370_s_at | -0.1167 | 0.4125 | |
| GSE63941 | SFMBT1 | 51460 | 213370_s_at | 1.1136 | 0.0044 | |
| GSE77861 | SFMBT1 | 51460 | 213370_s_at | -0.1754 | 0.1945 | |
| GSE97050 | SFMBT1 | 51460 | A_23_P259393 | 0.0231 | 0.9224 | |
| SRP007169 | SFMBT1 | 51460 | RNAseq | 0.3261 | 0.4964 | |
| SRP008496 | SFMBT1 | 51460 | RNAseq | 0.2920 | 0.3775 | |
| SRP064894 | SFMBT1 | 51460 | RNAseq | -0.2900 | 0.0897 | |
| SRP133303 | SFMBT1 | 51460 | RNAseq | -0.3891 | 0.0193 | |
| SRP159526 | SFMBT1 | 51460 | RNAseq | -0.3842 | 0.0389 | |
| SRP193095 | SFMBT1 | 51460 | RNAseq | -0.2585 | 0.0920 | |
| SRP219564 | SFMBT1 | 51460 | RNAseq | -0.6085 | 0.0018 | |
| TCGA | SFMBT1 | 51460 | RNAseq | -0.3002 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SFMBT1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SFMBT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFMBT1 | 51460 | 0 | 18 | 12 | |
| GSE20123 | SFMBT1 | 51460 | 0 | 19 | 11 | |
| GSE43470 | SFMBT1 | 51460 | 0 | 18 | 25 | |
| GSE46452 | SFMBT1 | 51460 | 2 | 17 | 40 | |
| GSE47630 | SFMBT1 | 51460 | 1 | 24 | 15 | |
| GSE54993 | SFMBT1 | 51460 | 6 | 2 | 62 | |
| GSE54994 | SFMBT1 | 51460 | 0 | 33 | 20 | |
| GSE60625 | SFMBT1 | 51460 | 5 | 0 | 6 | |
| GSE74703 | SFMBT1 | 51460 | 0 | 14 | 22 | |
| GSE74704 | SFMBT1 | 51460 | 0 | 12 | 8 | |
| TCGA | SFMBT1 | 51460 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 235; Total Number of normals: 239.
Somatic mutations of SFMBT1:
Generating mutation plots.
Highly correlated genes for SFMBT1:
Showing top 20/178 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFMBT1 | NASP | 0.789278 | 3 | 0 | 3 |
| SFMBT1 | PPP1R37 | 0.774548 | 3 | 0 | 3 |
| SFMBT1 | PPP1R16A | 0.767557 | 3 | 0 | 3 |
| SFMBT1 | SYNE2 | 0.759732 | 3 | 0 | 3 |
| SFMBT1 | CLASRP | 0.757893 | 3 | 0 | 3 |
| SFMBT1 | USP21 | 0.752146 | 3 | 0 | 3 |
| SFMBT1 | MRPS6 | 0.749474 | 3 | 0 | 3 |
| SFMBT1 | AKAP8L | 0.745227 | 3 | 0 | 3 |
| SFMBT1 | TCEANC2 | 0.742487 | 3 | 0 | 3 |
| SFMBT1 | FOXP4 | 0.741128 | 3 | 0 | 3 |
| SFMBT1 | DICER1 | 0.730874 | 3 | 0 | 3 |
| SFMBT1 | ERH | 0.730821 | 3 | 0 | 3 |
| SFMBT1 | DNAJC11 | 0.725315 | 3 | 0 | 3 |
| SFMBT1 | CHD8 | 0.722572 | 3 | 0 | 3 |
| SFMBT1 | ZNF789 | 0.720592 | 3 | 0 | 3 |
| SFMBT1 | BRD4 | 0.718252 | 3 | 0 | 3 |
| SFMBT1 | ARHGAP39 | 0.713882 | 3 | 0 | 3 |
| SFMBT1 | NADK | 0.713363 | 3 | 0 | 3 |
| SFMBT1 | USP36 | 0.712787 | 3 | 0 | 3 |
| SFMBT1 | SNW1 | 0.709312 | 3 | 0 | 3 |
For details and further investigation, click here
