| Full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 | Alias Symbol: BAF155|SRG3|Rsc8|CRACC1 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 6599 | HGNC ID: HGNC:11104 | Ensembl Gene: ENSG00000173473 | OMIM ID: 601732 |
| Drug and gene relationship at DGIdb | |||
Expression of SMARCC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMARCC1 | 6599 | 201074_at | 0.3996 | 0.2968 | |
| GSE20347 | SMARCC1 | 6599 | 201074_at | -0.1718 | 0.3418 | |
| GSE23400 | SMARCC1 | 6599 | 201074_at | 0.0602 | 0.2847 | |
| GSE26886 | SMARCC1 | 6599 | 201074_at | 0.1221 | 0.5851 | |
| GSE29001 | SMARCC1 | 6599 | 201074_at | -0.1275 | 0.4744 | |
| GSE38129 | SMARCC1 | 6599 | 201074_at | 0.0044 | 0.9763 | |
| GSE45670 | SMARCC1 | 6599 | 201074_at | -0.0252 | 0.8605 | |
| GSE53622 | SMARCC1 | 6599 | 61999 | -0.1138 | 0.0523 | |
| GSE53624 | SMARCC1 | 6599 | 112975 | -0.0064 | 0.9429 | |
| GSE63941 | SMARCC1 | 6599 | 201074_at | -0.0770 | 0.8339 | |
| GSE77861 | SMARCC1 | 6599 | 201074_at | -0.1230 | 0.6673 | |
| GSE97050 | SMARCC1 | 6599 | A_23_P83453 | -0.2061 | 0.3192 | |
| SRP007169 | SMARCC1 | 6599 | RNAseq | 0.8165 | 0.0616 | |
| SRP008496 | SMARCC1 | 6599 | RNAseq | 0.8800 | 0.0009 | |
| SRP064894 | SMARCC1 | 6599 | RNAseq | -0.1149 | 0.4138 | |
| SRP133303 | SMARCC1 | 6599 | RNAseq | -0.0317 | 0.8255 | |
| SRP159526 | SMARCC1 | 6599 | RNAseq | 0.1097 | 0.6460 | |
| SRP193095 | SMARCC1 | 6599 | RNAseq | -0.0966 | 0.3136 | |
| SRP219564 | SMARCC1 | 6599 | RNAseq | -0.4426 | 0.1462 | |
| TCGA | SMARCC1 | 6599 | RNAseq | 0.0061 | 0.8874 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMARCC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMARCC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMARCC1 | 6599 | 0 | 18 | 12 | |
| GSE20123 | SMARCC1 | 6599 | 0 | 19 | 11 | |
| GSE43470 | SMARCC1 | 6599 | 0 | 19 | 24 | |
| GSE46452 | SMARCC1 | 6599 | 2 | 17 | 40 | |
| GSE47630 | SMARCC1 | 6599 | 2 | 23 | 15 | |
| GSE54993 | SMARCC1 | 6599 | 6 | 2 | 62 | |
| GSE54994 | SMARCC1 | 6599 | 0 | 36 | 17 | |
| GSE60625 | SMARCC1 | 6599 | 5 | 0 | 6 | |
| GSE74703 | SMARCC1 | 6599 | 0 | 15 | 21 | |
| GSE74704 | SMARCC1 | 6599 | 0 | 12 | 8 | |
| TCGA | SMARCC1 | 6599 | 0 | 76 | 20 |
Total number of gains: 15; Total number of losses: 237; Total Number of normals: 236.
Somatic mutations of SMARCC1:
Generating mutation plots.
Highly correlated genes for SMARCC1:
Showing top 20/226 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMARCC1 | CSNK2B | 0.82144 | 3 | 0 | 3 |
| SMARCC1 | SLAIN1 | 0.799159 | 3 | 0 | 3 |
| SMARCC1 | ABHD16A | 0.794343 | 3 | 0 | 3 |
| SMARCC1 | THADA | 0.756296 | 3 | 0 | 3 |
| SMARCC1 | DEK | 0.750506 | 3 | 0 | 3 |
| SMARCC1 | TP53I11 | 0.74067 | 3 | 0 | 3 |
| SMARCC1 | ZNF564 | 0.737019 | 3 | 0 | 3 |
| SMARCC1 | CUL7 | 0.735654 | 3 | 0 | 3 |
| SMARCC1 | TSEN34 | 0.730671 | 4 | 0 | 3 |
| SMARCC1 | DDX18 | 0.730292 | 3 | 0 | 3 |
| SMARCC1 | THAP7 | 0.728281 | 3 | 0 | 3 |
| SMARCC1 | C6orf136 | 0.71765 | 4 | 0 | 4 |
| SMARCC1 | MRPS18B | 0.708358 | 4 | 0 | 3 |
| SMARCC1 | KANSL2 | 0.708273 | 3 | 0 | 3 |
| SMARCC1 | MIS18A | 0.704207 | 3 | 0 | 3 |
| SMARCC1 | ALG6 | 0.704154 | 3 | 0 | 3 |
| SMARCC1 | SLC39A7 | 0.6979 | 3 | 0 | 3 |
| SMARCC1 | EED | 0.69553 | 3 | 0 | 3 |
| SMARCC1 | PEPD | 0.691017 | 4 | 0 | 3 |
| SMARCC1 | TRAP1 | 0.690883 | 3 | 0 | 3 |
For details and further investigation, click here
