| Full name: exosome component 7 | Alias Symbol: hRrp42p|Rrp42p|RRP42|EAP1|KIAA0116|p8 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 23016 | HGNC ID: HGNC:28112 | Ensembl Gene: ENSG00000075914 | OMIM ID: 606488 |
Screen Evidence:
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Expression of EXOSC7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EXOSC7 | 23016 | 212627_s_at | -0.0949 | 0.7447 | |
| GSE20347 | EXOSC7 | 23016 | 212627_s_at | -0.0780 | 0.6157 | |
| GSE23400 | EXOSC7 | 23016 | 212627_s_at | 0.0212 | 0.7702 | |
| GSE26886 | EXOSC7 | 23016 | 212627_s_at | -0.1940 | 0.5292 | |
| GSE29001 | EXOSC7 | 23016 | 212627_s_at | -0.2648 | 0.3137 | |
| GSE38129 | EXOSC7 | 23016 | 212627_s_at | 0.0515 | 0.6858 | |
| GSE45670 | EXOSC7 | 23016 | 212627_s_at | -0.1637 | 0.1659 | |
| GSE53622 | EXOSC7 | 23016 | 44619 | -0.5674 | 0.0000 | |
| GSE53624 | EXOSC7 | 23016 | 44619 | -0.5510 | 0.0000 | |
| GSE63941 | EXOSC7 | 23016 | 212627_s_at | 0.4358 | 0.1940 | |
| GSE77861 | EXOSC7 | 23016 | 212627_s_at | -0.1885 | 0.1440 | |
| GSE97050 | EXOSC7 | 23016 | A_23_P58102 | -0.0434 | 0.9273 | |
| SRP007169 | EXOSC7 | 23016 | RNAseq | 0.6136 | 0.1651 | |
| SRP008496 | EXOSC7 | 23016 | RNAseq | 0.3161 | 0.3189 | |
| SRP064894 | EXOSC7 | 23016 | RNAseq | -0.0583 | 0.7693 | |
| SRP133303 | EXOSC7 | 23016 | RNAseq | -0.3730 | 0.0142 | |
| SRP159526 | EXOSC7 | 23016 | RNAseq | -0.0661 | 0.7757 | |
| SRP193095 | EXOSC7 | 23016 | RNAseq | -0.3198 | 0.0048 | |
| SRP219564 | EXOSC7 | 23016 | RNAseq | -0.1887 | 0.5751 | |
| TCGA | EXOSC7 | 23016 | RNAseq | -0.0359 | 0.5420 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EXOSC7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EXOSC7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EXOSC7 | 23016 | 0 | 17 | 13 | |
| GSE20123 | EXOSC7 | 23016 | 0 | 17 | 13 | |
| GSE43470 | EXOSC7 | 23016 | 0 | 21 | 22 | |
| GSE46452 | EXOSC7 | 23016 | 2 | 17 | 40 | |
| GSE47630 | EXOSC7 | 23016 | 1 | 24 | 15 | |
| GSE54993 | EXOSC7 | 23016 | 7 | 2 | 61 | |
| GSE54994 | EXOSC7 | 23016 | 0 | 35 | 18 | |
| GSE60625 | EXOSC7 | 23016 | 5 | 0 | 6 | |
| GSE74703 | EXOSC7 | 23016 | 0 | 16 | 20 | |
| GSE74704 | EXOSC7 | 23016 | 0 | 12 | 8 | |
| TCGA | EXOSC7 | 23016 | 1 | 74 | 21 |
Total number of gains: 16; Total number of losses: 235; Total Number of normals: 237.
Somatic mutations of EXOSC7:
Generating mutation plots.
Highly correlated genes for EXOSC7:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EXOSC7 | OR10G8 | 0.773878 | 3 | 0 | 3 |
| EXOSC7 | MIXL1 | 0.759672 | 3 | 0 | 3 |
| EXOSC7 | RIPK4 | 0.741197 | 3 | 0 | 3 |
| EXOSC7 | KLHL10 | 0.740957 | 4 | 0 | 4 |
| EXOSC7 | SDR42E1 | 0.710681 | 3 | 0 | 3 |
| EXOSC7 | PTK6 | 0.705482 | 5 | 0 | 4 |
| EXOSC7 | NEK10 | 0.69725 | 3 | 0 | 3 |
| EXOSC7 | TMEM37 | 0.691878 | 3 | 0 | 3 |
| EXOSC7 | GPT | 0.680464 | 3 | 0 | 3 |
| EXOSC7 | ECHDC3 | 0.679404 | 5 | 0 | 4 |
| EXOSC7 | GGT6 | 0.675642 | 4 | 0 | 3 |
| EXOSC7 | PPL | 0.673279 | 4 | 0 | 4 |
| EXOSC7 | PRSS8 | 0.671715 | 3 | 0 | 3 |
| EXOSC7 | EFNA5 | 0.670606 | 4 | 0 | 4 |
| EXOSC7 | SLC25A47 | 0.669429 | 3 | 0 | 3 |
| EXOSC7 | TEX13A | 0.668054 | 3 | 0 | 3 |
| EXOSC7 | C19orf53 | 0.667298 | 4 | 0 | 4 |
| EXOSC7 | CROT | 0.662085 | 4 | 0 | 4 |
| EXOSC7 | AZU1 | 0.660865 | 3 | 0 | 3 |
| EXOSC7 | SEMA3F | 0.657302 | 4 | 0 | 3 |
For details and further investigation, click here
