| Full name: aarF domain containing kinase 1 | Alias Symbol: FLJ39600 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 57143 | HGNC ID: HGNC:19038 | Ensembl Gene: ENSG00000063761 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ADCK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADCK1 | 57143 | 227482_at | 0.0498 | 0.9200 | |
| GSE26886 | ADCK1 | 57143 | 227482_at | 0.0275 | 0.8800 | |
| GSE45670 | ADCK1 | 57143 | 227482_at | 0.2187 | 0.0842 | |
| GSE53622 | ADCK1 | 57143 | 33647 | 0.0309 | 0.6789 | |
| GSE53624 | ADCK1 | 57143 | 33647 | -0.0240 | 0.7016 | |
| GSE63941 | ADCK1 | 57143 | 227482_at | 0.2939 | 0.4127 | |
| GSE77861 | ADCK1 | 57143 | 227482_at | -0.2097 | 0.1071 | |
| GSE97050 | ADCK1 | 57143 | A_23_P25945 | 0.0775 | 0.8115 | |
| SRP007169 | ADCK1 | 57143 | RNAseq | -0.1826 | 0.7517 | |
| SRP064894 | ADCK1 | 57143 | RNAseq | 0.8169 | 0.0009 | |
| SRP133303 | ADCK1 | 57143 | RNAseq | 0.0572 | 0.8014 | |
| SRP159526 | ADCK1 | 57143 | RNAseq | 0.1492 | 0.6914 | |
| SRP193095 | ADCK1 | 57143 | RNAseq | -0.0221 | 0.8621 | |
| SRP219564 | ADCK1 | 57143 | RNAseq | 0.5226 | 0.2015 | |
| TCGA | ADCK1 | 57143 | RNAseq | -0.0501 | 0.4564 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADCK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADCK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADCK1 | 57143 | 7 | 3 | 20 | |
| GSE20123 | ADCK1 | 57143 | 7 | 3 | 20 | |
| GSE43470 | ADCK1 | 57143 | 8 | 3 | 32 | |
| GSE46452 | ADCK1 | 57143 | 16 | 3 | 40 | |
| GSE47630 | ADCK1 | 57143 | 11 | 8 | 21 | |
| GSE54993 | ADCK1 | 57143 | 3 | 8 | 59 | |
| GSE54994 | ADCK1 | 57143 | 19 | 4 | 30 | |
| GSE60625 | ADCK1 | 57143 | 0 | 2 | 9 | |
| GSE74703 | ADCK1 | 57143 | 7 | 3 | 26 | |
| GSE74704 | ADCK1 | 57143 | 3 | 3 | 14 | |
| TCGA | ADCK1 | 57143 | 31 | 16 | 49 |
Total number of gains: 112; Total number of losses: 56; Total Number of normals: 320.
Somatic mutations of ADCK1:
Generating mutation plots.
Highly correlated genes for ADCK1:
Showing top 20/160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADCK1 | SKI | 0.839738 | 3 | 0 | 3 |
| ADCK1 | GORASP1 | 0.829512 | 3 | 0 | 3 |
| ADCK1 | C1orf159 | 0.82627 | 3 | 0 | 3 |
| ADCK1 | PTPN23 | 0.806094 | 3 | 0 | 3 |
| ADCK1 | CLASRP | 0.78478 | 3 | 0 | 3 |
| ADCK1 | ARID1A | 0.781635 | 3 | 0 | 3 |
| ADCK1 | ACSF2 | 0.780183 | 3 | 0 | 3 |
| ADCK1 | ADRB1 | 0.771076 | 3 | 0 | 3 |
| ADCK1 | GSK3A | 0.771052 | 3 | 0 | 3 |
| ADCK1 | ZNF76 | 0.767111 | 3 | 0 | 3 |
| ADCK1 | NDUFS3 | 0.763914 | 3 | 0 | 3 |
| ADCK1 | XRCC1 | 0.760218 | 3 | 0 | 3 |
| ADCK1 | MED25 | 0.7574 | 3 | 0 | 3 |
| ADCK1 | VPS28 | 0.756185 | 3 | 0 | 3 |
| ADCK1 | ATAT1 | 0.75547 | 3 | 0 | 3 |
| ADCK1 | TSEN34 | 0.750684 | 3 | 0 | 3 |
| ADCK1 | ZNF274 | 0.748153 | 3 | 0 | 3 |
| ADCK1 | TMEM115 | 0.744292 | 4 | 0 | 4 |
| ADCK1 | PRCC | 0.741776 | 3 | 0 | 3 |
| ADCK1 | USP21 | 0.741693 | 3 | 0 | 3 |
For details and further investigation, click here
