| Full name: transmembrane protein 8B | Alias Symbol: NAG-5|NGX6 | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 51754 | HGNC ID: HGNC:21427 | Ensembl Gene: ENSG00000137103 | OMIM ID: 616888 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM8B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM8B | 51754 | 207839_s_at | -0.3867 | 0.4469 | |
| GSE20347 | TMEM8B | 51754 | 207839_s_at | 0.1741 | 0.1286 | |
| GSE23400 | TMEM8B | 51754 | 207839_s_at | -0.1245 | 0.0076 | |
| GSE26886 | TMEM8B | 51754 | 229729_at | 0.0703 | 0.6278 | |
| GSE29001 | TMEM8B | 51754 | 207839_s_at | -0.0418 | 0.8665 | |
| GSE38129 | TMEM8B | 51754 | 207839_s_at | -0.0521 | 0.7461 | |
| GSE45670 | TMEM8B | 51754 | 229729_at | -0.1876 | 0.1592 | |
| GSE53622 | TMEM8B | 51754 | 242 | -0.4990 | 0.0001 | |
| GSE53624 | TMEM8B | 51754 | 242 | -0.2652 | 0.0072 | |
| GSE63941 | TMEM8B | 51754 | 207839_s_at | -0.9804 | 0.0185 | |
| GSE77861 | TMEM8B | 51754 | 229729_at | -0.1551 | 0.1304 | |
| GSE97050 | TMEM8B | 51754 | A_24_P317827 | -0.5882 | 0.2300 | |
| SRP007169 | TMEM8B | 51754 | RNAseq | 0.0740 | 0.9112 | |
| SRP008496 | TMEM8B | 51754 | RNAseq | 1.0637 | 0.0660 | |
| SRP064894 | TMEM8B | 51754 | RNAseq | -0.0596 | 0.8616 | |
| SRP133303 | TMEM8B | 51754 | RNAseq | -0.7650 | 0.0053 | |
| SRP159526 | TMEM8B | 51754 | RNAseq | -0.1453 | 0.5725 | |
| SRP193095 | TMEM8B | 51754 | RNAseq | 0.0638 | 0.8083 | |
| SRP219564 | TMEM8B | 51754 | RNAseq | -0.2603 | 0.6668 | |
| TCGA | TMEM8B | 51754 | RNAseq | -0.6765 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM8B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM8B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM8B | 51754 | 3 | 12 | 15 | |
| GSE20123 | TMEM8B | 51754 | 3 | 12 | 15 | |
| GSE43470 | TMEM8B | 51754 | 3 | 10 | 30 | |
| GSE46452 | TMEM8B | 51754 | 6 | 15 | 38 | |
| GSE47630 | TMEM8B | 51754 | 1 | 20 | 19 | |
| GSE54993 | TMEM8B | 51754 | 6 | 0 | 64 | |
| GSE54994 | TMEM8B | 51754 | 5 | 12 | 36 | |
| GSE60625 | TMEM8B | 51754 | 0 | 0 | 11 | |
| GSE74703 | TMEM8B | 51754 | 2 | 7 | 27 | |
| GSE74704 | TMEM8B | 51754 | 0 | 10 | 10 | |
| TCGA | TMEM8B | 51754 | 17 | 44 | 35 |
Total number of gains: 46; Total number of losses: 142; Total Number of normals: 300.
Somatic mutations of TMEM8B:
Generating mutation plots.
Highly correlated genes for TMEM8B:
Showing top 20/616 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM8B | SAMD14 | 0.766226 | 3 | 0 | 3 |
| TMEM8B | SIX6 | 0.744574 | 3 | 0 | 3 |
| TMEM8B | CSN3 | 0.738848 | 3 | 0 | 3 |
| TMEM8B | NRXN3 | 0.729883 | 5 | 0 | 5 |
| TMEM8B | SLC17A7 | 0.724737 | 4 | 0 | 3 |
| TMEM8B | MUC8 | 0.71814 | 3 | 0 | 3 |
| TMEM8B | PRR34 | 0.716088 | 3 | 0 | 3 |
| TMEM8B | GRIK3 | 0.707635 | 3 | 0 | 3 |
| TMEM8B | DHDDS | 0.707183 | 3 | 0 | 3 |
| TMEM8B | GIPC3 | 0.705524 | 4 | 0 | 4 |
| TMEM8B | ZNF358 | 0.705111 | 6 | 0 | 6 |
| TMEM8B | CACNG2 | 0.704814 | 3 | 0 | 3 |
| TMEM8B | ESRRG | 0.703254 | 5 | 0 | 5 |
| TMEM8B | HS6ST3 | 0.702654 | 5 | 0 | 3 |
| TMEM8B | HMHB1 | 0.698755 | 4 | 0 | 4 |
| TMEM8B | HABP4 | 0.695948 | 6 | 0 | 5 |
| TMEM8B | BCL2 | 0.69561 | 6 | 0 | 6 |
| TMEM8B | FIBIN | 0.695552 | 3 | 0 | 3 |
| TMEM8B | PGM5-AS1 | 0.693341 | 3 | 0 | 3 |
| TMEM8B | KALRN | 0.692572 | 3 | 0 | 3 |
For details and further investigation, click here
