| Full name: transmembrane protein 143 | Alias Symbol: FLJ10922 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 55260 | HGNC ID: HGNC:25603 | Ensembl Gene: ENSG00000161558 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM143:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM143 | 55260 | 222905_s_at | 0.0442 | 0.8832 | |
| GSE20347 | TMEM143 | 55260 | 219589_s_at | 0.0678 | 0.4262 | |
| GSE23400 | TMEM143 | 55260 | 219589_s_at | -0.0236 | 0.3350 | |
| GSE26886 | TMEM143 | 55260 | 222905_s_at | 0.0967 | 0.3740 | |
| GSE29001 | TMEM143 | 55260 | 219589_s_at | 0.0698 | 0.6459 | |
| GSE38129 | TMEM143 | 55260 | 219589_s_at | -0.0246 | 0.7065 | |
| GSE45670 | TMEM143 | 55260 | 222905_s_at | 0.0526 | 0.7114 | |
| GSE53622 | TMEM143 | 55260 | 35442 | -0.0733 | 0.4896 | |
| GSE53624 | TMEM143 | 55260 | 35442 | 0.0440 | 0.6154 | |
| GSE63941 | TMEM143 | 55260 | 222905_s_at | 0.5780 | 0.0754 | |
| GSE77861 | TMEM143 | 55260 | 219589_s_at | -0.0350 | 0.8054 | |
| GSE97050 | TMEM143 | 55260 | A_24_P412976 | -0.1690 | 0.6169 | |
| SRP007169 | TMEM143 | 55260 | RNAseq | -0.3356 | 0.5569 | |
| SRP064894 | TMEM143 | 55260 | RNAseq | 0.2305 | 0.3067 | |
| SRP133303 | TMEM143 | 55260 | RNAseq | -0.1439 | 0.5232 | |
| SRP159526 | TMEM143 | 55260 | RNAseq | 0.2309 | 0.4878 | |
| SRP193095 | TMEM143 | 55260 | RNAseq | -0.0988 | 0.4699 | |
| SRP219564 | TMEM143 | 55260 | RNAseq | -0.0316 | 0.9447 | |
| TCGA | TMEM143 | 55260 | RNAseq | -0.3006 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM143 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM143:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM143 | 55260 | 4 | 4 | 22 | |
| GSE20123 | TMEM143 | 55260 | 4 | 3 | 23 | |
| GSE43470 | TMEM143 | 55260 | 4 | 11 | 28 | |
| GSE46452 | TMEM143 | 55260 | 45 | 1 | 13 | |
| GSE47630 | TMEM143 | 55260 | 9 | 6 | 25 | |
| GSE54993 | TMEM143 | 55260 | 17 | 4 | 49 | |
| GSE54994 | TMEM143 | 55260 | 4 | 14 | 35 | |
| GSE60625 | TMEM143 | 55260 | 9 | 0 | 2 | |
| GSE74703 | TMEM143 | 55260 | 4 | 7 | 25 | |
| GSE74704 | TMEM143 | 55260 | 4 | 1 | 15 | |
| TCGA | TMEM143 | 55260 | 15 | 18 | 63 |
Total number of gains: 119; Total number of losses: 69; Total Number of normals: 300.
Somatic mutations of TMEM143:
Generating mutation plots.
Highly correlated genes for TMEM143:
Showing top 20/378 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM143 | ZBTB10 | 0.763163 | 3 | 0 | 3 |
| TMEM143 | LSM14A | 0.75267 | 3 | 0 | 3 |
| TMEM143 | TEAD2 | 0.748602 | 3 | 0 | 3 |
| TMEM143 | MYL9 | 0.744851 | 3 | 0 | 3 |
| TMEM143 | COMMD5 | 0.730658 | 3 | 0 | 3 |
| TMEM143 | NCAM1 | 0.730433 | 3 | 0 | 3 |
| TMEM143 | CCDC159 | 0.713468 | 3 | 0 | 3 |
| TMEM143 | MATN4 | 0.712872 | 3 | 0 | 3 |
| TMEM143 | ADARB1 | 0.708084 | 4 | 0 | 4 |
| TMEM143 | LGI2 | 0.702315 | 5 | 0 | 5 |
| TMEM143 | ZMIZ2 | 0.69556 | 3 | 0 | 3 |
| TMEM143 | KIAA1324L | 0.694543 | 3 | 0 | 3 |
| TMEM143 | TRAPPC3 | 0.694489 | 3 | 0 | 3 |
| TMEM143 | SLC25A16 | 0.689522 | 4 | 0 | 4 |
| TMEM143 | ZNF358 | 0.685015 | 5 | 0 | 4 |
| TMEM143 | RIC8B | 0.681649 | 4 | 0 | 3 |
| TMEM143 | PREPL | 0.671041 | 3 | 0 | 3 |
| TMEM143 | WDR31 | 0.670253 | 3 | 0 | 3 |
| TMEM143 | ZNF41 | 0.6672 | 3 | 0 | 3 |
| TMEM143 | TXLNG | 0.666845 | 3 | 0 | 3 |
For details and further investigation, click here
