| Full name: nucleoside-triphosphatase, cancer-related | Alias Symbol: MGC13186|HCR-NTPase|THEP1 | ||
| Type: protein-coding gene | Cytoband: 1q42.2 | ||
| Entrez ID: 84284 | HGNC ID: HGNC:28204 | Ensembl Gene: ENSG00000135778 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NTPCR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NTPCR | 84284 | 223272_s_at | 0.8601 | 0.0411 | |
| GSE26886 | NTPCR | 84284 | 223272_s_at | 1.1477 | 0.0000 | |
| GSE45670 | NTPCR | 84284 | 223272_s_at | 0.3729 | 0.0658 | |
| GSE53622 | NTPCR | 84284 | 114467 | 1.0483 | 0.0000 | |
| GSE53624 | NTPCR | 84284 | 114467 | 0.9589 | 0.0000 | |
| GSE63941 | NTPCR | 84284 | 223272_s_at | 0.0309 | 0.9509 | |
| GSE77861 | NTPCR | 84284 | 223272_s_at | 0.7257 | 0.0275 | |
| GSE97050 | NTPCR | 84284 | A_23_P200252 | 0.0357 | 0.9210 | |
| SRP007169 | NTPCR | 84284 | RNAseq | 0.2180 | 0.5143 | |
| SRP008496 | NTPCR | 84284 | RNAseq | 0.1977 | 0.5329 | |
| SRP064894 | NTPCR | 84284 | RNAseq | 0.3947 | 0.1310 | |
| SRP133303 | NTPCR | 84284 | RNAseq | 0.2132 | 0.2518 | |
| SRP159526 | NTPCR | 84284 | RNAseq | 0.4948 | 0.1514 | |
| SRP193095 | NTPCR | 84284 | RNAseq | 0.1371 | 0.3154 | |
| SRP219564 | NTPCR | 84284 | RNAseq | 0.4962 | 0.2671 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NTPCR expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NTPCR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NTPCR | 84284 | 12 | 0 | 18 | |
| GSE20123 | NTPCR | 84284 | 12 | 0 | 18 | |
| GSE43470 | NTPCR | 84284 | 8 | 0 | 35 | |
| GSE46452 | NTPCR | 84284 | 4 | 2 | 53 | |
| GSE47630 | NTPCR | 84284 | 15 | 0 | 25 | |
| GSE54993 | NTPCR | 84284 | 0 | 6 | 64 | |
| GSE54994 | NTPCR | 84284 | 16 | 0 | 37 | |
| GSE60625 | NTPCR | 84284 | 0 | 0 | 11 | |
| GSE74703 | NTPCR | 84284 | 8 | 0 | 28 | |
| GSE74704 | NTPCR | 84284 | 6 | 0 | 14 | |
| TCGA | NTPCR | 84284 | 44 | 3 | 49 |
Total number of gains: 125; Total number of losses: 11; Total Number of normals: 352.
Somatic mutations of NTPCR:
Generating mutation plots.
Highly correlated genes for NTPCR:
Showing top 20/1431 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NTPCR | POLRMT | 0.80921 | 3 | 0 | 3 |
| NTPCR | MARK1 | 0.806449 | 5 | 0 | 5 |
| NTPCR | IGF2R | 0.799529 | 4 | 0 | 4 |
| NTPCR | RGS19 | 0.799136 | 4 | 0 | 4 |
| NTPCR | CBL | 0.793754 | 3 | 0 | 3 |
| NTPCR | PITX2 | 0.789832 | 3 | 0 | 3 |
| NTPCR | SSBP4 | 0.783289 | 4 | 0 | 4 |
| NTPCR | FAM89B | 0.782044 | 3 | 0 | 3 |
| NTPCR | SP4 | 0.777251 | 3 | 0 | 3 |
| NTPCR | DEXI | 0.769696 | 3 | 0 | 3 |
| NTPCR | TRMT12 | 0.76724 | 4 | 0 | 4 |
| NTPCR | ZFHX3 | 0.764647 | 3 | 0 | 3 |
| NTPCR | HOXA10 | 0.76351 | 3 | 0 | 3 |
| NTPCR | ORC4 | 0.762318 | 4 | 0 | 4 |
| NTPCR | ALKBH6 | 0.761089 | 4 | 0 | 4 |
| NTPCR | UBQLN4 | 0.758578 | 4 | 0 | 4 |
| NTPCR | PIK3R3 | 0.758074 | 3 | 0 | 3 |
| NTPCR | SRXN1 | 0.750988 | 3 | 0 | 3 |
| NTPCR | RILPL2 | 0.746655 | 3 | 0 | 3 |
| NTPCR | MAK16 | 0.746139 | 3 | 0 | 3 |
For details and further investigation, click here
