| Full name: chromosome 12 open reading frame 65 | Alias Symbol: FLJ38663|SPG55 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 91574 | HGNC ID: HGNC:26784 | Ensembl Gene: ENSG00000130921 | OMIM ID: 613541 |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf65:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf65 | 91574 | 223476_s_at | 0.2200 | 0.3805 | |
| GSE26886 | C12orf65 | 91574 | 223477_s_at | 0.7830 | 0.0000 | |
| GSE45670 | C12orf65 | 91574 | 223477_s_at | 0.1389 | 0.2074 | |
| GSE53622 | C12orf65 | 91574 | 45717 | 0.5703 | 0.0000 | |
| GSE53624 | C12orf65 | 91574 | 45717 | 0.7600 | 0.0000 | |
| GSE63941 | C12orf65 | 91574 | 223477_s_at | 0.2987 | 0.5189 | |
| GSE77861 | C12orf65 | 91574 | 223477_s_at | 0.1284 | 0.5079 | |
| GSE97050 | C12orf65 | 91574 | A_32_P11894 | 0.1432 | 0.6076 | |
| SRP007169 | C12orf65 | 91574 | RNAseq | 1.6767 | 0.0036 | |
| SRP008496 | C12orf65 | 91574 | RNAseq | 1.4912 | 0.0014 | |
| SRP064894 | C12orf65 | 91574 | RNAseq | 0.5534 | 0.0030 | |
| SRP133303 | C12orf65 | 91574 | RNAseq | 0.2994 | 0.1128 | |
| SRP159526 | C12orf65 | 91574 | RNAseq | 0.8237 | 0.0145 | |
| SRP193095 | C12orf65 | 91574 | RNAseq | 0.2177 | 0.0070 | |
| SRP219564 | C12orf65 | 91574 | RNAseq | 0.2018 | 0.3908 | |
| TCGA | C12orf65 | 91574 | RNAseq | 0.0770 | 0.2661 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by C12orf65 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf65:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf65 | 91574 | 5 | 5 | 20 | |
| GSE20123 | C12orf65 | 91574 | 5 | 5 | 20 | |
| GSE43470 | C12orf65 | 91574 | 2 | 1 | 40 | |
| GSE46452 | C12orf65 | 91574 | 9 | 1 | 49 | |
| GSE47630 | C12orf65 | 91574 | 9 | 3 | 28 | |
| GSE54993 | C12orf65 | 91574 | 0 | 5 | 65 | |
| GSE54994 | C12orf65 | 91574 | 4 | 8 | 41 | |
| GSE60625 | C12orf65 | 91574 | 0 | 0 | 11 | |
| GSE74703 | C12orf65 | 91574 | 2 | 0 | 34 | |
| GSE74704 | C12orf65 | 91574 | 3 | 3 | 14 | |
| TCGA | C12orf65 | 91574 | 21 | 11 | 64 |
Total number of gains: 60; Total number of losses: 42; Total Number of normals: 386.
Somatic mutations of C12orf65:
Generating mutation plots.
Highly correlated genes for C12orf65:
Showing top 20/1218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf65 | SH3RF3 | 0.848656 | 3 | 0 | 3 |
| C12orf65 | TRIM47 | 0.792743 | 3 | 0 | 3 |
| C12orf65 | ROMO1 | 0.790087 | 3 | 0 | 3 |
| C12orf65 | BBS9 | 0.78684 | 3 | 0 | 3 |
| C12orf65 | UBIAD1 | 0.782662 | 3 | 0 | 3 |
| C12orf65 | MPG | 0.775799 | 3 | 0 | 3 |
| C12orf65 | POMZP3 | 0.770772 | 3 | 0 | 3 |
| C12orf65 | INO80E | 0.768177 | 3 | 0 | 3 |
| C12orf65 | CSNK2A2 | 0.767781 | 3 | 0 | 3 |
| C12orf65 | EHD1 | 0.76749 | 3 | 0 | 3 |
| C12orf65 | CHCHD2 | 0.761289 | 3 | 0 | 3 |
| C12orf65 | ACACA | 0.761192 | 3 | 0 | 3 |
| C12orf65 | PTCD1 | 0.756232 | 3 | 0 | 3 |
| C12orf65 | RRNAD1 | 0.755973 | 3 | 0 | 3 |
| C12orf65 | RICTOR | 0.752366 | 3 | 0 | 3 |
| C12orf65 | CADPS2 | 0.750961 | 3 | 0 | 3 |
| C12orf65 | MGAT4B | 0.746611 | 3 | 0 | 3 |
| C12orf65 | RPL26L1 | 0.738804 | 3 | 0 | 3 |
| C12orf65 | EBAG9 | 0.737783 | 3 | 0 | 3 |
| C12orf65 | MRPL41 | 0.732809 | 3 | 0 | 3 |
For details and further investigation, click here
