| Full name: DnaJ heat shock protein family (Hsp40) member C11 | Alias Symbol: FLJ10737 | ||
| Type: protein-coding gene | Cytoband: 1p36.31 | ||
| Entrez ID: 55735 | HGNC ID: HGNC:25570 | Ensembl Gene: ENSG00000007923 | OMIM ID: 614827 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DNAJC11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC11 | 55735 | 215792_s_at | 0.4574 | 0.1683 | |
| GSE20347 | DNAJC11 | 55735 | 215792_s_at | 0.1748 | 0.1314 | |
| GSE23400 | DNAJC11 | 55735 | 215792_s_at | 0.1685 | 0.0002 | |
| GSE26886 | DNAJC11 | 55735 | 215792_s_at | -0.1147 | 0.6304 | |
| GSE29001 | DNAJC11 | 55735 | 215792_s_at | 0.1142 | 0.4524 | |
| GSE38129 | DNAJC11 | 55735 | 215792_s_at | 0.1687 | 0.0429 | |
| GSE45670 | DNAJC11 | 55735 | 215792_s_at | 0.3258 | 0.0073 | |
| GSE53622 | DNAJC11 | 55735 | 12349 | 0.1123 | 0.0805 | |
| GSE53624 | DNAJC11 | 55735 | 12349 | 0.4142 | 0.0000 | |
| GSE63941 | DNAJC11 | 55735 | 215792_s_at | 0.7442 | 0.0168 | |
| GSE77861 | DNAJC11 | 55735 | 215792_s_at | 0.1294 | 0.2908 | |
| GSE97050 | DNAJC11 | 55735 | A_33_P3241108 | 0.2097 | 0.3789 | |
| SRP007169 | DNAJC11 | 55735 | RNAseq | 0.1102 | 0.7806 | |
| SRP008496 | DNAJC11 | 55735 | RNAseq | -0.2702 | 0.2949 | |
| SRP064894 | DNAJC11 | 55735 | RNAseq | 0.2268 | 0.2288 | |
| SRP133303 | DNAJC11 | 55735 | RNAseq | 0.3717 | 0.0065 | |
| SRP159526 | DNAJC11 | 55735 | RNAseq | 0.3283 | 0.2048 | |
| SRP193095 | DNAJC11 | 55735 | RNAseq | 0.2767 | 0.0027 | |
| SRP219564 | DNAJC11 | 55735 | RNAseq | 0.1048 | 0.7176 | |
| TCGA | DNAJC11 | 55735 | RNAseq | -0.0172 | 0.7201 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAJC11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC11 | 55735 | 3 | 6 | 21 | |
| GSE20123 | DNAJC11 | 55735 | 3 | 5 | 22 | |
| GSE43470 | DNAJC11 | 55735 | 6 | 5 | 32 | |
| GSE46452 | DNAJC11 | 55735 | 7 | 1 | 51 | |
| GSE47630 | DNAJC11 | 55735 | 8 | 4 | 28 | |
| GSE54993 | DNAJC11 | 55735 | 3 | 2 | 65 | |
| GSE54994 | DNAJC11 | 55735 | 14 | 3 | 36 | |
| GSE60625 | DNAJC11 | 55735 | 0 | 0 | 11 | |
| GSE74703 | DNAJC11 | 55735 | 5 | 3 | 28 | |
| GSE74704 | DNAJC11 | 55735 | 3 | 0 | 17 | |
| TCGA | DNAJC11 | 55735 | 12 | 22 | 62 |
Total number of gains: 64; Total number of losses: 51; Total Number of normals: 373.
Somatic mutations of DNAJC11:
Generating mutation plots.
Highly correlated genes for DNAJC11:
Showing top 20/782 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC11 | DYRK2 | 0.810726 | 3 | 0 | 3 |
| DNAJC11 | PHC2 | 0.806975 | 3 | 0 | 3 |
| DNAJC11 | TATDN2 | 0.805282 | 3 | 0 | 3 |
| DNAJC11 | BAG6 | 0.802557 | 3 | 0 | 3 |
| DNAJC11 | SPNS1 | 0.784506 | 3 | 0 | 3 |
| DNAJC11 | XXYLT1 | 0.770962 | 3 | 0 | 3 |
| DNAJC11 | DYNC2H1 | 0.769354 | 3 | 0 | 3 |
| DNAJC11 | RHOBTB2 | 0.761442 | 3 | 0 | 3 |
| DNAJC11 | TMEM11 | 0.760752 | 3 | 0 | 3 |
| DNAJC11 | NAA25 | 0.760564 | 3 | 0 | 3 |
| DNAJC11 | SLC39A10 | 0.748893 | 3 | 0 | 3 |
| DNAJC11 | PPP1R16A | 0.746287 | 4 | 0 | 4 |
| DNAJC11 | SETX | 0.740546 | 3 | 0 | 3 |
| DNAJC11 | KBTBD7 | 0.740526 | 3 | 0 | 3 |
| DNAJC11 | CHCHD6 | 0.740355 | 3 | 0 | 3 |
| DNAJC11 | FAM90A1 | 0.740307 | 3 | 0 | 3 |
| DNAJC11 | STX10 | 0.737081 | 4 | 0 | 3 |
| DNAJC11 | DEDD2 | 0.731369 | 3 | 0 | 3 |
| DNAJC11 | MRI1 | 0.727701 | 3 | 0 | 3 |
| DNAJC11 | PCID2 | 0.726714 | 4 | 0 | 4 |
For details and further investigation, click here
