| Full name: transmembrane and coiled-coil domains 2 | Alias Symbol: dJ39G22.2 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 127391 | HGNC ID: HGNC:23312 | Ensembl Gene: ENSG00000188800 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMCO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMCO2 | 127391 | 231264_at | 0.0149 | 0.9661 | |
| GSE26886 | TMCO2 | 127391 | 231264_at | -0.1188 | 0.2490 | |
| GSE45670 | TMCO2 | 127391 | 231264_at | 0.1019 | 0.3203 | |
| GSE53622 | TMCO2 | 127391 | 17906 | -0.3324 | 0.0054 | |
| GSE53624 | TMCO2 | 127391 | 17906 | -0.5803 | 0.0000 | |
| GSE63941 | TMCO2 | 127391 | 231264_at | -0.0969 | 0.4549 | |
| GSE77861 | TMCO2 | 127391 | 231264_at | -0.0463 | 0.5439 | |
| GSE97050 | TMCO2 | 127391 | A_32_P87649 | -0.2358 | 0.3593 | |
| TCGA | TMCO2 | 127391 | RNAseq | 0.8630 | 0.5948 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMCO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMCO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMCO2 | 127391 | 3 | 4 | 23 | |
| GSE20123 | TMCO2 | 127391 | 2 | 3 | 25 | |
| GSE43470 | TMCO2 | 127391 | 7 | 2 | 34 | |
| GSE46452 | TMCO2 | 127391 | 4 | 1 | 54 | |
| GSE47630 | TMCO2 | 127391 | 9 | 2 | 29 | |
| GSE54993 | TMCO2 | 127391 | 0 | 1 | 69 | |
| GSE54994 | TMCO2 | 127391 | 13 | 2 | 38 | |
| GSE60625 | TMCO2 | 127391 | 0 | 0 | 11 | |
| GSE74703 | TMCO2 | 127391 | 6 | 1 | 29 | |
| GSE74704 | TMCO2 | 127391 | 1 | 0 | 19 | |
| TCGA | TMCO2 | 127391 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 32; Total Number of normals: 395.
Somatic mutations of TMCO2:
Generating mutation plots.
Highly correlated genes for TMCO2:
Showing top 20/76 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMCO2 | CDK20 | 0.696093 | 3 | 0 | 3 |
| TMCO2 | ASB12 | 0.691863 | 3 | 0 | 3 |
| TMCO2 | PGM5 | 0.688277 | 3 | 0 | 3 |
| TMCO2 | ZSWIM3 | 0.673636 | 3 | 0 | 3 |
| TMCO2 | ASB16 | 0.664356 | 3 | 0 | 3 |
| TMCO2 | RGN | 0.662821 | 3 | 0 | 3 |
| TMCO2 | PID1 | 0.661311 | 4 | 0 | 3 |
| TMCO2 | CDK15 | 0.656238 | 3 | 0 | 3 |
| TMCO2 | TMEM8B | 0.649071 | 3 | 0 | 3 |
| TMCO2 | ACSS1 | 0.645144 | 3 | 0 | 3 |
| TMCO2 | TOX | 0.644804 | 3 | 0 | 3 |
| TMCO2 | ZNF415 | 0.643471 | 3 | 0 | 3 |
| TMCO2 | LINC01111 | 0.637516 | 5 | 0 | 4 |
| TMCO2 | SV2C | 0.632467 | 4 | 0 | 4 |
| TMCO2 | CNN1 | 0.627586 | 3 | 0 | 3 |
| TMCO2 | UGT2B28 | 0.626769 | 3 | 0 | 3 |
| TMCO2 | GLYCTK | 0.6232 | 4 | 0 | 3 |
| TMCO2 | ADD1 | 0.618349 | 3 | 0 | 3 |
| TMCO2 | PER3 | 0.616153 | 3 | 0 | 3 |
| TMCO2 | HSD11B1L | 0.611567 | 3 | 0 | 3 |
For details and further investigation, click here
