UGT2B28

 

Full name: UDP glucuronosyltransferase family 2 member B28 Alias Symbol: 
Type: protein-coding gene Cytoband: 4q13.2
Entrez ID: 54490 HGNC ID: HGNC:13479 Ensembl Gene: ENSG00000135226 OMIM ID: 606497
Drug and gene relationship at DGIdb

 

Expression of UGT2B28:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UGT2B28 54490 211682_x_at 0.0190 0.9479
GSE20347 UGT2B28 54490 211682_x_at 0.0944 0.5295
GSE23400 UGT2B28 54490 211682_x_at 0.0803 0.0484
GSE26886 UGT2B28 54490 211682_x_at -0.0688 0.6813
GSE29001 UGT2B28 54490 211682_x_at -0.1268 0.4371
GSE38129 UGT2B28 54490 211682_x_at 0.0097 0.9413
GSE45670 UGT2B28 54490 211682_x_at 0.2024 0.5545
GSE53622 UGT2B28 54490 108945 0.3154 0.0324
GSE53624 UGT2B28 54490 108945 0.3735 0.0105
GSE63941 UGT2B28 54490 211682_x_at 0.2716 0.1773
GSE77861 UGT2B28 54490 211682_x_at -0.1162 0.2335

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by UGT2B28 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of UGT2B28:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UGT2B28 54490 0 10 20
GSE20123 UGT2B28 54490 0 11 19
GSE43470 UGT2B28 54490 0 13 30
GSE46452 UGT2B28 54490 2 35 22
GSE47630 UGT2B28 54490 1 18 21
GSE54993 UGT2B28 54490 7 0 63
GSE54994 UGT2B28 54490 1 9 43
GSE60625 UGT2B28 54490 0 0 11
GSE74703 UGT2B28 54490 0 11 25
GSE74704 UGT2B28 54490 0 7 13
TCGA UGT2B28 54490 18 26 52

Total number of gains: 29; Total number of losses: 140; Total Number of normals: 319.  


 

Somatic mutations of UGT2B28:

 

Generating mutation plots.

 

Highly correlated genes for UGT2B28:

 

Showing top 20/521 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UGT2B28FABP70.82288303
UGT2B28TNXB0.69776303
UGT2B28SPX0.69035303
UGT2B28VGLL20.683481303
UGT2B28MUC130.6786303
UGT2B28CDC25C0.677494303
UGT2B28DTNA0.675473303
UGT2B28KCNS10.67512403
UGT2B28TERT0.672894303
UGT2B28ARPP210.671771403
UGT2B28CDH150.670986303
UGT2B28PDE3B0.668727403
UGT2B28ZNF2870.667218303
UGT2B28CACNG10.66644404
UGT2B28TAF6L0.665628404
UGT2B28CCDC1570.664275303
UGT2B28VN1R10.663853403
UGT2B28KRT380.663759303
UGT2B28PRPS1L10.660414504
UGT2B28POU6F10.657644303

For details and further investigation, click here