| Full name: matrilin 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 8785 | HGNC ID: HGNC:6910 | Ensembl Gene: ENSG00000124159 | OMIM ID: 603897 |
| Drug and gene relationship at DGIdb | |||
Expression of MATN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MATN4 | 8785 | 207123_s_at | -0.0127 | 0.9664 | |
| GSE20347 | MATN4 | 8785 | 207123_s_at | -0.0326 | 0.6175 | |
| GSE23400 | MATN4 | 8785 | 207123_s_at | -0.0735 | 0.0105 | |
| GSE26886 | MATN4 | 8785 | 207123_s_at | 0.5028 | 0.0010 | |
| GSE29001 | MATN4 | 8785 | 207123_s_at | 0.0699 | 0.6895 | |
| GSE38129 | MATN4 | 8785 | 207123_s_at | 0.0322 | 0.6895 | |
| GSE45670 | MATN4 | 8785 | 207123_s_at | -0.2152 | 0.0060 | |
| GSE53622 | MATN4 | 8785 | 10382 | 0.2143 | 0.0007 | |
| GSE53624 | MATN4 | 8785 | 10382 | 0.3493 | 0.0000 | |
| GSE63941 | MATN4 | 8785 | 207123_s_at | 0.3631 | 0.0625 | |
| GSE77861 | MATN4 | 8785 | 207123_s_at | -0.1092 | 0.4861 | |
| GSE97050 | MATN4 | 8785 | A_33_P3210468 | -0.1997 | 0.3956 | |
| SRP219564 | MATN4 | 8785 | RNAseq | 2.0395 | 0.0004 | |
| TCGA | MATN4 | 8785 | RNAseq | -0.9487 | 0.0186 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MATN4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MATN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MATN4 | 8785 | 13 | 1 | 16 | |
| GSE20123 | MATN4 | 8785 | 13 | 1 | 16 | |
| GSE43470 | MATN4 | 8785 | 12 | 1 | 30 | |
| GSE46452 | MATN4 | 8785 | 29 | 0 | 30 | |
| GSE47630 | MATN4 | 8785 | 24 | 1 | 15 | |
| GSE54993 | MATN4 | 8785 | 0 | 17 | 53 | |
| GSE54994 | MATN4 | 8785 | 25 | 0 | 28 | |
| GSE60625 | MATN4 | 8785 | 0 | 0 | 11 | |
| GSE74703 | MATN4 | 8785 | 10 | 1 | 25 | |
| GSE74704 | MATN4 | 8785 | 9 | 0 | 11 | |
| TCGA | MATN4 | 8785 | 45 | 3 | 48 |
Total number of gains: 180; Total number of losses: 25; Total Number of normals: 283.
Somatic mutations of MATN4:
Generating mutation plots.
Highly correlated genes for MATN4:
Showing top 20/308 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MATN4 | NFIL3 | 0.767296 | 3 | 0 | 3 |
| MATN4 | GRIN3B | 0.757712 | 3 | 0 | 3 |
| MATN4 | EXOC3L1 | 0.754998 | 3 | 0 | 3 |
| MATN4 | TSNARE1 | 0.746956 | 3 | 0 | 3 |
| MATN4 | INTS1 | 0.743572 | 3 | 0 | 3 |
| MATN4 | POLR2A | 0.736734 | 3 | 0 | 3 |
| MATN4 | LDB1 | 0.736643 | 3 | 0 | 3 |
| MATN4 | FIBCD1 | 0.730291 | 3 | 0 | 3 |
| MATN4 | SH2B1 | 0.72995 | 4 | 0 | 4 |
| MATN4 | ZNF683 | 0.729069 | 3 | 0 | 3 |
| MATN4 | ADIG | 0.727241 | 3 | 0 | 3 |
| MATN4 | BCDIN3D-AS1 | 0.722644 | 3 | 0 | 3 |
| MATN4 | CABIN1 | 0.721774 | 3 | 0 | 3 |
| MATN4 | MUC6 | 0.721421 | 3 | 0 | 3 |
| MATN4 | TMEM143 | 0.712872 | 3 | 0 | 3 |
| MATN4 | LRRC14 | 0.70854 | 3 | 0 | 3 |
| MATN4 | LRRC55 | 0.706226 | 3 | 0 | 3 |
| MATN4 | EEF1D | 0.705545 | 3 | 0 | 3 |
| MATN4 | ZNF334 | 0.703346 | 3 | 0 | 3 |
| MATN4 | SNX25 | 0.699255 | 3 | 0 | 3 |
For details and further investigation, click here
