| Full name: hydroxysteroid 11-beta dehydrogenase 1 like | Alias Symbol: SCDR10|SDR26C2|HSD1L | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 374875 | HGNC ID: HGNC:30419 | Ensembl Gene: ENSG00000167733 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HSD11B1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSD11B1L | 374875 | 228757_at | 0.5408 | 0.3371 | |
| GSE26886 | HSD11B1L | 374875 | 228757_at | -0.0894 | 0.6206 | |
| GSE45670 | HSD11B1L | 374875 | 1569905_at | -0.0837 | 0.3216 | |
| GSE53622 | HSD11B1L | 374875 | 41428 | 0.4747 | 0.0005 | |
| GSE53624 | HSD11B1L | 374875 | 41428 | 0.4691 | 0.0000 | |
| GSE63941 | HSD11B1L | 374875 | 1569905_at | -0.1935 | 0.3648 | |
| GSE77861 | HSD11B1L | 374875 | 228757_at | 0.0369 | 0.7970 | |
| GSE97050 | HSD11B1L | 374875 | A_23_P141992 | -0.2127 | 0.4656 | |
| SRP064894 | HSD11B1L | 374875 | RNAseq | 0.7402 | 0.0580 | |
| SRP133303 | HSD11B1L | 374875 | RNAseq | -0.1597 | 0.5419 | |
| SRP159526 | HSD11B1L | 374875 | RNAseq | 0.9140 | 0.0400 | |
| SRP193095 | HSD11B1L | 374875 | RNAseq | 0.2762 | 0.1751 | |
| SRP219564 | HSD11B1L | 374875 | RNAseq | -0.3026 | 0.5995 | |
| TCGA | HSD11B1L | 374875 | RNAseq | 0.0791 | 0.6087 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HSD11B1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSD11B1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSD11B1L | 374875 | 5 | 3 | 22 | |
| GSE20123 | HSD11B1L | 374875 | 4 | 2 | 24 | |
| GSE43470 | HSD11B1L | 374875 | 2 | 6 | 35 | |
| GSE46452 | HSD11B1L | 374875 | 47 | 1 | 11 | |
| GSE47630 | HSD11B1L | 374875 | 5 | 7 | 28 | |
| GSE54993 | HSD11B1L | 374875 | 16 | 3 | 51 | |
| GSE54994 | HSD11B1L | 374875 | 6 | 16 | 31 | |
| GSE60625 | HSD11B1L | 374875 | 9 | 0 | 2 | |
| GSE74703 | HSD11B1L | 374875 | 2 | 4 | 30 | |
| GSE74704 | HSD11B1L | 374875 | 1 | 2 | 17 | |
| TCGA | HSD11B1L | 374875 | 10 | 18 | 68 |
Total number of gains: 107; Total number of losses: 62; Total Number of normals: 319.
Somatic mutations of HSD11B1L:
Generating mutation plots.
Highly correlated genes for HSD11B1L:
Showing top 20/44 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSD11B1L | TBC1D13 | 0.75031 | 3 | 0 | 3 |
| HSD11B1L | LRRC6 | 0.706427 | 3 | 0 | 3 |
| HSD11B1L | BCL7B | 0.704993 | 3 | 0 | 3 |
| HSD11B1L | MANBAL | 0.676616 | 4 | 0 | 4 |
| HSD11B1L | PELI3 | 0.673981 | 3 | 0 | 3 |
| HSD11B1L | EFR3A | 0.669943 | 3 | 0 | 3 |
| HSD11B1L | TBC1D10B | 0.668397 | 3 | 0 | 3 |
| HSD11B1L | PLA2G5 | 0.663334 | 3 | 0 | 3 |
| HSD11B1L | WNK2 | 0.65192 | 3 | 0 | 3 |
| HSD11B1L | PI4KB | 0.64646 | 3 | 0 | 3 |
| HSD11B1L | HTR1B | 0.646013 | 3 | 0 | 3 |
| HSD11B1L | CADM4 | 0.619627 | 3 | 0 | 3 |
| HSD11B1L | LTBP3 | 0.614612 | 4 | 0 | 3 |
| HSD11B1L | TMCO2 | 0.611567 | 3 | 0 | 3 |
| HSD11B1L | ZNF428 | 0.606431 | 4 | 0 | 3 |
| HSD11B1L | ZNF446 | 0.605171 | 3 | 0 | 3 |
| HSD11B1L | FIZ1 | 0.602748 | 3 | 0 | 3 |
| HSD11B1L | PCBD1 | 0.599377 | 4 | 0 | 3 |
| HSD11B1L | BAZ2A | 0.597495 | 3 | 0 | 3 |
| HSD11B1L | SLC34A1 | 0.590071 | 4 | 0 | 3 |
For details and further investigation, click here
