| Full name: DnaJ heat shock protein family (Hsp40) member C17 | Alias Symbol: FLJ10634 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 55192 | HGNC ID: HGNC:25556 | Ensembl Gene: ENSG00000104129 | OMIM ID: 616844 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DNAJC17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC17 | 55192 | 219861_at | -0.2858 | 0.4079 | |
| GSE20347 | DNAJC17 | 55192 | 219861_at | -0.2564 | 0.0224 | |
| GSE23400 | DNAJC17 | 55192 | 219861_at | -0.0897 | 0.0129 | |
| GSE26886 | DNAJC17 | 55192 | 219861_at | 0.1125 | 0.6677 | |
| GSE29001 | DNAJC17 | 55192 | 219861_at | -0.3708 | 0.0462 | |
| GSE38129 | DNAJC17 | 55192 | 219861_at | -0.1981 | 0.3561 | |
| GSE45670 | DNAJC17 | 55192 | 219861_at | -0.3848 | 0.0234 | |
| GSE53622 | DNAJC17 | 55192 | 101519 | -0.2422 | 0.0000 | |
| GSE53624 | DNAJC17 | 55192 | 51246 | -0.4777 | 0.0000 | |
| GSE63941 | DNAJC17 | 55192 | 219861_at | -0.3444 | 0.4774 | |
| GSE77861 | DNAJC17 | 55192 | 219861_at | -0.1475 | 0.3216 | |
| GSE97050 | DNAJC17 | 55192 | A_23_P140698 | -0.2150 | 0.4412 | |
| SRP007169 | DNAJC17 | 55192 | RNAseq | -3.1523 | 0.0000 | |
| SRP008496 | DNAJC17 | 55192 | RNAseq | -2.9201 | 0.0000 | |
| SRP064894 | DNAJC17 | 55192 | RNAseq | -0.7405 | 0.0120 | |
| SRP133303 | DNAJC17 | 55192 | RNAseq | -0.9645 | 0.0000 | |
| SRP159526 | DNAJC17 | 55192 | RNAseq | -1.3501 | 0.0000 | |
| SRP193095 | DNAJC17 | 55192 | RNAseq | -0.6684 | 0.0000 | |
| SRP219564 | DNAJC17 | 55192 | RNAseq | -1.0859 | 0.0031 | |
| TCGA | DNAJC17 | 55192 | RNAseq | 0.0530 | 0.4583 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by DNAJC17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC17 | 55192 | 3 | 6 | 21 | |
| GSE20123 | DNAJC17 | 55192 | 3 | 6 | 21 | |
| GSE43470 | DNAJC17 | 55192 | 4 | 6 | 33 | |
| GSE46452 | DNAJC17 | 55192 | 3 | 7 | 49 | |
| GSE47630 | DNAJC17 | 55192 | 8 | 11 | 21 | |
| GSE54993 | DNAJC17 | 55192 | 4 | 6 | 60 | |
| GSE54994 | DNAJC17 | 55192 | 5 | 7 | 41 | |
| GSE60625 | DNAJC17 | 55192 | 4 | 0 | 7 | |
| GSE74703 | DNAJC17 | 55192 | 4 | 5 | 27 | |
| GSE74704 | DNAJC17 | 55192 | 2 | 4 | 14 | |
| TCGA | DNAJC17 | 55192 | 11 | 18 | 67 |
Total number of gains: 51; Total number of losses: 76; Total Number of normals: 361.
Somatic mutations of DNAJC17:
Generating mutation plots.
Highly correlated genes for DNAJC17:
Showing top 20/125 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC17 | NUDT16L1 | 0.720057 | 3 | 0 | 3 |
| DNAJC17 | TMEM37 | 0.713012 | 3 | 0 | 3 |
| DNAJC17 | SH2D1B | 0.680172 | 3 | 0 | 3 |
| DNAJC17 | CABP7 | 0.640034 | 3 | 0 | 3 |
| DNAJC17 | IL17RE | 0.608982 | 4 | 0 | 3 |
| DNAJC17 | FBXO38 | 0.605398 | 4 | 0 | 3 |
| DNAJC17 | MIEF2 | 0.603674 | 4 | 0 | 4 |
| DNAJC17 | GRIPAP1 | 0.603158 | 4 | 0 | 3 |
| DNAJC17 | SOX6 | 0.600048 | 5 | 0 | 3 |
| DNAJC17 | DRD4 | 0.598982 | 3 | 0 | 3 |
| DNAJC17 | ABAT | 0.597412 | 7 | 0 | 5 |
| DNAJC17 | MAFG | 0.595664 | 4 | 0 | 3 |
| DNAJC17 | PLD4 | 0.59077 | 5 | 0 | 4 |
| DNAJC17 | HES5 | 0.588991 | 4 | 0 | 3 |
| DNAJC17 | P2RY1 | 0.587588 | 3 | 0 | 3 |
| DNAJC17 | VEPH1 | 0.586666 | 4 | 0 | 3 |
| DNAJC17 | MAGIX | 0.586033 | 5 | 0 | 3 |
| DNAJC17 | PRSS27 | 0.583868 | 6 | 0 | 4 |
| DNAJC17 | ACER1 | 0.583697 | 5 | 0 | 4 |
| DNAJC17 | SLC35C1 | 0.57999 | 9 | 0 | 6 |
For details and further investigation, click here
