| Full name: zinc finger protein 8 | Alias Symbol: HF.18|Zfp128 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 7554 | HGNC ID: HGNC:13154 | Ensembl Gene: ENSG00000278129 | OMIM ID: 194532 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF8 | 7554 | 214901_at | 0.3209 | 0.1928 | |
| GSE20347 | ZNF8 | 7554 | 214901_at | 0.0189 | 0.8581 | |
| GSE23400 | ZNF8 | 7554 | 214901_at | -0.1423 | 0.0009 | |
| GSE26886 | ZNF8 | 7554 | 214901_at | 0.5810 | 0.0246 | |
| GSE29001 | ZNF8 | 7554 | 214901_at | 0.2932 | 0.2172 | |
| GSE38129 | ZNF8 | 7554 | 214901_at | 0.0713 | 0.4180 | |
| GSE45670 | ZNF8 | 7554 | 214901_at | 0.3513 | 0.0053 | |
| GSE53622 | ZNF8 | 7554 | 6813 | 0.1253 | 0.0898 | |
| GSE53624 | ZNF8 | 7554 | 6813 | 0.5320 | 0.0000 | |
| GSE63941 | ZNF8 | 7554 | 214901_at | -0.4209 | 0.2261 | |
| GSE77861 | ZNF8 | 7554 | 214901_at | 0.0221 | 0.8384 | |
| GSE97050 | ZNF8 | 7554 | A_23_P130466 | 0.0636 | 0.7879 | |
| SRP007169 | ZNF8 | 7554 | RNAseq | -0.1507 | 0.6781 | |
| SRP008496 | ZNF8 | 7554 | RNAseq | 0.0399 | 0.8499 | |
| SRP064894 | ZNF8 | 7554 | RNAseq | 0.2527 | 0.2474 | |
| SRP133303 | ZNF8 | 7554 | RNAseq | 0.1836 | 0.2643 | |
| SRP159526 | ZNF8 | 7554 | RNAseq | 0.3675 | 0.3402 | |
| SRP193095 | ZNF8 | 7554 | RNAseq | 0.1478 | 0.1773 | |
| SRP219564 | ZNF8 | 7554 | RNAseq | 0.1764 | 0.5267 | |
| TCGA | ZNF8 | 7554 | RNAseq | -0.0796 | 0.3239 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF8 | 7554 | 2 | 5 | 23 | |
| GSE20123 | ZNF8 | 7554 | 2 | 4 | 24 | |
| GSE43470 | ZNF8 | 7554 | 3 | 9 | 31 | |
| GSE46452 | ZNF8 | 7554 | 45 | 1 | 13 | |
| GSE47630 | ZNF8 | 7554 | 8 | 6 | 26 | |
| GSE54993 | ZNF8 | 7554 | 18 | 4 | 48 | |
| GSE54994 | ZNF8 | 7554 | 5 | 12 | 36 | |
| GSE60625 | ZNF8 | 7554 | 9 | 0 | 2 | |
| GSE74703 | ZNF8 | 7554 | 3 | 6 | 27 | |
| GSE74704 | ZNF8 | 7554 | 2 | 1 | 17 | |
| TCGA | ZNF8 | 7554 | 21 | 18 | 57 |
Total number of gains: 118; Total number of losses: 66; Total Number of normals: 304.
Somatic mutations of ZNF8:
Generating mutation plots.
Highly correlated genes for ZNF8:
Showing top 20/360 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF8 | CPNE1 | 0.75381 | 3 | 0 | 3 |
| ZNF8 | GCSH | 0.744473 | 3 | 0 | 3 |
| ZNF8 | ICAM5 | 0.742129 | 3 | 0 | 3 |
| ZNF8 | GET4 | 0.741072 | 3 | 0 | 3 |
| ZNF8 | LEMD2 | 0.724973 | 3 | 0 | 3 |
| ZNF8 | SOCS4 | 0.722725 | 3 | 0 | 3 |
| ZNF8 | TFDP2 | 0.718415 | 3 | 0 | 3 |
| ZNF8 | CCDC15 | 0.711009 | 3 | 0 | 3 |
| ZNF8 | SLC38A7 | 0.708623 | 3 | 0 | 3 |
| ZNF8 | SIX5 | 0.697551 | 3 | 0 | 3 |
| ZNF8 | CALY | 0.694362 | 3 | 0 | 3 |
| ZNF8 | AVPR1A | 0.693924 | 3 | 0 | 3 |
| ZNF8 | MED1 | 0.691899 | 3 | 0 | 3 |
| ZNF8 | TDRKH | 0.685874 | 3 | 0 | 3 |
| ZNF8 | NEDD1 | 0.681366 | 4 | 0 | 3 |
| ZNF8 | ZNF710 | 0.681121 | 3 | 0 | 3 |
| ZNF8 | NAF1 | 0.680677 | 3 | 0 | 3 |
| ZNF8 | SPATA5 | 0.680477 | 4 | 0 | 3 |
| ZNF8 | USP42 | 0.678084 | 5 | 0 | 4 |
| ZNF8 | NEIL2 | 0.674927 | 3 | 0 | 3 |
For details and further investigation, click here
