| Full name: mitochondrial ribosomal protein L11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 65003 | HGNC ID: HGNC:14042 | Ensembl Gene: ENSG00000174547 | OMIM ID: 611826 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPL11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL11 | 65003 | 219162_s_at | 0.4889 | 0.2089 | |
| GSE20347 | MRPL11 | 65003 | 219162_s_at | 0.4706 | 0.0163 | |
| GSE23400 | MRPL11 | 65003 | 219162_s_at | 0.1624 | 0.0112 | |
| GSE26886 | MRPL11 | 65003 | 219162_s_at | -0.0418 | 0.8530 | |
| GSE29001 | MRPL11 | 65003 | 219162_s_at | 0.5270 | 0.1501 | |
| GSE38129 | MRPL11 | 65003 | 219162_s_at | 0.4350 | 0.0018 | |
| GSE45670 | MRPL11 | 65003 | 219162_s_at | 0.1842 | 0.3426 | |
| GSE53622 | MRPL11 | 65003 | 76630 | 0.5796 | 0.0000 | |
| GSE53624 | MRPL11 | 65003 | 76630 | 0.7954 | 0.0000 | |
| GSE63941 | MRPL11 | 65003 | 219162_s_at | 1.2780 | 0.0294 | |
| GSE77861 | MRPL11 | 65003 | 219162_s_at | 0.3111 | 0.2084 | |
| GSE97050 | MRPL11 | 65003 | A_33_P3228959 | 0.4655 | 0.2470 | |
| SRP007169 | MRPL11 | 65003 | RNAseq | 0.2210 | 0.4995 | |
| SRP008496 | MRPL11 | 65003 | RNAseq | 0.3164 | 0.1430 | |
| SRP064894 | MRPL11 | 65003 | RNAseq | 0.3802 | 0.2190 | |
| SRP133303 | MRPL11 | 65003 | RNAseq | 0.7069 | 0.0002 | |
| SRP159526 | MRPL11 | 65003 | RNAseq | 0.5464 | 0.0267 | |
| SRP193095 | MRPL11 | 65003 | RNAseq | 0.0206 | 0.9003 | |
| SRP219564 | MRPL11 | 65003 | RNAseq | 0.2898 | 0.4979 | |
| TCGA | MRPL11 | 65003 | RNAseq | 0.2251 | 0.0004 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MRPL11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL11 | 65003 | 9 | 4 | 17 | |
| GSE20123 | MRPL11 | 65003 | 9 | 4 | 17 | |
| GSE43470 | MRPL11 | 65003 | 6 | 1 | 36 | |
| GSE46452 | MRPL11 | 65003 | 12 | 3 | 44 | |
| GSE47630 | MRPL11 | 65003 | 9 | 4 | 27 | |
| GSE54993 | MRPL11 | 65003 | 3 | 0 | 67 | |
| GSE54994 | MRPL11 | 65003 | 9 | 5 | 39 | |
| GSE60625 | MRPL11 | 65003 | 0 | 3 | 8 | |
| GSE74703 | MRPL11 | 65003 | 4 | 0 | 32 | |
| GSE74704 | MRPL11 | 65003 | 7 | 2 | 11 | |
| TCGA | MRPL11 | 65003 | 26 | 6 | 64 |
Total number of gains: 94; Total number of losses: 32; Total Number of normals: 362.
Somatic mutations of MRPL11:
Generating mutation plots.
Highly correlated genes for MRPL11:
Showing top 20/1412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL11 | RAB1B | 0.817572 | 3 | 0 | 3 |
| MRPL11 | INTS10 | 0.809993 | 3 | 0 | 3 |
| MRPL11 | PDPR | 0.807583 | 3 | 0 | 3 |
| MRPL11 | TMEM41A | 0.800305 | 3 | 0 | 3 |
| MRPL11 | LSM1 | 0.784193 | 3 | 0 | 3 |
| MRPL11 | TRUB1 | 0.77928 | 3 | 0 | 3 |
| MRPL11 | TRAF7 | 0.777081 | 3 | 0 | 3 |
| MRPL11 | ZSCAN21 | 0.770273 | 3 | 0 | 3 |
| MRPL11 | EMILIN2 | 0.767901 | 3 | 0 | 3 |
| MRPL11 | TBRG4 | 0.75833 | 4 | 0 | 4 |
| MRPL11 | ZNF484 | 0.75713 | 3 | 0 | 3 |
| MRPL11 | SLC35B2 | 0.753538 | 3 | 0 | 3 |
| MRPL11 | ARMC10 | 0.748144 | 5 | 0 | 5 |
| MRPL11 | ZC3HC1 | 0.743775 | 5 | 0 | 5 |
| MRPL11 | SCNM1 | 0.742044 | 3 | 0 | 3 |
| MRPL11 | RRP1B | 0.741012 | 3 | 0 | 3 |
| MRPL11 | NUP88 | 0.73302 | 3 | 0 | 3 |
| MRPL11 | GLUD1 | 0.72659 | 3 | 0 | 3 |
| MRPL11 | PTCD1 | 0.723632 | 3 | 0 | 3 |
| MRPL11 | ATXN7L3B | 0.719228 | 3 | 0 | 3 |
For details and further investigation, click here
