| Full name: neural cell adhesion molecule 1 | Alias Symbol: NCAM|CD56 | ||
| Type: protein-coding gene | Cytoband: 11q23.2 | ||
| Entrez ID: 4684 | HGNC ID: HGNC:7656 | Ensembl Gene: ENSG00000149294 | OMIM ID: 116930 |
| Drug and gene relationship at DGIdb | |||
NCAM1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05020 | Prion diseases |
Expression of NCAM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCAM1 | 4684 | 227394_at | -0.6083 | 0.5802 | |
| GSE20347 | NCAM1 | 4684 | 209968_s_at | 0.0256 | 0.8365 | |
| GSE23400 | NCAM1 | 4684 | 212843_at | -0.4937 | 0.0047 | |
| GSE26886 | NCAM1 | 4684 | 227394_at | 0.5578 | 0.0704 | |
| GSE29001 | NCAM1 | 4684 | 212843_at | -0.4887 | 0.0636 | |
| GSE38129 | NCAM1 | 4684 | 209968_s_at | -0.2484 | 0.0992 | |
| GSE45670 | NCAM1 | 4684 | 227394_at | -1.2331 | 0.0000 | |
| GSE53622 | NCAM1 | 4684 | 55824 | -2.2771 | 0.0000 | |
| GSE53624 | NCAM1 | 4684 | 31450 | -2.3243 | 0.0000 | |
| GSE63941 | NCAM1 | 4684 | 209968_s_at | 0.0317 | 0.8709 | |
| GSE77861 | NCAM1 | 4684 | 209968_s_at | -0.0967 | 0.4046 | |
| GSE97050 | NCAM1 | 4684 | A_23_P1740 | -1.4710 | 0.1176 | |
| SRP064894 | NCAM1 | 4684 | RNAseq | 0.1075 | 0.8370 | |
| SRP133303 | NCAM1 | 4684 | RNAseq | -1.9815 | 0.0000 | |
| SRP159526 | NCAM1 | 4684 | RNAseq | -0.6021 | 0.3406 | |
| SRP193095 | NCAM1 | 4684 | RNAseq | 0.4281 | 0.3484 | |
| SRP219564 | NCAM1 | 4684 | RNAseq | -0.8495 | 0.4922 | |
| TCGA | NCAM1 | 4684 | RNAseq | -1.5066 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by NCAM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCAM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCAM1 | 4684 | 0 | 13 | 17 | |
| GSE20123 | NCAM1 | 4684 | 0 | 13 | 17 | |
| GSE43470 | NCAM1 | 4684 | 2 | 6 | 35 | |
| GSE46452 | NCAM1 | 4684 | 3 | 26 | 30 | |
| GSE47630 | NCAM1 | 4684 | 2 | 19 | 19 | |
| GSE54993 | NCAM1 | 4684 | 10 | 0 | 60 | |
| GSE54994 | NCAM1 | 4684 | 5 | 19 | 29 | |
| GSE60625 | NCAM1 | 4684 | 0 | 3 | 8 | |
| GSE74703 | NCAM1 | 4684 | 1 | 4 | 31 | |
| GSE74704 | NCAM1 | 4684 | 0 | 9 | 11 | |
| TCGA | NCAM1 | 4684 | 6 | 49 | 41 |
Total number of gains: 29; Total number of losses: 161; Total Number of normals: 298.
Somatic mutations of NCAM1:
Generating mutation plots.
Highly correlated genes for NCAM1:
Showing top 20/1009 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCAM1 | ANO5 | 0.882095 | 5 | 0 | 5 |
| NCAM1 | SORCS1 | 0.879797 | 4 | 0 | 4 |
| NCAM1 | IQUB | 0.820108 | 3 | 0 | 3 |
| NCAM1 | CLEC3B | 0.819339 | 3 | 0 | 3 |
| NCAM1 | RBPMS2 | 0.817778 | 6 | 0 | 6 |
| NCAM1 | HSPB7 | 0.817602 | 8 | 0 | 8 |
| NCAM1 | PDZRN4 | 0.816845 | 9 | 0 | 8 |
| NCAM1 | CYP21A2 | 0.815888 | 3 | 0 | 3 |
| NCAM1 | MBNL1-AS1 | 0.80865 | 3 | 0 | 3 |
| NCAM1 | SH3BGR | 0.803959 | 7 | 0 | 7 |
| NCAM1 | MTURN | 0.799357 | 4 | 0 | 4 |
| NCAM1 | ANGPTL1 | 0.791338 | 6 | 0 | 6 |
| NCAM1 | MAMDC2 | 0.790695 | 5 | 0 | 5 |
| NCAM1 | DIXDC1 | 0.789988 | 8 | 0 | 8 |
| NCAM1 | MYL9 | 0.789679 | 8 | 0 | 8 |
| NCAM1 | ATP1A2 | 0.786936 | 8 | 0 | 8 |
| NCAM1 | MRGPRF | 0.786794 | 5 | 0 | 5 |
| NCAM1 | PPP1R12A | 0.78634 | 7 | 0 | 7 |
| NCAM1 | UBXN10 | 0.785955 | 5 | 0 | 4 |
| NCAM1 | INMT | 0.785603 | 5 | 0 | 5 |
For details and further investigation, click here
