| Full name: phosphoglucomutase 5 | Alias Symbol: PGMRP | ||
| Type: protein-coding gene | Cytoband: 9q21.11 | ||
| Entrez ID: 5239 | HGNC ID: HGNC:8908 | Ensembl Gene: ENSG00000154330 | OMIM ID: 600981 |
| Drug and gene relationship at DGIdb | |||
Expression of PGM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PGM5 | 5239 | 226303_at | -3.4354 | 0.0956 | |
| GSE20347 | PGM5 | 5239 | 208491_s_at | -0.1453 | 0.0734 | |
| GSE23400 | PGM5 | 5239 | 208491_s_at | -0.6999 | 0.0000 | |
| GSE26886 | PGM5 | 5239 | 208491_s_at | 0.0562 | 0.6249 | |
| GSE29001 | PGM5 | 5239 | 208491_s_at | -0.3234 | 0.0520 | |
| GSE38129 | PGM5 | 5239 | 208491_s_at | -0.6330 | 0.0000 | |
| GSE45670 | PGM5 | 5239 | 226303_at | -4.9865 | 0.0000 | |
| GSE53622 | PGM5 | 5239 | 70131 | -4.1021 | 0.0000 | |
| GSE53624 | PGM5 | 5239 | 70131 | -3.8865 | 0.0000 | |
| GSE63941 | PGM5 | 5239 | 208491_s_at | 0.0948 | 0.6587 | |
| GSE77861 | PGM5 | 5239 | 208491_s_at | -0.1996 | 0.1414 | |
| GSE97050 | PGM5 | 5239 | A_24_P254949 | -1.2266 | 0.1287 | |
| SRP064894 | PGM5 | 5239 | RNAseq | -1.2955 | 0.0184 | |
| SRP133303 | PGM5 | 5239 | RNAseq | -1.9183 | 0.0375 | |
| SRP159526 | PGM5 | 5239 | RNAseq | -2.2677 | 0.0000 | |
| SRP219564 | PGM5 | 5239 | RNAseq | -1.5312 | 0.2295 | |
| TCGA | PGM5 | 5239 | RNAseq | -1.4112 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by PGM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PGM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PGM5 | 5239 | 7 | 10 | 13 | |
| GSE20123 | PGM5 | 5239 | 7 | 11 | 12 | |
| GSE43470 | PGM5 | 5239 | 6 | 5 | 32 | |
| GSE46452 | PGM5 | 5239 | 6 | 15 | 38 | |
| GSE47630 | PGM5 | 5239 | 1 | 19 | 20 | |
| GSE54993 | PGM5 | 5239 | 5 | 1 | 64 | |
| GSE54994 | PGM5 | 5239 | 4 | 13 | 36 | |
| GSE60625 | PGM5 | 5239 | 0 | 0 | 11 | |
| GSE74703 | PGM5 | 5239 | 5 | 4 | 27 | |
| GSE74704 | PGM5 | 5239 | 3 | 7 | 10 | |
| TCGA | PGM5 | 5239 | 21 | 46 | 29 |
Total number of gains: 65; Total number of losses: 131; Total Number of normals: 292.
Somatic mutations of PGM5:
Generating mutation plots.
Highly correlated genes for PGM5:
Showing top 20/1486 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PGM5 | NEGR1 | 0.909552 | 5 | 0 | 5 |
| PGM5 | RBPMS2 | 0.905735 | 6 | 0 | 6 |
| PGM5 | ANGPTL1 | 0.89466 | 5 | 0 | 5 |
| PGM5 | CYP21A2 | 0.872843 | 3 | 0 | 3 |
| PGM5 | RBFOX3 | 0.872362 | 3 | 0 | 3 |
| PGM5 | XKR4 | 0.859541 | 5 | 0 | 5 |
| PGM5 | NEXN | 0.850879 | 6 | 0 | 6 |
| PGM5 | ASB5 | 0.841679 | 5 | 0 | 5 |
| PGM5 | RAB9B | 0.836483 | 6 | 0 | 6 |
| PGM5 | CLEC3B | 0.827795 | 3 | 0 | 3 |
| PGM5 | PTCHD1 | 0.826896 | 5 | 0 | 5 |
| PGM5 | MIR100HG | 0.826571 | 4 | 0 | 4 |
| PGM5 | MAMDC2 | 0.825931 | 6 | 0 | 5 |
| PGM5 | ADCY5 | 0.821218 | 5 | 0 | 5 |
| PGM5 | MRVI1 | 0.814456 | 6 | 0 | 5 |
| PGM5 | CHRDL1 | 0.813117 | 7 | 0 | 7 |
| PGM5 | ATP1A2 | 0.812597 | 10 | 0 | 9 |
| PGM5 | PDE5A | 0.809161 | 9 | 0 | 9 |
| PGM5 | SCN7A | 0.806886 | 9 | 0 | 8 |
| PGM5 | KCNT2 | 0.806839 | 5 | 0 | 5 |
For details and further investigation, click here
