| Full name: acyl-CoA synthetase short chain family member 1 | Alias Symbol: dJ568C11.3|AceCS2L|MGC33843 | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 84532 | HGNC ID: HGNC:16091 | Ensembl Gene: ENSG00000154930 | OMIM ID: 614355 |
| Drug and gene relationship at DGIdb | |||
Expression of ACSS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACSS1 | 84532 | 224882_at | 0.1577 | 0.8364 | |
| GSE26886 | ACSS1 | 84532 | 224882_at | 0.0649 | 0.8113 | |
| GSE45670 | ACSS1 | 84532 | 224882_at | -0.0855 | 0.7562 | |
| GSE53622 | ACSS1 | 84532 | 24132 | -0.2245 | 0.1272 | |
| GSE53624 | ACSS1 | 84532 | 24132 | 0.0410 | 0.7198 | |
| GSE63941 | ACSS1 | 84532 | 224882_at | 0.1008 | 0.8641 | |
| GSE77861 | ACSS1 | 84532 | 224882_at | 0.0674 | 0.6968 | |
| GSE97050 | ACSS1 | 84532 | A_33_P3422404 | -0.3588 | 0.1471 | |
| SRP007169 | ACSS1 | 84532 | RNAseq | 0.5106 | 0.1802 | |
| SRP008496 | ACSS1 | 84532 | RNAseq | 0.7832 | 0.0309 | |
| SRP064894 | ACSS1 | 84532 | RNAseq | 0.0615 | 0.8091 | |
| SRP133303 | ACSS1 | 84532 | RNAseq | -0.2292 | 0.2942 | |
| SRP159526 | ACSS1 | 84532 | RNAseq | 1.3209 | 0.0005 | |
| SRP193095 | ACSS1 | 84532 | RNAseq | -0.2068 | 0.4509 | |
| SRP219564 | ACSS1 | 84532 | RNAseq | 0.2454 | 0.6361 | |
| TCGA | ACSS1 | 84532 | RNAseq | -0.4775 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ACSS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACSS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACSS1 | 84532 | 12 | 2 | 16 | |
| GSE20123 | ACSS1 | 84532 | 12 | 2 | 16 | |
| GSE43470 | ACSS1 | 84532 | 11 | 1 | 31 | |
| GSE46452 | ACSS1 | 84532 | 27 | 1 | 31 | |
| GSE47630 | ACSS1 | 84532 | 17 | 4 | 19 | |
| GSE54993 | ACSS1 | 84532 | 0 | 17 | 53 | |
| GSE54994 | ACSS1 | 84532 | 27 | 1 | 25 | |
| GSE60625 | ACSS1 | 84532 | 0 | 0 | 11 | |
| GSE74703 | ACSS1 | 84532 | 10 | 1 | 25 | |
| GSE74704 | ACSS1 | 84532 | 7 | 1 | 12 | |
| TCGA | ACSS1 | 84532 | 44 | 9 | 43 |
Total number of gains: 167; Total number of losses: 39; Total Number of normals: 282.
Somatic mutations of ACSS1:
Generating mutation plots.
Highly correlated genes for ACSS1:
Showing top 20/75 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACSS1 | COQ10A | 0.662498 | 4 | 0 | 3 |
| ACSS1 | PDE7B | 0.645905 | 3 | 0 | 3 |
| ACSS1 | TMCO2 | 0.645144 | 3 | 0 | 3 |
| ACSS1 | PANK4 | 0.641809 | 3 | 0 | 3 |
| ACSS1 | TTC19 | 0.634496 | 4 | 0 | 3 |
| ACSS1 | GGNBP2 | 0.629624 | 3 | 0 | 3 |
| ACSS1 | ZBTB22 | 0.622771 | 3 | 0 | 3 |
| ACSS1 | L3MBTL3 | 0.622307 | 3 | 0 | 3 |
| ACSS1 | TRIM2 | 0.619919 | 4 | 0 | 3 |
| ACSS1 | VPS39 | 0.614221 | 3 | 0 | 3 |
| ACSS1 | LIG3 | 0.605147 | 4 | 0 | 4 |
| ACSS1 | C2orf49 | 0.603747 | 3 | 0 | 3 |
| ACSS1 | GSX1 | 0.597099 | 3 | 0 | 3 |
| ACSS1 | ECSIT | 0.594521 | 4 | 0 | 4 |
| ACSS1 | FAM122B | 0.593592 | 4 | 0 | 3 |
| ACSS1 | HNRNPA0 | 0.592364 | 3 | 0 | 3 |
| ACSS1 | MSI2 | 0.585951 | 5 | 0 | 4 |
| ACSS1 | MGAT3 | 0.585376 | 5 | 0 | 4 |
| ACSS1 | C2CD5 | 0.581389 | 4 | 0 | 3 |
| ACSS1 | MYEF2 | 0.580271 | 3 | 0 | 3 |
For details and further investigation, click here
